A5028303352- Infant Nutrition and Health
- Food Chemistry and Fat Analysis
- Viral gastroenteritis research and epidemiology
- Gut microbiota and health
- Biochemical Analysis and Sensing Techniques
- Phytochemicals and Antioxidant Activities
- Monoclonal and Polyclonal Antibodies Research
- Exercise and Physiological Responses
- Fatty Acid Research and Health
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Probiotics and Fermented Foods
- Morinda citrifolia extract uses
- Microbial Metabolites in Food Biotechnology
- Rheumatoid Arthritis Research and Therapies
- Antioxidant Activity and Oxidative Stress
- Digestive system and related health
- Birth, Development, and Health
- T-cell and B-cell Immunology
- Neonatal Respiratory Health Research
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Higher Education Teaching and Evaluation
- Natural product bioactivities and synthesis
- Adipose Tissue and Metabolism
Universitat de Barcelona
2016-2025
Institute of Agrifood Research and Technology
2016-2025
Centro de Investigación Biomédica en Red
2021-2025
Instituto de Salud Carlos III
2021-2025
Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition
2024
Institut National des Sciences Appliquées de Lyon
2020
Université Claude Bernard Lyon 1
2020
Centre National de la Recherche Scientifique
2020
New York University Press
2009-2017
Cambridge University Press
2009-2017
Hesperidin, found in citrus fruits, has shown a wide range of biological properties. Nonetheless, more in-depth investigation is required on the effects immune system, and particular, gut-associated lymphoid tissue, together with its relationship gut microbiota. Therefore, we aimed to establish influence oral hesperidin administration intestinal tissue microbiota composition healthy animals. Lewis rats were orally administrated 100 or 200 mg/kg three times per week for four weeks. Microbiota...
Rotavirus (RV) is considered to be the most common cause of gastroenteritis among infants aged less than 5 years old. Human milk bioactive compounds have ability modulate diarrheic process caused by several intestinal pathogens. This study aimed evaluate potential protective role a specific human oligosaccharide, 2'-fucosyllactose (2'-FL), mixture prebiotic short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides 9:1 (GOS/FOS) their combination (2'-FL+GOS/FOS) on...
Several microbial modulatory concepts, such as certain probiotics and prebiotics, confer protection against gastrointestinal infections, among which is acute diarrhea caused by the rotavirus (RV). Other microbiota modulators, postbiotics, produced during fermentation, might also have potential to counteract RV infection. In light of this, a fermented milk, made using Bifidobacterium breve C50 (BbC50) Streptococcus thermophilus 065 (St065) with prebiotic mixture—short chain...
Intensive exercise can lead to oxidative stress, which be particularly deleterious for lymphoid tissues. Hesperidin has demonstrated its antioxidant activity, but few studies focus on influence intensive training. The aim of this study was assess the impact hesperidin oxidant/antioxidant status tissues after an training program. Wistar rats were trained five weeks (five days per week), including two exhaustion tests plus three trainings week. During period, animals orally administrated with...
In the present study, we report effects of a cocoa extract on secretion and RNA expression various proinflammatory mediators by macrophages. Monocyte chemoattractant protein 1 tumor necrosis factor α (TNFα) were significantly dose-dependently diminished extract, this effect was higher than that produced equivalent concentrations epicatechin but lower isoquercitrin. Interestingly, added prior to cell activation resulted in greater inhibition TNFα secretion. Both decreased TNFα, interleukin...
Abstract Introduction The objective of this study was to evaluate the efficacy intravenous (i.v.) injection liposomally encapsulated dexamethasone phosphate (DxM-P) in comparison free DxM-P rats with established adjuvant arthritis (AA). This focused on polyethylene glycol (PEG)-free liposomes, minimize known allergic reactions caused by neutral PEG-modified (PEG-ylated) liposomes. Methods Efficacy assessed clinically and histologically using standard scores. Non-specific specific immune...
Cocoa is a rich source of flavonoids, mainly (−)-epicatechin, (+)-catechin, and procyanidins. This article reports the effect continuous cocoa intake on antioxidant capacity in plasma tissues, including lymphoid organs liver, from young rats. Weaned Wistar rats received natural (4% or 10% food intake) for three weeks, corresponding to their infancy. Flavonoid absorption was confirmed through quantification epicatechin metabolites urine. Total (TAC) activity enzymes, superoxide dismutase...
Olive oil (OO) phenolic compounds (PC) are able to influence gut microbial populations and metabolic output. Our aim was investigate whether these changes affect the mucosal immune system. In a randomized, controlled, double blind cross-over human trial, for three weeks, preceded by two-week washout periods, 10 hypercholesterolemic participants ingested 25 mL/day of raw virgin OO differing in their PC concentration origin: (1) an containing 80 mg PC/kg (VOO); (2) PC-enriched 500 from (FVOO);...
Human milk oligosaccharides are unconjugated complex glycans present in high concentration human that serve as pre-biotics and immunomodulators. They not primarily absorbed or metabolized by the infant reach lower part of intestinal tract unaltered. One main found is 2'-fucosyllactose (2'-FL). This study aimed to investigate effects daily oral administration 2'-FL healthy suckling rats. From days 2 16 life, rats were given oligosaccharide (2'-FL) vehicle (REF), weighed their stool...
Probiotic supplementation with different lactobacilli and bifidobacterial strains has demonstrated beneficial effects in infectious diarrhea caused by rotavirus (RV) young children. Preclinical models of RV infection might be a good strategy to screen for the efficacy new probiotic or test their comparative efficacy. Neonatal Lewis rats were supplemented Bifidobacterium breve M-16V, Lactobacillus acidophilus NCFM, helveticus R0052, salivarius PS2 from days 2–14 life. On day five, animals...
Background/Objectives: Diet composition is important for health, especially during critical periods such as pre-gestation (P), gestation (G), or lactation (S), due to its potential impact not only on the mother but offspring. The Mediterranean diet includes many healthy foods rich in fiber and/or polyphenols, whole grains, fruits, vegetables, beans, and nuts. present preclinical study assesses of a polyphenols (HFP diet) one those three (P, G, S, weeks each) rat gene expression small...