- Analytical Chemistry and Chromatography
- Botanical Research and Chemistry
- Heat Transfer and Optimization
- Analytical Methods in Pharmaceuticals
- Antibiotics Pharmacokinetics and Efficacy
- Analytical Chemistry and Sensors
- Anesthesia and Sedative Agents
- Heat Transfer and Boiling Studies
- Water-Energy-Food Nexus Studies
- Chemical synthesis and alkaloids
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Cloud Computing and Resource Management
- Electrochemical sensors and biosensors
- Cholinesterase and Neurodegenerative Diseases
- Anaerobic Digestion and Biogas Production
- Green IT and Sustainability
- Advanced biosensing and bioanalysis techniques
- Municipal Solid Waste Management
- Pharmacogenetics and Drug Metabolism
- Plant biochemistry and biosynthesis
- Thermochemical Biomass Conversion Processes
- Respiratory Support and Mechanisms
- Alkaloids: synthesis and pharmacology
- Chemical Synthesis and Analysis
University College London
2020-2024
University of Glasgow
2021-2024
Wellcome / EPSRC Centre for Interventional and Surgical Sciences
2022-2024
McMaster University
1979-2023
University College Hospital
2022
Jadavpur University
2018-2021
University College London Hospitals NHS Foundation Trust
2020
CRUK Lung Cancer Centre of Excellence
2020
University of Ottawa
2016
Children's Hospital of Eastern Ontario
2016
Biochar production via pyrolysis of various organic waste has potential to reduce dependence on conventional energy sources and mitigate global warming potential. Existing models for predicting biochar yield compositions are computationally-demanding, complex, have low accuracy extrapolative scenarios. Here, two data-driven machine learning based Multi-Layer Perceptron Neural Network Artificial Neuro-Fuzzy Inference System developed. The predict a variety input feedstock process conditions....
Biodiesel has the potential to mitigate fossil fuel-related carbon emission and energy insecurity challenges. There are limited studies examining impacts of biodiesel production scales on environmental impacts, while such information will be valuable for guiding practical system design. This work applied approach life cycle assessment evaluate from rapeseed oil which accounts 80% European biofuel market. It was shown that centralized large-scale localized small-scale schemes have annual...
Anaerobic digestion (AD)-based biogas production mitigates the environmental footprint of organic wastes (e.g., food waste and sewage sludge) facilitates a circular economy. The work proposed an integrated system where thermal energy demand AD is supplied using air source heat pump (ASHP). compared to baseline system, by natural gas-based heating system. Several machine learning models are developed for predicting production, among which Gaussian Process Regression (GPR) showed superior...
It is shown by tracer experiments with DL-[2-3H,5-14C]- and DL-[(RS)-5-3H,5-14C]rnithine, that the metabolic conversion of ornithine into proline, in three plant species (Nicotiana tabacum, Datura stramonium, Lupinus angustifolius), takes place maintenance delta-hydrogen atoms but loss alpha-hydrogen atom. This indicates a route via alpha-keto-delta-aminovaleric acid (5-amino-2-oxopentanoic acid) disproves accepted glutamic gamma-semialdehyde (2-amino-5-oxopentanoic acid).
Quantifying the global warming potential of existing water infrastructure is an important step in realising industry's commitment to net-zero carbon. Whilst there has been improved understanding centralized urban infrastructure, rigorous analyses smaller-scale rural systems are rare. This work adopts a life cycle assessment ascertain drinking treatment works and wastewater associated with five Scottish islands: Arran, Iona, Jura, Barra, Vatersay. The systems, from source sink, along use...
The biogenetic hypothesis that the Lycopodium alkaloids are modified dimers of pelletierine (2, 3) was tested experimentally in Lycopodiumtristachyum, Pelletierine is indeed incorporated into lycopodine, but only one unit entered alkaloid, rather than two units, as predicted. thus requires modification.Δ 1 -Piperideine serves a specific precursor lycopodine. Two Δ -piperideine moieties such way identity C-2 and -6 each units maintained.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGeneral method for the determination of precursor configuration in biosynthetic precursor-product relations. Derivation pipecolic acid from D-lysine, and piperidine alkaloids L-lysineE. Leistner, R. N. Gupta, Ian D. SpenserCite this: J. Am. Chem. Soc. 1973, 95, 12, 4040–4047Publication Date (Print):June 1, 1973Publication History Published online1 May 2002Published inissue 1 June...
The biosynthesis of sedamine (IX) was studied in excised shoots Sedum acre L. Phenyl-alanine serves as the precursor C 6 – 2 side chain. piperidine nucleus is derived from lysine, which incorporated by way a nonsymmetrical intermediate. These findings are consistent with Robinson's classical biogenetic hypothesis. They incompatible polyacyl origin skeleton.