Jianzhong Guan

ORCID: 0000-0001-5304-8663
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About
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Research Areas
  • Pelvic and Acetabular Injuries
  • Pregnancy-related medical research
  • Hernia repair and management
  • Hip and Femur Fractures
  • MicroRNA in disease regulation
  • Medical Imaging and Analysis
  • Spinal Fractures and Fixation Techniques
  • Hip disorders and treatments
  • Orthopaedic implants and arthroplasty
  • Bone fractures and treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Extracellular vesicles in disease
  • Surgical Sutures and Adhesives
  • RNA modifications and cancer
  • Pluripotent Stem Cells Research
  • Single-cell and spatial transcriptomics
  • Hemostasis and retained surgical items
  • Mesenchymal stem cell research
  • Wound Healing and Treatments
  • Trauma and Emergency Care Studies
  • Total Knee Arthroplasty Outcomes
  • Circular RNAs in diseases
  • Neurogenesis and neuroplasticity mechanisms

First Affiliated Hospital of Bengbu Medical College
2020-2024

Bengbu Medical College
2022-2023

Diabetic osteoporosis (DO) presents significant clinical challenges. This study aimed to investigate the potential of magnetic nanoparticle-enhanced extracellular vesicles (GMNP

10.1007/s10565-024-09877-2 article EN cc-by Cell Biology and Toxicology 2024-07-05

Objective: To compare the functional and radiological outcome of combine compression interlocking intramedullary nail (InterTan) proximal femoral anti-rotation II (PFNA-II) in treatment elderly patients with intertrochanteric fractures.
 Methods: As a retrospective cohort study, records 88 fractures treated our hospital from January 1st, 2019 to July 31st, 2021 were retrospectively reviewed. According records, it included 45 InterTan (Group-A) 43 PFNA-II (Group-B). The operation safety...

10.12669/pjms.39.1.6946 article EN cc-by Pakistan Journal of Medical Sciences 2022-12-01

The percutaneous iliosacral screw is a common procedure for treating pelvic posterior ring instability. Traditional X-ray fluoroscopy placement has the advantages of decreased bleeding and trauma, but it also some drawbacks, such as increased radiation exposure dislocation. purpose this study was to establish safe, effective, quick approach putting screws treatment unstable damage utilizing simulated based on preoperative computed tomography (CT) planning.From February 2019 June 2020, we...

10.1186/s12891-022-05155-6 article EN cc-by BMC Musculoskeletal Disorders 2022-03-08

Osteoporosis is a common bone metabolic disease with increased fragility and fracture rate. Effective diagnosis treatment of osteoporosis still need to be explored due the increasing incidence disease.Single-cell RNA-seq was acquired from GSE147287 dataset. Osteoporosis-related genes were obtained chEMBL. Cell subpopulations identified characterized by scRNA-seq, t-SNE, clusterProfiler, other computational methods. "limma" R packages used identify all differentially expressed genes. A model...

10.1155/2022/6830635 article EN cc-by Mediators of Inflammation 2022-09-25

BackgroundWound gnawing and/or scratching in rats often occurs experimental models, causing suture breakage and wound dehiscence, consequently affecting results wasting resources. This study aimed to investigate the impact of combined postoperative use Allgower-Donati (A-D) pattern sweet foods on breakage, inflammation, healing wounds.Materials methodsSprague Dawley (SD) (n = 48) were treated for linear wounds back by four procedures: simple suture, with foods, A-D foods. Additionally, CD68...

10.1016/j.heliyon.2023.e13934 article EN cc-by-nc-nd Heliyon 2023-02-25

Abstract Objective The INFIX technique is becoming one of the most commonly performed surgical procedures for anterior pelvic ring instability injuries. purpose this article to compare clinical outcomes modified subcutaneous internal fixation (M-INFIX) with conventional (C-INFIX) Patients and methods A retrospective analysis 36 cases unstable injuries treated operatively at our institution, 20 which were C-INFIX 16 M-INFIX. Data collected included age, gender, ISS score, fracture typing,...

10.1186/s12893-023-02205-1 article EN cc-by BMC Surgery 2023-11-16

To investigate the early effectiveness of Ti-Robot assisted femoral neck system (FNS) in treatment elderly Garden type Ⅱ and Ⅲ fractures.A retrospective analysis was conducted on clinical data 41 patients with fractures who were admitted between December 2019 August 2022 met selection criteria. Among them, 21 cases treated FNS internal fixation (study group), 20 solely (control group). There no significant difference baseline data, including gender, age, side, cause injury, time from injury...

10.7507/1002-1892.202308051 article EN PubMed 2023-12-15

<title>Abstract</title> Background When the traditional sacroiliac screw is used in treatment of Day type II crescent fracture dislocation pelvis, entry point may be located near line and lead to failure pressurization, at same time, short channel iliac segment has defects such as insufficient holding power. This study proposes a modified technique investigates value crescentic dislocations pelvis. METHODS We retrospectively analyzed 44 patients with pelvic who underwent surgical from...

10.21203/rs.3.rs-4817453/v1 preprint EN cc-by Research Square (Research Square) 2024-09-02

To investigate the effectiveness of modified internal fixator (INFIX) to fix anterior pelvic ring for Tile C1.3 fracture by comparing with traditional INFIX.The patients fractures admitted between April 2018 and June 2021 were taken as study objects. Of them, 55 cases included in according selection criteria. During operation, was fixed INFIX 30 (modified group) 25 (control group). The posterior sacroiliac screws. There no significant difference two groups gender, age, cause injury, time...

10.7507/1002-1892.202208014 article EN PubMed 2022-12-15

Abstract Purpose: This research introduced a novel approach that combines Three-dimensional(3D) printed guide-plate with preoperative virtual iliosacral screws to guide the insertion of intraoperative screws, and compares its effectiveness safety traditional surgical procedures. Methods: 59 patients in our hospital were randomized group (n=30) or (n=29) after receiving percutaneous iliosacrals for unstable posterior pelvic ring injuries. Gender, age, injury mechanism, sacrum type, fracture...

10.21203/rs.3.rs-2531826/v1 preprint EN cc-by Research Square (Research Square) 2023-02-02

Abstract Objective The INFIX technique is becoming one of the most commonly performed surgical procedures for anterior pelvic ring instability injuries. purpose this article to compare clinical outcomes modified subcutaneous internal fixation (M-INFIX) with conventional (C-INFIX) Patients and Methods: A retrospective analysis 36 cases unstable injuries treated operatively at our institution, 20 which were 16 INFIX. Data collected included age, gender, ISS score, fracture typing, operative...

10.21203/rs.3.rs-2817986/v1 preprint EN cc-by Research Square (Research Square) 2023-04-24

Abstract Objective: To explore the clinical efficacy of pararectus approach combined with 3D printing technique for surgical treatment partial acetabular fractures. Methods : We retrospectively evaluated 33 (20 males and 13 females) patients fractures in period June 2017 to December 2018; According judet-letenneal classification: 11 cases were anterior column fracture, 10 double 7 posterior half transverse,3 transverse 2 case was "T" fracture. For all cases, is used print model. Pre-bent...

10.21203/rs.2.23813/v2 preprint EN cc-by Research Square (Research Square) 2020-03-05

Abstract Background: It is technically challenging to restore hip rotation center exactly in total arthroplasty (THA) for patients with end-stage osteoarthritis secondary developmental dysplasia of the (DDH) due complicated acetabular morphology changes.In this study, we developed a new method and rapidly THA assistance three dimensional (3-D) printing technology. Methods: Seventeen (21 hips) DDH who underwent were included study. Simulated operations performed on 3-D printed models...

10.21203/rs.3.rs-26630/v1 preprint EN cc-by Research Square (Research Square) 2020-05-18
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