A5028762657- Functional Brain Connectivity Studies
- Ion channel regulation and function
- Cardiac electrophysiology and arrhythmias
- Impact of Technology on Adolescents
- Mental Health Research Topics
- Neural and Behavioral Psychology Studies
- Child Development and Digital Technology
- Gambling Behavior and Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- EEG and Brain-Computer Interfaces
- Heart Rate Variability and Autonomic Control
- Mind wandering and attention
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Chromatography in Natural Products
- Neurotransmitter Receptor Influence on Behavior
- Personality Disorders and Psychopathology
- Sleep and Wakefulness Research
- Emotional Labor in Professions
- Behavioral Health and Interventions
- Treatment of Major Depression
- Cognitive Abilities and Testing
- Bullying, Victimization, and Aggression
- Receptor Mechanisms and Signaling
- Dementia and Cognitive Impairment Research
Hannam University
2021-2024
University of Maryland, Baltimore
2019-2022
Boramae Medical Center
2012-2021
Seoul National University
2013-2021
Seoul Metropolitan Government
2021
Claremont Graduate University
2019
Duke University Hospital
2015-2016
Duke Medical Center
2015-2016
Duke University
2016
University of Virginia
2012
Previous studies have reported associations between aggression and Internet addiction disorder (IAD), which has also been linked with anxiety, depression, impulsiveness. However, the causal relationship IAD thus far not clearly demonstrated. This study was designed to (a) examine association (b) investigate mediating effects of impulsivity in cases predicts or IAD. A total 714 middle school students Seoul, South Korea, were asked provide demographic information complete Young's Addiction...
Abstract The present study compared neural connectivity and the level of phasic synchronization between populations in patients with Internet gaming disorder (IGD), alcohol use (AUD), healthy controls (HCs) using resting-state electroencephalography (EEG) coherence analyses. For this study, 92 adult males were categorized into three groups: IGD (n = 30), AUD HC 32). group exhibited increased intrahemispheric gamma (30–40 Hz) to groups regardless psychological features (e.g., depression,...
We aimed to develop a machine learning (ML) classifier detect and compare major psychiatric disorders using electroencephalography (EEG). retrospectively collected data from medical records, intelligence quotient (IQ) scores psychological assessments, quantitative EEG (QEEG) at resting-state assessments 945 subjects [850 patients with (six large-categorical nine specific disorders) 95 healthy controls (HCs)]. A combination of QEEG parameters including power spectrum density (PSD) functional...
KCNMA1 forms the pore of BK K + channels, which regulate neuronal and muscle excitability. Recently, genetic screening identified heterozygous variants in a subset patients with debilitating paroxysmal non-kinesigenic dyskinesia, presenting or without epilepsy (PNKD3). However, relevance mutations basis for clinical heterogeneity PNKD3 has not been established. Here, we evaluate relative severity three patient neurons, mice. In heterologous cells, N999S D434G channels displayed...
Previous studies have reported promising results regarding the effect of repeated virtual cue exposure therapy on nicotine dependence. This study aimed to compare effectiveness (CET) and cognitive behavioral (CBT) for Thirty subjects with dependence participated in 4 weeks treatment either CET (n=15) or CBT (n=15). All patients were male, none received replacement during period. The main setting used this was a bar. primary foci offered (a) smoking cessation education, (b) withdrawal...
Maintaining employment is difficult for patients with schizophrenia because of deterioration psychosocial and cognitive functions. Such usually require vocational rehabilitation training, which both demanding costly. In this study, we developed a virtual reality-based training program (VR-VRTP) such evaluated its feasibility as an alternative to traditional programs. We the VR-VRTP include various situations commonly encountered in two types occupations: convenience store employee...
The sacred lotus (Nelumbo nucifera) contains many phytochemicals and has a history of human use. To determine which compounds may be responsible for reported psychotropic effects, we used in silico predictions the identified phytochemicals. Nuciferine, an alkaloid component Nelumbo nucifera Nymphaea caerulea, had predicted molecular profile similar to antipsychotic compounds. Our study characterizes nuciferine using vitro vivo pharmacological assays.Nuciferine was first characterized...
Background and aims Impulsivity is a core feature of gambling disorder (GD) related to the treatment response. Thus, it interest determine objective neurobiological markers associated with impulsivity in GD. We explored resting-state electroencephalographic (EEG) activity patients GD according degree impulsivity. Methods In total, 109 subjects were divided into three groups Barratt impulsiveness scale-11 (BIS-11) scores: high (HI; 25th percentile BIS-11 scores, n = 29), middle (MI; 26th-74th...
We divided hospital workers into two groups according to whether one was an interpersonal service worker (ISW) or not (non-ISW). then explored differences between these in job stress and emotional labor type investigated the mediating factors influencing their relationships.Our participants included both ISW (n = 353) non-ISW 71) workers. administered Korean Standard Occupational Stress Scale Short Form measure Emotional Labor indicate characteristics. also Beck Depression Inventory-II of...
Abstract Heart rate variability (HRV) can be used to represent the regulatory adaptive system and is a proxy for neurovisceral integration. Consistent with view that, like other addictions, Internet gaming disorder (IGD) involves disrupted function, present study hypothesized that IGD patients would show (a) decreased HRV, (b) ineffective functional neural connectivity, (c) differential patterns of association between HRV connectivity relative healthy controls (HCs). The included 111 young...
The hyperarousal model demonstrates that instability of sleep-wake regulation leads to insomnia symptoms and various neurophysiological states. Previous studies have shown states appear in chronic patients are not limited sleep at nighttime but stable characteristics extend into the daytime. However, this phenomenon is mainly measured bedtime, so it hard determine whether maintained throughout a 24 h cycle or if just appears bedtime.We examined resting state qEEG (quantitative...
Functional impairment in daily activity is a cornerstone distinguishing the clinical progression of dementia. Multiple indicators based on neuroimaging and neuropsychological instruments are used to assess levels disease severity; however, it remains unclear how multivariate patterns predictors uniquely predict functional ability relative importance various differs.In this study, 881 older adults with subjective cognitive complaints, mild (MCI), dementia Alzheimer's type completed brain...
KCNMA1 encodes the pore-forming α subunit of ‘Big K + ’ (BK) large conductance calcium and voltage-activated channel. BK channels are widely distributed across tissues, including both excitable non-excitable cells. Expression levels highest in brain muscle, where critical regulators neuronal excitability muscle contractility. A global deletion mouse ( –/– ) is viable but exhibits pathophysiology many organ systems. Yet despite important roles animal models, consequences dysfunctional humans...
Temperament is close to susceptibility stress and the increased level of may lead problematic smartphone use (PSU). In this study, relationships between harm avoidance (HA) as a personality trait, daily traits, PSU in children adolescents were investigated.At baseline, all participants (184 adolescents, mean age 13.15 years) completed questionnaires on using Smartphone Addiction Scale-Short Version (SAS-SV) Korean Proneness Scale (SAPS). The Daily Hassles Questionnaire (DHQ) Junior Character...
The diagnosis of a paroxysmal dyskinesia is difficult and status dystonicus rare life threatening movement disorder characterised by severe, frequent or continuous episodes dystonic spasms. A 25 year old woman with chronic ataxia presented facial twitching, writhing arms, oculogyric crisis visual auditory hallucinations. She developed respiratory failure was ventilated. No cause found so whole exome sequencing performed this revealed novel, non-synonymous heterozygous variant in exon 11 the...