The objective of this article is to highlight the clinical features, screening, diagnosis, treatment, and prevention gastric cancer (GC). Early GC often asymptomatic leading frequent delays in diagnosis. Weight loss persistent abdominal pain are most common symptoms at initial diagnosis typically involves a combination endoscopy, biopsy, imaging studies. Endoscopic resection techniques emerging as successful treatment options for early GC. Treatment advanced include surgery chemotherapy....

Oxyntic gland adenomas (OGAs) are benign gastric neoplasms composed of gland-forming epithelial cells with predominantly chief cell differentiation resembling oxyntic glands confined to the mucosa. If tumor has submucosal invasion, it should be classified as adenocarcinoma fundic type. The OGAs can pose a diagnostic challenge, they resemble aggressive neoplasms. There no current guidelines on management OGA. Due relatively small size and low malignant potential, these lesions typically...

This review article aims to provide a comprehensive overview of recent epidemiology, pathogenesis, risk factors, and premalignant conditions gastric cancer. Worldwide, cancer is one the most common fatal cancers. The incidence mortality remain high in regions such as East Asia Eastern Europe. Although there lower United States, it remains deadly disease. Age, gender, race are non-modifiable demographic factors for developing There have been several dietary lifestyle salt preserved foods,...

Gastrointestinal bleeding from angiodysplasias in patients with aortic stenosis is termed as 'Heyde's syndrome'. We report a case of Heyde's syndrome successfully treated trans-catheter valve replacement.

We are reporting a case of massively enlarged left inguinal hernia containing the stomach and presenting with coffee ground emesis. Esophagogastroduodenoscopy (EGD) identified non-ischemic three small gastric ulcers. The patient opted for non-surgical management.

Gastric cancer is one of the most common and deadly cancers worldwide, especially amongst older males. Current data suggest gastric fifth neoplasm third cancer, with an estimated 783,000 deaths in 2018. Risk factors associated development include obesity, gastroesophageal reflux disease, Helicobacter pylori infection, low socioeconomic status. Diagnosis can be accomplished by endoscopy, which allows clinician to obtain a biopsy specimen. Endoscopic ultrasound also important modality that...

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the treatment of type 2 diabetes mellitus. We are reporting second case liraglutide-induced liver injury, with complete resolution injury after discontinuation drug.

Gastrointestinal amyloidosis is a rare condition commonly found in the setting of systemic AL amyloidosis. Amyloid can deposit throughout gastrointestinal tract and resulting symptoms vary depending on site deposition. (GI) manifestations range from weight loss or abdominal pain, to more serious complications like bleeding, malabsorption, dysmotility, obstruction. This case describes patient with known history IgG lambda amyloidosis, presenting epigastric pain unintentional have...

Mesenteric panniculitis (MP) is an inflammatory condition affecting the mesenteric adipose tissue, characterized by idiopathic and fibrotic changes. We present a case of 66-year-old woman initially diagnosed with MP, followed diagnosis follicular lymphoma six months later. Despite several proposed hypotheses, etiology MP remains poorly understood, potential associations including abdominopelvic surgery, infections, autoimmune conditions various malignancies lymphoma. Several studies have not...

INTRODUCTION: Amiodarone is a commonly used anti-arrhythmic agent and it important that physicians are familiar with the toxicity profile. We reporting case of intravenous (IV) amiodarone induced hyper-acute liver injury. CASE DESCRIPTION/METHODS: 62-year-old man history atrial fibrillation, non-ischemic cardiomyopathy tobacco abuse, was admitted fibrillation rapid ventricular response related to medication non-adherence. Patient given IV (total 1050 mg) over 24-hour period, following which...

Case Information: A 51 year old Hispanic woman was readmitted for the fifth time, within a period of six months, with vomiting, abdominal pain and diarrhea. She diagnosed Clostridium difficle colitis, when she presented similar complaints, first time. During subsequent admissions, bacteremic multiple organisms such as Klebsiella pneumoniae, Eubacterium lentum Enterococcus faecalis. index admission, patient on vancomycin taper recurrent colitis. On examination, had diffuse right...

<h3>Aim</h3> Single nucleotide polymorphisms (SNPs) near the IL28B gene region have been strongly associated with likelihood of SVR in genotype 1 HCV patients treated peginterferon/ribavirin (PR). During evaluation an exploratory diagnostic test that characterises genetic gene, impact rs1297860 on telaprevir (T)-based regimens ADVANCE trial was evaluated. <h3>Method</h3> testing performed according to a US FDA guidance governing use de-identified leftover samples for vitro testing. The...

We report a case of 60-year-old asymptomatic male with history consumption uncooked snake meat while living in the Congo basin and prior imaging showing multiple abdominal calcifications. Patient had subepithelial colonic lesions identified during screening colonoscopy microscopic examination demonstrated calcified nodule submucosa overlying normal mucosa. However, no parasite was within nodule. Given typical radiographic feature calcifications, it is very likely that patient's abnormalities...

Duodenal penetration is a late complication associated with the placement of inferior vena cava (IVC) filters. In this case report, we are presenting asymptomatic duodenal by IVC filter that was managed conservatively.

Introduction: Peptic ulcer disease (PUD) remains a significant healthcare burden despite widespread use of proton pump inhibitors. In the United States, bleeding is most common complication PUD, followed by perforation. We are reporting case hepatic and intra-abdominal abscesses secondary to subclinical gastric Case Description/Methods: A 28-year-old woman was diagnosed with severe anemia unknown etiology during workup fatigue. She suffered from arthralgias using ibuprofen 800 mg 3 times day...

Introduction: Sinonasal squamous cell carcinoma is a rare malignancy arising from the nasal cavity or paranasal sinuses. The incidence has been slowly declining and accounts for only 3% of head neck cancers. Although it typically spreads locally, metastasis to lungs, liver, bone have reported. Metastasis colon exceedingly rare, with limited number cases reported in literature. In this case report, we describe patient who presented severe iron deficiency anemia secondary cecal sinonasal...

Introduction: Pelvic varices are typically associated with evidence of portal hypertension. Portal hypertension is commonly caused by liver cirrhosis, but it can also arise due to a myriad non-cirrhotic causes. Isolated pelvic in the absence exceedingly rare and represents diagnostic challenge as mimic other conditions, including congestion syndrome, or masses. Case Description/Methods: A 34-year-old man without past medical history presented for evaluation nausea, intermittent, vague...

Introduction: Esophageal parakeratosis is a rare, asymptomatic benign finding that characterized by the presence of incomplete keratinized squamous epithelium in esophagus. This case 61-year-old man who underwent esophagogastroduodenoscopy (EGD) for evaluation chronic abdominal pain and was incidentally diagnosed with esophageal parakeratosis. Case Description/Methods: A anxiety disorder prostate hypertrophy presented upper associated nausea several months. He denied dysphagia, odynophagia,...

Introduction: Ischemic colitis (IC) is a disorder that occurs when the blood supply of large intestine becomes compromised. Known risk factors for development ischemic include congestive heart failure, atrial fibrillation, and chronic obstructive pulmonary disease, among others. The effect neurologic conditions on has seldom been studied. Parkinson’s disease (PD) in particular, which known to affect central dopinergic pathways, may play role clinical outcomes patients with colitis. Methods:...