Streptococcus mutans is the main etiological agent for dental caries. Recently, photodynamic therapy (PDT) has been introduced as a new modality in bacterial decontamination.This vitro study was carried out to evaluate susceptibility of antibacterial PDT using two different photosensitizers and light sources.Standard suspensions S. were exposed laser at 662 nm Radachlorin or LED 630 combination with Toluidine blue O (TBO). Radiation-only groups, photosensitizer alone, groups no treatment...

This Perspective article explores the challenges associated with direct application of photobiomodulation (PBM) to gut and presents a novel hypothesis for indirect health modulation through oral microbiome alteration. Given difficulties in delivering PBM effectively deep gastrointestinal tissues, an alternative approach involves targeting microbiome, which has demonstrated relationship microbiome. Research indicates that applied cavity could selectively alter microbial composition....

This study assessed the effects of 808 nm diode laser on gene expression receptor activator nuclear factor kappa beta ligand (RANKL) and osteoprotegerin (OPG), key regulators bone remodeling, in exosomes derived from osteoblast-like cells. The cultured MG63 cells were subjected to irradiation at energy densities 3 J/cm², 6 9 along with a control group no intervention. sessions conducted twice, 24-hour interval between them. Next target isolated, mRNA levels RANKL OPG genes using qPCR. level...

This study investigated the photobiomodulation effect of an 810-nm diode laser in adjunction with topical anesthesia on pain perception during infiltration primary maxillary molars children.

Introduction: The adhesion ability of mesenchymal stem cells can significantly affect their viability and is considered a prerequisite for cell therapy. current study sought to evaluate the effect fibroblast growth factor 2 (FGF2) low-level laser therapy (LLLT), either individually or in conjunction, on proliferation periodontal ligament (PDLSCs) when applied first day seeding. Methods: experimental groups this comprised control group different combinations adjunctive FGF2 (50 ng/mL) LLLT...

Background: Photobiomodulation therapy involves exposing tissues to light sources, including light-emitting diodes or low-level lasers, which results in cellular function modulation. The molecular mechanism of this treatment is revealed, demonstrating that depending on the settings utilized, it has potential elicit both stimulatory and inhibitory reactions. Objective: current systematic review aimed evaluate impact photobiomodulation dental stem cells provide an evidence-based conclusion...

Introduction: Photobiomodulation therapy (PBM) is emerging as an effective strategy for the management of wound healing. The application red and near infra-red light sources in laser has been subject most researches recent literature. Considering lack sufficient evidence assessing blue PBM, we aimed to investigate photobiomodulation effect a diode on proliferation migration cultured human gingival fibroblast cells preliminary vitro study.Methods: Human were irradiated with at 445 nm...

Introduction: Several techniques such as using citric acid, plastic curettes, ultrasonic devices, and lasers have been suggested for debridement of contaminated implant surfaces. This comparative investigation aimed to assess compare the effects Er, Cr: YSGG laser super-saturated acid on dental Methods: In this in-vitro study, 12 failed implants were collected randomly divided into 2 groups (6 in group A, 6 B). Also, one was considered control. The horizontally sectioned coronal apical...

This study aimed to explore the efficacy of Nd:YAG laser-assisted periodontal therapy for management patients with stage II-IV periodontitis.Patients who presented residual pockets were enrolled. After non-surgical (NSPT), test sites received laser (first entrance pocket: 3 W, 100 μs, 20 Hz; second entrance: 4 600 Hz) and control placebo (laser off). Periodontal probing depth (PPD), clinical attachment level (CAL), gingival recession (GR), bleeding on (BOP), plaque index (PI) recorded at...

This study investigated the effect of photobiomodulation (PBM) with 980 nm diode laser as monotherapy and in combination compressive tensile orthodontic forces on expression osteoprotegerin (OPG), receptor activator nuclear factor-κB ligand (RANKL), sclerostin (SOST) periostin (POSTN), by human periodontal ligament cells. Isolated cells were cultured subjected to either (10% elongation) or (25 g cm-2 ) for 24 48 h. Subsequently, received PBM (100 mW power, 3 6 J energy density) immediately...

Abstract There are limited data on comparison of pulsed and continuous wave in photobiomodulation therapy (PBM). This study aimed to investigate the effect PBM with 980 nm laser proliferation migration human gingival fibroblasts (HGF) cells. Cultured HGF were divided into three main groups: (1) irradiated mode (frequencies 50 25 KHz; energy densities 3 5 J/cm 2 ), (2) (energy 3.2 5.2 (3) no irradiation as control group. rate was measured by MTT assay at 24, 48, 72 h post irradiation. In...

Abstract This study evaluated the effect of photobiomodulation therapy (PBMT) using 660 and 808 nm diode lasers (individual in combination) on periodontal ligament mesenchymal stem cells (PDLSCs) presence zoledronic acid (ZA). PDLSCs were cultured for 48 h DMEM complete medium containing 5 μM ZA. PBMT was done three times with a 24‐h interval groups 1 (660 nm, J/cm 2 ), (880 3 + nm) either normal or ZA‐treated culture medium. Control did not receive PBMT. Twenty‐four hours post‐irradiation,...

This study aimed to compare the intra and postoperative complications of frenectomy procedure with a surgical scalpel versus 445 nm 980 diode lasers.

The present study aimed to compare the effect of photobiomodulation with different energy densities on angiogenic differentiation human periodontal ligament stem cells (hPDLSCs) and from exfoliated deciduous teeth (SHED). Photobiomodulation therapy a 660 nm diode laser (2.4 J/cm

Juvenile hyaline fibromatosis (JHF) is an unknown hereditary disorder with variable penetrance. The characterizations of this disease consist different signs and symptoms such as multiple tumorous (tumor-like) muco-cutaneous proliferation, gingival hypertrophy, perianal lesions, articular contractures, osteolytic lesions. A 3-year-old girl numerous painless nodular masses on her gingival, ear anal areas presented in case report. Based characteristic histological features, the diagnosis JHF...