A5074723692- Genetics and Physical Performance
- Sports Performance and Training
- Cardiovascular Effects of Exercise
- Muscle metabolism and nutrition
- Exercise and Physiological Responses
- Muscle Physiology and Disorders
- Infant Nutrition and Health
- Digestive system and related health
- Winter Sports Injuries and Performance
- Growth Hormone and Insulin-like Growth Factors
- Nutrition, Genetics, and Disease
- Breastfeeding Practices and Influences
- Retinoids in leukemia and cellular processes
- Physical Activity and Health
- Adipose Tissue and Metabolism
- Food Security and Health in Diverse Populations
- Dental Health and Care Utilization
- Pediatric health and respiratory diseases
- Antioxidant Activity and Oxidative Stress
- Bone health and osteoporosis research
- Skin Protection and Aging
- Body Composition Measurement Techniques
- Oral microbiology and periodontitis research
- Neuropeptides and Animal Physiology
- Intracerebral and Subarachnoid Hemorrhage Research
Marmara University
2019-2025
To evaluate the effects of rs1799750 1G/2G polymorphism MMP1 gene and rs1800470 T/C TGF-ß1 on temporomandibular disk displacement vertical facial development. Sixty-six individuals were examined radiographically prior to evaluation signs/symptoms disorders according Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Class II, hyperdivergent with TMD (+) assigned Group 1, (-) included in 2; while I, normodivergent 3. For genetic analysis, oral mucosa swab samples...
In this study, we aimed to compare ACTN3 rs1815739, PPARA rs4253778 and IL-6 rs1800795 polymorphisms with aerobic endurance in volleyball players. Twenty-two players (age: 21.59 ± 2.70 years; height: 1.87 7.92 m; body weight: 80.99 8.14 kg; fat: 12.05 5.78%) participated the study voluntarily. DNA extraction from buccal epithelial cells was provided by a commercial kit. Real-Time PCR performed for genotyping. Statistical analysis of test results using SPSS 23 (SPSS Inc., Chicago, IL, USA)...
Background: The aim of our study is to determine the genotype distribution ADRA2A rs1800544 gene polymorphism in fencing athletes and compare results with sedentary control group. In addition, we intend these Depression Anxiety Stress Scale (DASS) Sports Injury (SIAS) applied Methods: Buccal epithelial cells were collected from 14 volunteer 22 individuals who participated DNA was isolated. analyzed using Real-Time PCR. Data SPSS 25.0 software. Results: study, examined 43% CG genotype, 57% CC...
α-Actinin-3 is one of the key components Z-line structure sarcomeres and also have importance in muscle cell signaling processes. Therefore, gene rs1815739 polymorphism most analysed potential genetic biomarkers sports studies. We aimed to evaluate genotypic allelic distribution Turkish athletes. For this purpose, a total 131 athletes (39 cyclists, 34 sprinters distance athletes, 33 volleyball players, 15 bodybuilders 10 ironmen) 89 sedentary individuals were enrolled study. Genomic DNA from...
Acacetin is a natural flavone compound, which found in several plants as Robinia pseudoacacia and demonstrated to have anticancerogenic activities many types of cancer (e.g., human nonsmall cell lung cancer, prostate). Colorectal carcinoma (CRC) one the serious health problems complex disease. We intended find more effective new candidate for treatment colon hence, we designed this study investigate effects acacetin on CRC (HT-29, HCT 116) vitro.The was carried out with methods that...
Skin aging is affected by internal and external factors. The stratum corneum consists of keratinocytes, as these mature in the epidermis, their proliferative potential gradually decreases skin undergoes programmed destruction. There are many single nucleotid polymorphism (SNP)s associated with aging. COL1A1, MMP1, CYP1A2 genes responsible for collagen degradation production. Changes affect MCR1 STXBP5L important ultraviolet (UV) protection moisturizing skin. Due to changes genes, cannot be...
Objective: Athletic performance is affected by genetic and environmental factors. Bodybuilding has been increasing around the world in recent years it accepted that factors affecting athletic are most important influences to achieve success bodybuilding. The aim of our study determine distribution COL1A1 rs1800012 polymorphism associated with ligament tendon injuries due muscle tears weight training compare results sedentary individuals. Material Methods: A total 15 Turkish bodybuilders 50...
The aim of this study is twofold: (1) to identify differences in certain anaerobic parameters (10m sprint, 30m power, and Illinois agility tests) between professional amateur soccer players, (2) determine whether there a difference the ACTN3 gene polymorphism players. Ultimately, goal reveal which contribute differentiation these two aspects. A total 133 volunteer including 71 professionals 62 amateurs, participated research. DNA extraction from buccal epithelial cells was performed using...
Objectives: Trigeminal neuralgia (TN) is a disease that occurs in the distribution region of trigeminal nerve and frequently recurrent pain. Serotonin (5-HT) acts on neurotransmitters central nervous system. The study aims to examine relationship between sensitivity pain intensity serotonin receptor gene (5-HTR2A) rs6311 polymorphism patients by examining TN genetically. Materials Methods: consisted 10 healthy individuals. Genotyping 5-HTR2A using DNA isolated from blood, Real-Time PCR...
Purpose: The purpose of this research is to investigate the occurrence ACE I/D and ACTN3 rs1815739 variations in sub-elite fitness athletes determine which gene distinctive by comparing genotype allele frequencies with sedentary individuals. Material Methods: 41 volunteers participated study. Genetic analyzes were determined using molecular-based methods such as DNA isolation a commercial kit, Real-time polymerase chain reaction (Real-Time PCR), Polymerase (PCR) after blood collection EDTA...
Abstract Objective Caries formation is a process affected by various factors. Studies have shown that genetic factors also play role in caries formation. The aim of our study to examine the effects matrix metalloproteinase (MMP)3 (rs679620) and vitamin D receptor (VDR) (rs731236) gene polymorphisms on Materials Methods Following routine oral examinations individuals aged between 20 44 years, diagnosis was made according decayed, missing, filled teeth (DMFT) index, experimental group defined...
Research has been conducted to explore the genetic basis of trigeminal neuralgia, a persistent pain condition that impacts nerve. COMT is an enzyme responsible for inactivating substances and hormones containing catechol catecholamines. Previous research linked gene polymorphism with various conditions, including migraine. Our aimed investigate correlation between neuralgia rs4680 gene. We project which included 10 individuals diagnosed 30 healthy as controls. Following collection blood...
This study investigated the minichromosome maintenance 6 (MCM6) rs4988235 polymorphism in professional football players, comparing genotype and allele frequencies with a sedentary control group. The group comprised 64 participants no history of athletic activity, while athlete included 20 players. DNA extraction from blood samples was performed using PureLink isolation kit, following manufacturer's instructions. Real-Time PCR employed to analyze MCM6 isolated DNA. Statistical analysis...
The aim of this study was to examine whether ACTN3 rs1815739 polymorphism, which causes the deficiency alpha-actinin-3 muscle protein, is related formation open bite malocclusion.
Sample ÖZÇalışmamızda, profesyonel futbolcularda alfa aktinin-3 geni rs1815739 polimorfizmini belirlemeyi, genotip ve allel frekanslarını sedanter bireyler ile karşılaştırmayı hedefledik.Ayrıca futbolcuların genotipleri mevkileri arasındaki ilişkiyi saptamayı
The purpose of this study was to reveal the differences between ACTN3 genotype (RR, RX, XX) and aerobic performance [Yo-Yo IRT1 (m), VO2 max (ml/kg/min)] in professional regional amateur league soccer players which these parameters a distinctive factor athletes.71 (age: 23.66 ± 4.11 years; body height: 1.79 6.99 m; weight: 76.02 6.76 kg; fat: 11.59±3.11 %) 62 23.63 ±3.77 1.81 5.77 76.36 7.53 15.60±4.65 volunteered for study. After DNA extraction from buccal epithelial cells via...