A5068275170- Streptococcal Infections and Treatments
- Bacterial biofilms and quorum sensing
- Otolaryngology and Infectious Diseases
- Oral microbiology and periodontitis research
- Zoonotic diseases and public health
- Bacteriophages and microbial interactions
- Antimicrobial Peptides and Activities
- Bacillus and Francisella bacterial research
- Genomics and Phylogenetic Studies
- Infective Endocarditis Diagnosis and Management
- Hepatitis Viruses Studies and Epidemiology
- Biochemical and Structural Characterization
- Legionella and Acanthamoeba research
- Parasites and Host Interactions
- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Breastfeeding Practices and Influences
- Microbial Community Ecology and Physiology
Mahsa University
2013-2020
University of Malaya
2012
Quorum sensing (QS) is a key regulator of virulence factors and biofilm formation in Gram-negative bacteria such as Pseudomonas aeruginosa . Microorganisms that inhabit soil are strategic importance the discovery compounds with anti-QS properties. The objective study was to test culture extract taxonomically novel species Paenibacillus strain 139SI for its inhibitory effects on QS-controlled both vitro vivo sp. used LasA protease, LasB elastase, pyoverdin production, P. well evaluate...
Diseases of the tonsils are becoming more resistant to antibiotics due persistence bacteria through formation biofilms. Therefore, understanding microbiology and pathophysiology such diseases represent an important step in management biofilm-related infections. We have isolated microorganisms, evaluated their antimicrobial susceptibility, detected presence bacterial biofilms tonsillar specimens correlation with clinical manifestations diseases. a total 140 palatine were collected from 70...
The effectiveness of many antimicrobial agents is currently decreasing; therefore, it important to search for alternative therapeutics. Our study was carried out assess the in vitro antibiofilm activity using microtiter plate assay, characterize bioactive compounds Ultra Performance Liquid Chromatography-Diode Array Detection and Chromatography-Mass Spectrometry test oral acute toxicity on Sprague Dawley rats extract derived from a novel bacterial species Paenibacillus strain 139SI. results...
The dawn of maternal vaccination is an important milestone in breastmilk immunity.Breastmilk per se has immunopotential that protects the infant from childhood diseases both immediate neonatal period and long term.Its immune nutritive attributes confer this exclusive early nourishment a cutting edge defence no other human nutrient can yet offer.Evidence maturing naiveté system its potential to differentiate commensal pathogenic microbes as well antimicrobial action are briefly reviewed.The...
Paenibacillus spp. are Gram-positive, facultatively aerobic, bacilli-shaped endospore-forming bacteria. They have been detected in a variety of environments, such as soil, water, forage, insect larvae, and even clinical samples. The strain 139SI (GenBank accession No.: JF825470.1) from three strains isolates investigated here was chosen the type proposed novel species. other two similar were 140SI (JF825471.1) 141SI (JQ734548.1). These identified members genus on basis phenotypic...
Emerging infectious diseases are infections that have recently appeared in a population over defined period of time whereas, re-emerging those were once health problem particular region or country and now emerging again. Parasitic represent serious many developing countries started spreading to developed nations via international traveling immigration. Malaysia is facing challenges caused by various parasitic pathogens. The lack awareness among disadvantaged populations such as the Orang...
Diagnosis and treatment of chronic tonsillitis (CT) recurrent (RT) are common problems seen in any otolaryngology clinic. Antibiotic therapy usually fails to prevent the recurrences these infections leaving patient with no choice but surgery (tonsillectomy). This study aims identify bacteriology both tonsillar swabs biopsies specimens among children adult patients diagnosed CT RT (infected tonsils). In addition obstructive sleep apnea (OSA) hypertrophy (TH) (non-infected tonsils) all...
Background: Hospitals waters are preferable sites for pathogenic bacteria to exist due the presence of areas that predisposes stagnation as well temperatures optimal microbial growth. Hospitalized patients can be exposed these waterborne pathogens while bathing, improper handwashing or even during contact with medical equipment rinsed such which puts them and healthcare workers at high risk acquiring healthcare-associated infections. Moreover, monitoring in facilities is generally limited by...