A5102709659- Nitric Oxide and Endothelin Effects
- Ion Transport and Channel Regulation
- Adenosine and Purinergic Signaling
- Caveolin-1 and cellular processes
- Erythrocyte Function and Pathophysiology
- Heart Failure Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
- Peptidase Inhibition and Analysis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hypothalamic control of reproductive hormones
- Ovarian function and disorders
- Sodium Intake and Health
- Thermoregulation and physiological responses
- Cardiovascular Issues in Pregnancy
University of Iowa
2019-2021
Harry S. Truman Memorial Veterans' Hospital
2017
University of Missouri
2016-2017
University of Missouri Hospital
2015
Brigham and Women's Hospital
2014
The endothelium responds to numerous chemical and mechanical factors in regulating vascular tone, blood pressure, flow. endothelial volume-regulated anion channel (VRAC) has been proposed be mechanosensitive thereby sense fluid flow hydrostatic pressure regulate function. Here, we show that the leucine-rich repeat-containing protein 8a, LRRC8A (SWELL1), is required for VRAC human umbilical vein cells (HUVECs). Endothelial regulates AKT-endothelial nitric oxide synthase (eNOS) signaling under...
Directly observed treatment short-course (DOTS) strategy is an effective mode of treating TB. We aimed to study the cost effectiveness and patients' satisfaction with home based direct observation (DOT), innovative approach community-based DOT (CBDOT) hospital (HBDOT).A randomized controlled trial involving 150 newly diagnosed pulmonary TB patients in four clinics Ile Ife , Nigeria, was done. They were randomly assigned receive anti drugs for intensive phase administered at by a worker or...
Abstract The endothelium responds to a multitude of chemical and mechanical factors in regulating vascular tone, angiogenesis, blood pressure flow. endothelial volume regulatory anion channel (VRAC) has been proposed be mechano-sensitive, activate response fluid flow/hydrostatic putatively regulate reactivity angiogenesis. Here, we show that the Leucine Rich Repeat Containing Protein 8a, LRRC8a (SWELL1) functionally encodes VRAC human umbilical vein cells (HUVECs). Endothelial SWELL1...
Background: Purinergic receptor activation by extracellular nucleotides is involved in thrombosis and neointimal hyperplasia that accompany atherosclerosis postangioplasty restenosis. Human apyrases [ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDases)] are membrane bound enzymes hydrolyze nucleotides, thereby inhibiting purinergic activation. CD39, the first identified human apyrase, constitutively expressed on endothelial cell (EC) vascular smooth muscle (VSMC) surfaces. APT102, a...