A5048740262- Protein Structure and Dynamics
- Computational Drug Discovery Methods
- Bioinformatics and Genomic Networks
- vaccines and immunoinformatics approaches
- Machine Learning in Bioinformatics
- RNA and protein synthesis mechanisms
- Enzyme Structure and Function
- Monoclonal and Polyclonal Antibodies Research
Koç University
2021-2024
Proteins are vital components of the biological world and serve a multitude functions. They interact with other molecules through their interfaces participate in crucial cellular processes. Disruption these interactions can have negative effects on organisms, highlighting importance studying protein–protein for developing targeted therapies diseases. Therefore, development reliable method investigating is paramount importance. In this work, we present an approach validating using learned...
Abstract Summary We present a web-based server for navigating and visualizing possible interactions between SARS-CoV-2 human host proteins. The are obtained from HMI_Pred which relies on the rationale that virus proteins mimic structural alignment of viral protein with one side protein–protein interface determines mimicry. mimicked predicted interactions, binding sites presented. user can choose 18 structures visualize potential 3D complexes it forms is also provided. superimpose two...
Abstract Proteins are vital components of the biological world, serving a multitude functions. They interact with other molecules through their interfaces and participate in crucial cellular processes. Disruptions to these interactions can have negative effects on organism, highlighting importance studying protein-protein for developing targeted therapies diseases. Therefore, development reliable method investigating is paramount importance. In this research, we present an approach...