A5004490561- Acute Kidney Injury Research
- Lipid metabolism and disorders
- Renal and related cancers
- Drug Transport and Resistance Mechanisms
- Liver Disease Diagnosis and Treatment
- Neonatal Health and Biochemistry
- Chronic Kidney Disease and Diabetes
- Chemotherapy-induced organ toxicity mitigation
- 14-3-3 protein interactions
- Organ Transplantation Techniques and Outcomes
- Erythrocyte Function and Pathophysiology
- Analytical Chemistry and Chromatography
- Renal Diseases and Glomerulopathies
- Machine Learning and Algorithms
- Pharmacological Effects of Natural Compounds
- Copper-based nanomaterials and applications
- Protein Interaction Studies and Fluorescence Analysis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced Glycation End Products research
- Muscle and Compartmental Disorders
- Alcohol Consumption and Health Effects
- Methemoglobinemia and Tumor Lysis Syndrome
- Circular RNAs in diseases
- Traditional Chinese Medicine Analysis
Anhui Medical University
2008-2024
First Affiliated Hospital of Anhui Medical University
2024
Ministry of Education of the People's Republic of China
2018-2019
Shaanxi Normal University
2009
Huaibei Normal University
2007
Acute kidney injury (AKI) is a common, complex, and severe clinical syndrome characterized by rapid decline in renal function, combined with tissue damage. Currently, the prevention treatment of AKI are focused on symptomatic treatment, rather than treating underlying causes. Therefore, there no specific to prevent except for dialysis. In this study, we used cisplatin-induced mouse human kidney-2 (HK-2) cell models evaluate protective effect eleutheroside B, an active compound traditional...
Fibroblast-like synoviocytes (FLS) obtained from the joint synovium of rheumatoid arthritis (RA) patients exhibit hyperplasia and aggressive inflammatory phenotypes. This study was designed to explore anti-inflammatory mechanism IL-6R inhibitor, tocilizumab, in FLS-mediated inflammation RA perspective non-coding RNAs (ncRNAs). To this end, we sorted primary FLS with cultured them vitro. The cells were then treated tocilizumab subjected lncRNA- miRNA-seq identify ncRNAs regulated by treatment...
Although renal fibrosis is a common complication of chronic kidney disease (CKD), effective options for its treatment are currently limited. In this study, we evaluated the protective effect and possible mechanism eleutheroside B. order to solve allergic reactions, side effects, low oral bioavailability B, successfully prepared PLGA (poly [lactic-co-glycolic acid])-eleutheroside B nanoparticles (NPs) with diameter about 128 nm. vitro in vivo results showed that could inhibit expression...