Aizhen Zhu

ORCID: 0000-0001-5440-6370
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Reproductive Health and Technologies
  • Hematopoietic Stem Cell Transplantation
  • Hematological disorders and diagnostics
  • Mesenchymal stem cell research
  • Peroxisome Proliferator-Activated Receptors
  • Bone and Joint Diseases
  • Medicinal Plants and Bioactive Compounds
  • PARP inhibition in cancer therapy
  • Reproductive System and Pregnancy
  • Erythropoietin and Anemia Treatment
  • Lipid metabolism and disorders
  • COVID-19 Impact on Reproduction
  • Effects of Radiation Exposure
  • Cancer, Hypoxia, and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Chemotherapy-induced cardiotoxicity and mitigation

Yuncheng University
2022-2025

Shanxi Medical University
2022-2025

Yuncheng Central Hospital
2022-2023

Jinan University
2017

Jinan University
2012-2015

Objective To assess whether trigger-day progesterone (P) levels in conventional vitro fertilization (c-IVF)/intracytoplasmic sperm injection (ICSI) cycles are associated with blastocyst culture outcomes. Methods In this retrospective analysis, 747 eligible patients (747 cycles) who adopted the gonadotropin-releasing hormone (GnRH) antagonist protocol and underwent c-IVF/ICSI between January 2021 to June 2024 were recruited. The P cutoff values 1.0 1.5 ng/ml when serum was measured, 4177 day3...

10.3389/fendo.2025.1496803 article EN cc-by Frontiers in Endocrinology 2025-02-12

Objective To investigate the effect of body mass index (BMI) on progesterone (P) level trigger day in gonadotropin-releasing hormone antagonist (GnRH-ant) cycles.

10.1080/09513590.2024.2364892 article EN cc-by-nc Gynecological Endocrinology 2024-06-30

We examined whether erythropoietin (EPO) can inhibit adipogenic differentiation of mesenchymal stem cells (MSCs) in the mouse bone marrow and its underlying mechanism.We separated extracted MSCs induced using 3-isobutyl-1-methylxanthine, insulin, dexamethasone.Different concentrations EPO were added to observed by Oil Red O staining on 20th day quantitatively analyze degree cell differentiation.mRNA expression levels peroxysome proliferator-activated receptor g (PPARg), CCAAT enhancer...

10.4238/2015.june.26.5 article EN Genetics and Molecular Research 2015-01-01

Aims: To investigate the association between number of oocytes and polyspermy rate following in vitro fertilization (IVF) treatment. Materials methods: 376 IVF cycles with gonadotropin-releasing hormone (GnRH) antagonist protocol reproductive center our hospital were retrospectively included analysis, which divided into five groups according to retrieved. Group A (78 cases):1–5 oocytes, group B (118 cases): 6–10 C (94 11–15 D (55 16–20 E (31 ≥21 oocytes. According rate, then two groups....

10.1080/09513590.2023.2217270 article EN cc-by-nc Gynecological Endocrinology 2023-05-29

<title>Abstract</title> Purpose This study aimed to assess the impact of coronavirus disease 2019 (COVID-19) inactivated vaccination doses on male fertility. Methods A retrospective cohort was conducted, including 595 assisted insemination with husband's sperm (AIH) cycles involving 438 couples. Participants were categorized into three groups: unvaccinated group, 1 or 2 and 3 group based their status before insemination. Reproductive outcomes such as biochemical pregnancy, clinical ongoing...

10.21203/rs.3.rs-4284728/v1 preprint EN cc-by Research Square (Research Square) 2024-04-29

To explore the protective effects of 1,25-dihydroxy vitamin D3 (1,25-(OH)2D3) on bone marrow microenvironment in mice after irradiation and underlying molecular mechanisms, a total 150 7-wk-old male BALB/c were randomly divided into normal group, an (IR) group irradiation+1,25-(OH)2D3 (IR+VD3) group. The IR+VD3 treated with 6.0 Gy 60Coγ rays, 1,25-(OH)2D3 (dissolved DMSO, 2.5 μg/kg) was administered once per day from 2 d before to 8 irradiation. Mice IR same dose γ rays equal volume DMSO....

10.3177/jnsv.63.161 article EN Journal of Nutritional Science and Vitaminology 2017-01-01

Objective To investigate the potential and underlying molecular mechanism of salidroside in ameliorating radiation-induced bone marrow adipogenesis stimulating hematopoiesis.Methods The female BALB/c mice aged 6-7 weeks were randomly divided into normal control group,radiation group group.The radiation irradiated with 6.0 Gy 60Co γ-rays.The was intraperitoneally injected 30 mg· kg-1 · d-1 at 12 h then every day until 8th d after radiation.The treated equal volume saline as salidroside.At 14...

10.3760/cma.j.issn.0254-5098.2014.10.004 article EN Zhonghua fangshe yixue yu fanghu zazhi 2014-10-25

Objective To investigate the protective effect of 1,25-(OH) 2D3 on radiation-induced bone marrow microenvironment injury and to explore related molecular mechanism.Methods Sixty 7-week old male BALB/c mice were randomly divided into control group without any treatment; radiation exposed 6.0 Gy 60Co γ-rays with DMSO,and 1,25-(OH)2 D3 + treated 1,25-(OH)2D32.5 μg/kg dissolved in DMSO each day 6 γ-rays.The body weight peripheral white blood cells,femur histology,and proportion adipocyte area...

10.3760/cma.j.issn.0254-5098.2013.04.001 article EN Zhonghua fangshe yixue yu fanghu zazhi 2013-08-25

The aim of this study was to investigate the correlation between CDK1 protein and mRNA during oocyte maturation in vivo mouse. GV, GVBD, MI MII oocytes were obtained from mice, respectively. Western blot validated that expression increased continuously significantly with (P<0.05). Real-time qRT-PCR showed down-regulated transformation GV stages (P<0.05), up-regulated level peaked at stages. Spearman analysis indicated poor (R=0.200). This finding suggested increase not entirely caused by...

10.1387/ijdb.220002za article EN The International Journal of Developmental Biology 2022-01-01
Coming Soon ...