A5019296113- Ultrasound and Cavitation Phenomena
- Rocket and propulsion systems research
- Spacecraft and Cryogenic Technologies
- Fluid Dynamics and Heat Transfer
- Kidney Stones and Urolithiasis Treatments
- Particle Dynamics in Fluid Flows
- Cyclone Separators and Fluid Dynamics
- Fluid Dynamics Simulations and Interactions
- Cavitation Phenomena in Pumps
- Electrohydrodynamics and Fluid Dynamics
- Laser-induced spectroscopy and plasma
- Computational Fluid Dynamics and Aerodynamics
- Gas Dynamics and Kinetic Theory
- Nuclear Physics and Applications
- Photoacoustic and Ultrasonic Imaging
- Pediatric Urology and Nephrology Studies
- Laser Design and Applications
- COVID-19 impact on air quality
- Membrane Separation Technologies
- Nuclear Engineering Thermal-Hydraulics
- Fluid Dynamics and Mixing
- Combustion and Detonation Processes
- Algal biology and biofuel production
- Lipid Membrane Structure and Behavior
- Anesthesia and Neurotoxicity Research
Indian Institute of Technology Kharagpur
2015-2024
Colorado School of Mines
2024
Duke University
2023-2024
Indian Institute of Information Technology Allahabad
2023
Czech Academy of Sciences, Institute of Microbiology
2021
Recent studies indicate that cavitation may play a vital role in laser lithotripsy. However, the underlying bubble dynamics and associated damage mechanisms are largely unknown. In this study, we use ultra-high-speed shadowgraph imaging, hydrophone measurements, three-dimensional passive mapping (3D-PCM), phantom test to investigate transient of vapor bubbles induced by holmium:yttrium aluminum garnet their correlation with solid damage. We vary standoff distance (SD) between fiber tip...
Objectives To explore the optimal laser settings and treatment strategies for thulium fibre (TFL) lithotripsy, namely, those with highest efficiency, lowest thermal injury risk, shortest procedure time. Materials Methods An in vitro kidney model was used to assess efficacy of TFL lithotripsy upper calyx. Stone ablation experiments were performed on BegoStone phantoms at different combinations pulse energy (E P ) frequency (F) determine settings. Temperature changes risks monitored using...
Bubbles oscillating in the presence of ultrasound is commonly employed biomedical applications for drug delivery, enhanced thrombolysis, and transport manipulation cells. This possible because bubbles tend to interact with undergo periodic shape changes known as shape-mode oscillation, concomitant generation liquid agitation or streaming. phenomenon examined both experimentally theoretically on a single bubble at frequency (45 ± 1) kHz. Effects ultrasonic power flowfield were explored....
This paper is associated with a video winner of 2021 American Physical Society's Division Fluid Dynamics (DFD) Milton van Dyke Award for work presented at the DFD Gallery Motion. The original available online Motion, https://doi.org/10.1103/APS.DFD.2021.GFM.V0038.
In this study, we conduct direct numerical simulations to investigate the dynamics of interacting cavitation bubbles near a curved surface in liquid nitrogen, which serves as surrounding fluid medium. Our are carried out under both atmospheric and over-pressurized conditions, spanning pressures from 40 200 kPa above pressure. We analyze effects over-pressure on bubble morphologies, oscillation periods, velocity micro-jets. Additionally, briefly explore shearing action high-speed micro-jets...
You have accessJournal of UrologyStone Disease: Basic Research & Pathophysiology (MP63)1 May 2024MP63-03 INVESTIGATING OPTIMAL SETTINGS AND THERMAL INJURY RISK OF THE THULIUM FIBER LASER IN AN ANATOMICAL KIDNEY MODEL Ezra J. Margolin, Arpit Mishra, Robert A. Medairos, David L. Barquin, Junqin Chen, Francois Soto-Palou, Jodi Antonelli, Glenn M. Preminger, Charles D. Scales, Gary Faerber, Pei Zhong, and Michael E. Lipkin MargolinEzra Margolin , MishraArpit Mishra MedairosRobert Medairos...
For low cost, high thrust, space missions with specific impulse and reliability, inert weight needs to be minimized thereby increasing the delivered payload. Turbopump feed system for a liquid propellant rocket engine (LPRE) has highest power ratio. Turbopumps are primarily equipped an axial flow inducer achieve angular velocity suction pressure in combination increased reliability. Performance of turbopump strongly depends on performance inducer. Thus, designing LPRE turbopump, demands...
A subphase exchange cell was designed to observe fluid–fluid interfaces with a conventional optical microscope while simultaneously changing the chemistry. Materials including phospholipids, asphaltenes, and nanoparticles at exhibit unique morphological changes as function of bulk-phase These can affect their interfacial material properties and, ultimately, emergent bulk films, foams, emulsions produced from such systems. In this work, we combine experiments, computational fluid dynamics...
You have accessJournal of UrologyStone Disease: Surgical Therapy (Including ESWL) V (MP78)1 May 2024MP78-04 EVALUATION OF CHAR FORMATION USING THE THULIUM FIBER LASER: STANDOFF BETWEEN HIGH VERSUS LOW PULSE ENERGY David L. Barquin, Junqin Chen, Arpit Mishra, Robert A. Medairos, Ezra J. Margolin, Jodi Antonelli, Glenn M. Preminger, Charles D. Scales, Gary Faerber, Pei Zhong, and Michael E. Lipkin BarquinDavid Barquin , ChenJunqin Chen MishraArpit Mishra MedairosRobert Medairos MargolinEzra...
Kidney stone disease is a major public health issue. By breaking stones with repeated laser irradiation, lithotripsy (LL) has become the main treatment for kidney disease. Laser-induced cavitation closely associated damage in LL. Monitoring activities during LL thus crucial to optimizing and maximizing efficiency. In this study, we have developed three-dimensional super-resolution passive mapping (3D-SRPCM), which bubble positions can be localized an accuracy of 40 μm, 1/10th acoustic...
Jets produced by the interaction of collapsing cavitating bubbles containing high-pressure gases can be utilized for wide variety applications e.g. particle erosion, medical purposes (lithotripsy, sonoporation), tannery effluent treatment, etc. Among many parameters, this jetting is largely influenced spatial orientation bubbles, their times inception, relative bubble size ratio. In context, multiple are able to generate numerous simultaneous jets, under suitable conditions, hence operating...
As a part of the developmental effort towards realization staged combustion cycle based liquid rocket engine, program on simulation LOX booster pump for performance characterization has been taken up. Earlier reported work shows that inducer works satisfactorily under cavitating conditions throttling range varying from 90% to 113%. However stall occurs below designed flow rate which is be strongly associated with inlet backflow vortices due separation [1]. It envisaged leading edge sweep may...
The high impact erosive pressure resulting from collapsing cavitating bubble has advantages in stone fragmentation and shock wave lithotripsy. They carry damage potential also can erode the curved hydrofoil of any turbo-machinery, and, still somewhat obscure cryogenic liquids. Once material loses its surface smoothness, flow-field surrounding bubbles is affected by newly formed irregular geometry. In this way, collapse significantly influenced curvature rigid boundary. work, a near dipped...
To obtain high specific work output with small mass flow rate, high-pressure ratios across the turbines are required in liquid rocket engine turbopumps. An impulse-type supersonic turbine can achieve this. prevent losses due to low blade aspect ratio and issues related manufacturing industrial problems, partial admission configuration is adopted. Partial entry a achieved by adjusting extent of nozzle arc admission, leading strong unsteady circumferential asymmetry parameters rotor passage,...
Background: An institutional quarantine facility in India reported 5 cases 9 days. The latter 2 incited a suspicion of internal outbreak as they were residing different room than the index and onset symptoms was after expiry period. Subsequently, 75 more tested positive from this facility.Methods: A retrospective-prospective study conducted. Data regarding travel history, health-events thereafter, daily activities, layout standard procedures followed collected. epidemiological pattern...