A5030351795- Nutrition and Health in Aging
- Neuroinflammation and Neurodegeneration Mechanisms
- Nutritional Studies and Diet
- Cancer-related molecular mechanisms research
- Folate and B Vitamins Research
- RNA regulation and disease
Sun Yat-sen Memorial Hospital
2022-2023
Sun Yat-sen University
2022-2023
The aggregation of α-synuclein (α-syn) promotes neuroinflammation and neuronal apoptosis, which eventually contribute to the pathogenesis Parkinson's disease (PD). Our microarray analysis experimental data indicated a significant expression difference long noncoding RNA IL6ST-AS its anti-sense strand, IL6ST, in α-synuclein-induced microglia, compared with unstimulated microglia. IL6ST is key component IL6R/IL6ST complex microglial membrane, recognizes extracellular inflammatory factors, such...
Background: Malnutrition’s prognostic impact in patients with severe stroke requiring ICU admission is not well known. This study aimed to assess the nutritional status of using geriatric risk index (GNRI) and examine association GNRI mortality that population. Methods: We identified 1145 from Medical Information Mart for Intensive Care (MIMIC-III) database divided them into low (≤98) or high (>98) groups. used a propensity score matching (PSM) method reduce confounding. Cox proportional...
As the Chinese government increasingly prioritizes high-quality and sustainable economic development, Environmental, Social, Corporate Governance (ESG) performance Total Factor Productivity (TFP) have become central topics in academic research. This study focuses on non-state-owned enterprises China, analyzing impact of ESG TFP exploring mediating role financing constraints this relationship. The findings indicate that alleviating can enhance TFP, while strong helps to ease these...