A5063665976- RNA regulation and disease
- CRISPR and Genetic Engineering
- Fuel Cells and Related Materials
- RNA Research and Splicing
- Ocean Acidification Effects and Responses
- RNA and protein synthesis mechanisms
- Marine Bivalve and Aquaculture Studies
- Physiological and biochemical adaptations
Kent State University
2021-2024
Parkinson's Disease (PD) is the second most common neurodegenerative disease behind Alzheimer's Disease, currently affecting more than 10 million people worldwide and 1.5 times males females. The progression of PD results in loss function due to neurodegeneration neuroinflammation. etiology multifactorial, including both genetic environmental origins. Here we explored changes RNA editing, specifically editing through actions Adenosine Deaminases Acting on (ADARs), PD. Analysis ADAR skeletal...
Abstract Parkinson’s Disease (PD) is a multifactorial disease with heterogenous phenotypes that vary across individuals, as well by age and sex. Therefore, it likely multiple interacting factors, such environmental influences aging, genetic including dynamic RNA (ADAR, Adenosine Deaminases Acting on RNA) editing, may play role in PD pathology. In this analysis of 317 transcriptomes healthy controls, prodromal patients aged 65 years or older, from Project Markers Initiative dataset, we...
Abstract Parkinson’s Disease (PD) is the second most common neurodegenerative disease behind Alzheimer’s Disease, currently affecting more than 10 million people worldwide and 1.5 times males females. The progression of PD results in loss function due to neurodegeneration neuroinflammation. etiology multifactorial, including both genetic environmental origins. Here we explored changes RNA editing, specifically editing through actions Adenosine Deaminases Acting on (ADARs), PD. Analysis ADAR...