A5035258004- Nuclear Structure and Function
- RNA regulation and disease
- RNA Research and Splicing
- Biochemical Analysis and Sensing Techniques
- Energy and Environment Impacts
- Endoplasmic Reticulum Stress and Disease
- Regulation of Appetite and Obesity
- Lipid metabolism and biosynthesis
- Agriculture Sustainability and Environmental Impact
- Mitochondrial Function and Pathology
- Olfactory and Sensory Function Studies
- Environmental Impact and Sustainability
Universidade de Santiago de Compostela
2016-2018
Center for Research in Molecular Medicine and Chronic Diseases
2016-2018
Type 1 and type 2 familial partial lipodystrophies (FPLD) are characterized by the loss or increase in subcutaneous fat certain body regions, as well metabolic disorders. Higher muscle volume mass have also been described. However, so far, possible bone involvement has not studied. The aim of this study was to evaluate mineral density (BMD) patients with FPLD.A total 143 women were selected distributed into three groups (17 FPLD2, 82 FPLD1 44 nonlipodystrophic obese female controls). A...
PELD (Progressive Encephalopathy with or without Lipodystrophy Celia's Encephalopathy) is a fatal and rare neurodegenerative syndrome associated the BSCL2 mutation c.985C>T, that results in an aberrant transcript exon 7 (Celia seipin). The aim of this study was to evaluate both process cellular senescence effect unsaturated fatty acids on preadipocytes from homozygous c.985C>T patient. Also, role seipin isoform adipogenesis studied adipose-derived human mesenchymal stem cells.Cellular...