A5062958344- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Pediatric Pain Management Techniques
- Obstructive Sleep Apnea Research
- Anesthesia and Sedative Agents
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Anesthesia and Pain Management
- Lysosomal Storage Disorders Research
- Antibiotics Pharmacokinetics and Efficacy
- Congenital Diaphragmatic Hernia Studies
- Adrenal Hormones and Disorders
- Electrolyte and hormonal disorders
- Restless Legs Syndrome Research
- Cancer, Hypoxia, and Metabolism
- Trypanosoma species research and implications
- Parkinson's Disease and Spinal Disorders
- Intraoperative Neuromonitoring and Anesthetic Effects
- Glioma Diagnosis and Treatment
- Pain Management and Opioid Use
- Medical History and Innovations
- Intraocular Surgery and Lenses
- Pharmacogenetics and Drug Metabolism
- Nausea and vomiting management
Starship Children's Health
2015-2022
Royal Manchester Children's Hospital
2006-2013
Great Ormond Street Hospital
1966-2000
University College London
1966-2000
Royal Children's Hospital
2000
Children with anterior mediastinal masses may experience serious complications during general anaesthesia. We retrospectively surveyed the records of children an mass who had been admitted to our hospital over a 7 year period. The presence pre-operative symptoms or signs, findings any special investigations performed and anaesthetic outcome were noted. All radiological studied tracheal compression measured. majority patients presented severe clinical signs. There was poor relationship...
Summary Codeine is frequently used for postoperative analgesia in children. Intramuscular injections are not ideal and the rectal route may be preferable. We compared intramuscular codeine administered following neurosurgery. 20 children (over 3 months) undergoing elective neurosurgical procedures, were randomized to receive either or phospate (1 mg·kg −1 ) at end of procedure. Serum levels morphine assayed intervals administration (0, 30, 60, 120, 240 min). Fentanyl was intraoperative...
The unbound and bound plasma concentration of bupivacaine in 50 infants less than 55 weeks postconceptual age was determined following combined spinal epidural anaesthesia (CSEA). Plasma concentrations were at 15‐min intervals up to 60 min postspinal anaesthesia. Maximum levels recorded between 45 post CSEA. Total above a toxic threshold level 4 μg·ml −1 4% patients 2.5 10% patients. Unbound greater presumed 0.25 16% cases 0.3 14% cases. A wide range protein binding measured (varying from...
The anesthetic management of pheochromocytoma has been based upon the intraoperative control blood pressure and fluid balance following adequate preoperative preparation. This can be difficult, especially in presence significant comorbidity such as cardiac or renal dysfunction. Two cases children with are reported where introperative were guided by measurement changes descending aortic flow using an esophageal Doppler probe. advantages a technique compared more invasive monitors discussed.
The case of a 6-year-old boy who developed complications following gastric interposition surgery for severe, recurrent esophageal stricture is reported. Investigation his pleural effusion revealed rare and unexpected complication.
Editor, Morquio disease is an inherited metabolic disorder from the family of lysosomal storage disorders called mucopolysaccharidoses (MPS).1–6 Each type MPS has enzyme defect that results in accumulation specific waste products metabolism glycosaminoglycans (GAGS). In (MPS IVa) absence galactosamine-6-sulfatase intracellular keratan sulfate and chondroitin-6-sulfate, leading to local cellular dysfunction, organomegaly multisystem dysfunction. IVa characterised by severe skeletal ligamental...
Hypotensive anaesthesia can be employed to improve the outcome in a variety of surgical procedures. Since there is no single agent capable safely and effectively lowering arterial pressure all situations, anaesthetist may need employ agents or techniques order achieve target pressure. This article considers currently available methods inducing hypotension their application safe conduct anaesthesia.