A5023910483- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Psoriasis: Treatment and Pathogenesis
- Inflammatory Myopathies and Dermatomyositis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Infectious Diseases and Tuberculosis
- Liver Disease Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Atherosclerosis and Cardiovascular Diseases
- Musculoskeletal synovial abnormalities and treatments
- Hepatitis C virus research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Renal Diseases and Glomerulopathies
- Bone and Joint Diseases
- Liver Diseases and Immunity
- Musculoskeletal Disorders and Rehabilitation
- Inflammasome and immune disorders
- T-cell and B-cell Immunology
- Acute Ischemic Stroke Management
- Monoclonal and Polyclonal Antibodies Research
- Osteoarthritis Treatment and Mechanisms
Institute of Post Graduate Medical Education and Research
2016-2025
R. G. Kar Medical College and Hospital
1979-2024
Medical College and Hospital, Kolkata
2004-2023
Bose (United States)
2012-2023
Bose Institute
2020
Mentor
2018
Technical Data Analysis (United States)
2018
Center for Rheumatology
2015
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2013
Post Graduate Institute of Medical Education and Research
2009
Objectives. There are no valid instruments to measure disease activity in Takayasu arteritis (TA). We aim provide a assess clinical with or without incorporating acute phase reactants. Methods. The Indian Clinical Activity Score (ITAS) was initially derived from manifestations scored the Disease Extent Index (DEI.Tak). ITAS validated by group of physicians scoring both live and paper cases for inter-rater reliability (IRR), convergence BVAS, correlation Physician’s Global Assessment (PGA)...
SSc is characterized by fibrotic changes in the skin and lung, mainstay of treatment has been CYC. B cell involvement suggests that rituximab (RTX) may also be therapeutic benefit. The aim study was to compare efficacy safety RTX compared with CYC retarding progression interstitial lung disease manifestations primary SSc.We randomly assigned 60 patients dcSSc, age 18-60 years involvement, monthly pulses 500 mg/m2 or 1000 mg × 2 doses at 0, 15 days. Primary outcomes were forced vital capacity...
Background: Very little evidence exists concerning the possible impairment of children's intellectual function in relation to arsenic exposure utero and during childhood. Methods: We conducted a cross-sectional study among 351 children age 5 15 years who were selected from source population 7683 people West Bengal, India, 2001–2003. Intellectual was assessed with 6 subtests Wechsler Intelligence Scale for Children as well Total Sentence Recall test, Colored Progressive Matrices pegboard...
Rheumatoid arthritis is an inflammatory, autoimmune disease where oxidative stress has been proposed to contribute the joint tissue damage. To establish whether measurement of redox status in blood mirrors oxidant at sites inflammation patients with rheumatoid arthritis, we concomitantly examined their by spectrophotometry and/or flow cytometry. The basal levels total reactive oxygen species (ROS), superoxide and hydroxyl radicals were significantly raised neutrophils sourced from peripheral...
<b>Background</b> : Systemic lupus erythematosus (SLE) is an autoimmune disease with multiorgan involvement. The skin the second most commonly affected organ. SLE lesions can produce considerable morbidity resulting from painful lesions, alopecia, disfigurement, etc. Skin in patients may be specific (LE specific) or non specific). Acute cutaneous LE (Lupus has a strong association systemic and non-specific always indicate activity for which present to rheumatologists internists.<i> </i>...
Free radicals are involved in the pathogenesis of Rheumatoid arthritis, a systemic autoimmune disorder characterized by unchecked synovial inflammation. Allylpyrocatechol, phytoconstituent Piper betle leaves, has potent anti-inflammatory activity and this study evaluated its anti-oxidant effect on infiltrate patients with arthritis. The ex vivo allylpyrocatechol upon generation reactive oxygen species neutrophils, macrophages lymphocytes was measured flow cytometry using...
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disorder wherein the contributory role of oxidative stress has been established in synovial fluid. As availability fluid limited, this study aimed to evaluate peripheral blood patients with RA, relationship if any, between extent terms generation reactive oxygen species (ROS) neutrophils, plasma NADPH oxidase and myeloperoxidase activity markers damage, circulating cytokines disease score (DAS28). In neutrophils demonstrated an...
The objectives of this study were to develop a scoring system with colour Doppler ultrasound (CDUS) in patients Takayasu's arteritis, correlate the CDUS score Indian Activity Score (ITAS) and assess degree agreement between angiogram diagnosis arteritis.Nineteen angiographically confirmed arteritis fulfilling three or more 1990 ACR criteria evaluated. Their ITASs recorded. A system, CDUS-Kolkata (CDUS-K), was devised based on presence stenosis altered flow patterns. It then correlated ITAS....
Cardiac tamponade is a rare but life-threatening complication of systemic lupus erythematosus (SLE).To describe incidence, risk factors and treatment cardiac in large cohort Indian patients with SLE.This retrospective study was conducted at the Department Rheumatology, IPGMER, Kolkata, India from May 2014 to December 2016 on admitted SLE. Lupus-related serositis diagnosed after excluding other causes, such as infection, malignancy or heart failure.Of 409 SLE, pericarditis 25.4% (104/409)...
Several countries have participated in WHO COPCORD. The Global Disease Burden program (GBD) reports selected MSK disorders. We used a COPCORD India protocol to estimate the national burden of Trained paramedics standard questionnaires screen population and identify respondents with current and/or past pain (non-traumatic) 12 survey sites (8 rural); cross-sectional design prospective data. measures were recorded; was self-reported (on human manikin). site rheumatologist examined each...
A descriptive study was conducted to find out physical, social problems & emotional stress of the mothers babies who are admitted in NICU/SNCU selected government hospital. The objectives were mothers, identify relationship between physical problems, association with socio- demographic variables. conceptual framework adopted for this Holistic care model. Non-experimental research approach survey design study. One ninety-five (195) R. G. Kar Medical College Hospital as sample through...
Background and purpose Stroke‐associated early seizures ( ES ) often complicate the initial course of acute stroke. This study intended to estimate rate predictive factors for impact on clinical outcome in patients with first‐ever Materials methods Consecutive stroke admitted D epartment M edicine from J une 2010 ecember 2011 were prospectively included. defined as occurring within 7 days Patients history epilepsy, transient ischaemic attack, subarachnoid haemorrhage cerebral venous...
The authors made a field-survey of mental morbidity in all the tribal and caste groups residing cluster villages West Bengal, India, found that, each group, higher socio-economic classes had rates morbidity. Different having similar cultural pattern showed no significant difference their Groups different patterns differed significantly In some neurotic disorders were absent.
Aim This study aimed to assess the sensitivity and specificity of ultrasonographic features gout in intercritical chronic stages compared between patients with persistent high serum uric acid (SUA) low SUA. Methods Adult confirmed by demonstration monosodium urate crystals were recruited, if they or stage clinically. Ultrasonographic examination first metatarsophalangeal joints (MTPJs) knee both sides done a blinded rheumatologist trained musculoskeletal ultrasound. Results Sixty-two 30...
A psychiatric field‐survey was conducted in three villages West Bengal, India order to correlate the prevalence of mental morbidity with socio‐economic status families. The sample divided into four groups on basis religion or caste. Total had no statistically significant relationship any groups. In total it directly related. Higher classes significantly higher rates. Psychoses were not correlated Neuroses showed a rate upper strata two groups; other trend same direction. differences their...
Objective: To detect evolution of ultrasonographic signs deposition monosodium urate crystals (MSUC) in gouty joints by serial ultrasonography after initiation urate-lowering therapy (ULT). Methods: Adult gout patients were examined ULT with target serum uric acid (SUA) < 6 mg/dL. Results: Thirty-eight male mean age 50 ± 11 years, median disease duration 48 months and baseline SUA level 8.8 1.5 mg/dL recruited. Ultrasonographic evidence MSUC was detected 89.74% first metatarsophalangeal...