A5011473165- Immune Cell Function and Interaction
- Lung Cancer Research Studies
- RNA modifications and cancer
- Graphene and Nanomaterials Applications
- Electrohydrodynamics and Fluid Dynamics
- Nanoparticles: synthesis and applications
Josep Carreras Leukaemia Research Institute
2023
Universidad Europea
2022
Elucidating the adaptive mechanisms that prevent host immune response in cancer will help predict efficacy of anti-programmed death-1 (PD1)/L1 therapies. Here, we study cell-intrinsic lung (LC) to interferon-γ (IFNγ), a cytokine promotes immunoresponse and modulates programmed death-ligand 1 (PD-L1) levels. We report complete refractoriness IFNγ subset LCs as result JAK2 or IFNGR1 inactivation. A submaximal affects another shows constitutive low levels IFNγ-stimulated genes (IγSGs) coupled...
Carbon nanomaterials have received increased attention in the last few years due to their potential applications several areas. In medicine, for example, these could be used as contrast agents, drug transporters, and tissue regenerators or gene therapy. This makes it necessary know behavior of carbon biological media assure good fluidity absence deleterious effects on human health. this work, rheological characterization different graphene fetal bovine serum other fluids, such albumin water,...