Irene Chen

ORCID: 0000-0001-5470-655X
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About
Contact & Profiles
Research Areas
  • Testicular diseases and treatments
  • Sperm and Testicular Function
  • Hormonal and reproductive studies
  • Reproductive Biology and Fertility
  • Neuroblastoma Research and Treatments
  • Estrogen and related hormone effects
  • Pediatric Pain Management Techniques
  • Anesthesia and Pain Management
  • Opioid Use Disorder Treatment
  • Assisted Reproductive Technology and Twin Pregnancy
  • Menopause: Health Impacts and Treatments
  • Sarcoma Diagnosis and Treatment

University of Southern California
2020-2025

Keck Hospital of USC
2024-2025

649 Background: Both testicular (TGCT) and ovarian germ cell tumors (OGCT) originate from a common primordial lineage prior to differentiation into sperm or eggs share several features. While TGCT are extensively studied, less is known about OGCT but given the relative rarity of both OGCT, we aimed comprehensively assess current landscape these diseases using population-based cancer registries that surveil entire civilian population US. Importantly, this analysis includes all data 2000 2017...

10.1200/jco.2025.43.5_suppl.649 article EN Journal of Clinical Oncology 2025-02-10

The Early versus Late Intervention Trial with Estradiol demonstrated that hormone therapy (HT) reduces subclinical atherosclerosis progression in healthy postmenopausal women who initiated HT proximity to menopause (<6 years) but not those distant from menopause, (≥10 years). This analysis explores the role of serum sex steroid hormones and hormone-binding globulin (SHBG) progression, examining differences based on time since menopause. Post-trial analysis. study included 535 women; nearly...

10.1093/ejendo/lvaf032 article EN European Journal of Endocrinology 2025-02-20

502 Background: Testicular germ cell tumors (TGCTs) is the leading solid-organ malignancy of adolescent/young adult males. Incidence rising in all racial/ethnic groups, and most rapidly Hispanics, who tend to be younger than non-Hispanic white (NHW) patients at diagnosis yet have poorer survival. Understanding these disparities an urgent research priority, but granular prognostic information inadequate large population-based registries. We therefore initiated investigation a largely Hispanic...

10.1200/jco.2024.42.4_suppl.502 article EN Journal of Clinical Oncology 2024-01-29
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