Rheumatoid arthritis is an inflammatory, autoimmune disease where oxidative stress has been proposed to contribute the joint tissue damage. To establish whether measurement of redox status in blood mirrors oxidant at sites inflammation patients with rheumatoid arthritis, we concomitantly examined their by spectrophotometry and/or flow cytometry. The basal levels total reactive oxygen species (ROS), superoxide and hydroxyl radicals were significantly raised neutrophils sourced from peripheral...

The evolving landscape of personalized medicine necessitates a shift from traditional therapeutic interventions towards precision-driven approaches. Embracing this paradigm, our research probes the efficacy aqueous crude extract (ACE) Calocybe indica in cervical cancer treatment, merging botanical insights with advanced molecular research. We observed that ACE exerts significant influences on nuclear morphology and cell cycle modulation, further inducing early apoptosis showcasing prebiotic...

Background. The association between subclinical thyroid dysfunction (defined by no symptoms or clinical features of hypothyroidism but biochemically TSH level in the range above 5 miu/ml below 10 with normal FT4 level) and Acute Coronary Syndrome (ACS) is not known so far. This study was done to calculate prevalence patients ACS. Methods. A retrospective chart review 1100 consecutive who presented Emergency Department suggestive ACS admitted. They were later classified 3 categories that...

<p class="abstract"><strong><span lang="EN-US">Background: </span></strong>The association between thyroid dysfunction and DM has long been recognized, although the prevalence of among diabetes population varies in different studies. This study destined to know recently diagnosed type 2 mellitus patients. </p><p lang="EN-US">Methods: </span></strong>Retrospective chart review 60 patients with mellituswas done. Total (male 51, female9)...

Retinal nerve fibre layer (RNFL) is a sensitive structure, which affected by anaemia due to hypoxia. A timely detection of RNFL thinning may aid preventing devastating complications. Optical coherence tomography (OCT) measures with accuracy and helps in detecting the retinal anaemic patients. This study was destined evaluate patients their correlation haemoglobin level.It prospective comparative study. Total 151 were included this Patients diseases excluded from After initial evaluation,...

Synergistic effect of mushroom extracts with standard antibiotics against pathogenic bacteria is beneficial for treating infectious diseases. The present investigation tested the antibacterial activity and synergistic from an edible mushroom, Calocybe indica, antibiotics. minimum inhibitory concentration (MIC) different C. indica was checked opportunistic such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, S. epidermidis, Bacillus subtilis using...

<p class="abstract"><strong><span lang="EN-US">Background: </span></strong>Hepatocellular carcinoma is the one of commonest tumour worldwide. A detailed clinical profile including its etiology and vast presentation not available in Eastern India.</p><p lang="EN-US">Methods: </span></strong>Retrospective chart review 90 patients with HCCwas done. Total (male 81, female9) fulfillingdiagnostic criteria for HCC adopted by Barcelona-2000 EASL...

<p><strong>Background:</strong> To identify prevalence of the novel risk factors among young patients with Acute Coronary Syndrome (ACS) and having no or minimal conventional factors. <strong></strong></p><p><strong>Methods</strong>: Total 70 ( male 48 , female 22 ) who were admitted in our hospital ACS, without any traditional analyzed for hsCRP [highly sensitive C reactive protein ], Lp(a) [Lipoprotein(a)], Homocysteine uric acid...

Background: Dengue fever (DF) has become a major global public health problem. In India, epidemics are becoming more frequent. infection ranges from mild illness to severe form of haemorrhagic and shock syndrome which may prove fatal. Early recognition meticulous management very important save precious lives this killer disease.Methods: Total 82 patients (63 male, 19 female) admitted with diagnosis dengue were analysed in details clinical features outcomes.Results: Fever was the most...

Sebaceous cysts are common in day to practice. But unusual locations with atypical presentations may pose problem diagnosis as well management. Here we have reported 4 cases of such atypicality which very uncommon and unusual.

Neurocysticercosis (NCC) is one of the commonest causes central nervous system related helminthic infection. Cysticercosis endemic in most developing world and infection with HIV (Human Immunodeficiency Virus) becoming more frequent those areas. There a risk development exacerbations previously latent patient following initiation HAART (Highly Active Anti-Retroviral Therapy), termed as Immune Reconstitution Inflammatory Syndrome (IRIS). Very few case NCC manifestation IRIS has been reported....

Hypothyroidism can present with the variety of clinical features; however, bleeding manifestations as a sole presentation hypothyroidism is extremely rare. Hemostatic disorder may be manifestation several underlying etiology. Here, we report case 14 year old girl who initially presented diathesis without any other symptoms suggestive thyroid dysfunction but later on investigations was found to suffering from severe hypothyroidism. Keywords: Activated partial thromboplastin time, Bleeding...

Background: Prevalence of cerebrovascular diseases (CVD) is rising in India along with its morbid impact. Till now there no study from Eastern to reflect the current scenario this part world. This destined know and analyse several epidemiologic factors behind India. Methods: 108 patients who were admitted symptoms stroke analysed based on parameters. They investigated, treated their outcomes followed. Results: Correlation between clinical findings radiological confirmation was much more case...

Ruptured Sinus of Valsalva (RSOV) is very rare in paediatric age group, 3rd decade being the usual presentation age. Patient may present with asymptomatic murmur to cardiogenic shock and fatal outcomes. High degree suspicion expertise required confirm or rule out diagnosis. Here we have reported a case RSOV 6-year-old boy who presented features hyperdynamic circulation.

26-year-old lady admitted with shortness of breath and chest discomfort for last one half months. She had no history pain. was not suffering from any major illness neither she taking medications on regular basis.