About
Contact & Profiles
A5034343642
Research Areas
- Immune Cell Function and Interaction
- Pancreatic function and diabetes
- Diabetes and associated disorders
Although most patients with type 1 diabetes (T1D) retain some functional insulin-producing islet β cells at the time of diagnosis, rate further cell loss varies across individuals. It is not clear what drives this differential progression rate. CD8+ T have been implicated in autoimmune destruction cells. Here, we addressed whether phenotype and function autoreactive influence disease progression. We identified islet-specific using high-content, single-cell mass cytometry combination...
10.1172/jci126595
article
EN
Journal of Clinical Investigation
2019-12-08
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