Antibacterial, anti-inflammatory, and pro-angiogenic properties are prerequisites for dressing materials that accelerate the healing process of infected wounds.

We aimed to develop an antioxidant dressing material with pro-angiogenic potential that could promote wound healing. Gelatin (Gel) was selected improve the biocompatibility of scaffolds, while graphene oxide (GO) added enhance their mechanical property. The loaded N-Acetyl cysteine (NAC) performing effect scavenging reactive oxygen species (ROS) at site.The physicochemical and properties, NAC releases, NAC-GO-Gel scaffolds were evaluated in vitro. regeneration capability systemically...

Background Cicatricial alopecia encompasses a diverse group of disorders characterized by the permanent destruction hair follicles and irreversible loss. Follicular unit transplantation was developed in 1994. However, large-scale clinical trials are necessary to study follicular for treating Chinese cicatricial patients. Objective To investigate efficacy treatment Methods Patients with were enrolled. The designated recipient area, density donor site, transplanted operative time recorded....

Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) are effective in the treatment of skin photoaging; however, their low yield and functional decline with passage progression limit clinical application. Cell-derived nanovesicles (CNVs) potential alternatives that can address limitations EVs MSCs conducive to transformations. Hair follicle (HFMSCs), a type MSCs, have demonstrated function repairing tissues; nevertheless, efficacy CNVs HFMSCs (HFMSC-CNVs) photoaging...

Platelet-rich plasma (PRP) is an autologous concentration of human platelets in plasma. In this paper, we aimed to investigate the effect PRP on hair growth. and platelet-poor were prepared by sterile centrifugation injected into shaved dorsal skin mice (n = 10). Saline injection was used control group. The length randomly plucked hairs measured at 8, 13, 18 days after injection. Histological examination preformed observe histologic changes skins. immunohistochemistry analysis CD31 performed...

This study was aimed to explore the effect of W-plasty combined Botox-A injection in improving appearance scar. According inclusive and exclusive criteria, patients received (study group) or traditional (control scar repairment were enrolled this study. After surgery, a follow-up ranged from 1 2 years conducted. The effectiveness surgery assessed by visual analogue scale (VAS). A total 38 study, including 21 cases group 17 control group. There no significant difference identified age (t =...

Objective. To investigate the effect and safety of PRP Yifu combined with ultrapulsed CO2 lattice laser in patients sunken acne scar. Methods. 700 subjects were selected from group scar treated our hospital November 2010 to December 2020. They divided into control (n = 350) study 350). The grouping was mainly based on random number table method. Patients ultrapulse laser, while those Yifu. clinical effect, improvement quality life before after treatment, adverse events during treatment...

Background Nowadays, people's pace of life continues to rapid up, and many bad habits will accelerate the aging eye periphery, patients with sunken upper eyelids are be found in younger people. In young Asians, single often accompanied by eyelid depression, so correcting depression during blepharoplasty becomes a higher challenge for plastic surgeons. Current surgical methods include three major categories: tissue repositioning, injection filling, combined use. According grades 1 2 mild or...

Abstract A series of novel 3,5‐dichloro‐4‐(1,1,2,2‐tetrafluoroethoxy)phenyl containing 4‐methyl‐1,2,3‐thiadiazole derivatives were designed and synthesized via Ugi reaction. Their structures confirmed by IR, 1 H NMR, 13 C NMR high‐resolution mass spectroscopy. The preliminary bioassay results indicated that some title compounds had good fungicide activity at 50 µg/mL; most the presented a certain degree direct inhibition activity, inactivation curative against tobacco mosaic virus 500 µg/mL...

Rationale: Aging of face is an unavoidable process. Traditional procedures for facial rejuvenation have multiple disadvantages. In this case report, we used innovative technique combining thread lift with small incision rhytidectomy rejuvenation. Management complication was also reported. Patient concerns: We presented a 52-year-old male ptosis and wrinkles. Diagnoses: The patient diagnosed as aging including skin laxity, mid-face mandibular jowl ptosis, static crows-feet wrinkles, deepening...

For extensive irregular cicatricial alopecia after burn, effective and pleasing restoration of hair-bearing scalp remains challenging. In this article, the authors presented staged reconstructive treatment for with goal to achieve better reliable results. A retrospective review performed in 16 patients burn was conducted. stage 1, final flaps were designed at 1st. Tissue expanders placed into subgaleal plane serially inflated normal saline. 2, scarring tissues excised expanded advanced...

Information release is a key to the macro-economy during outbreak of Coronavirus Diosease-2019 (COVID-19). To explore relationship between information supply by government and public demand in pandemic, this study collected over 4,000 posts published on most popular social media platform, i.e., WeChat. Many approaches, such as text mining, are employed at different stages pandemic. According results, attached great importance related The main topics released included latest situation...

Background We aimed to study the effect of tetramethylpyrazine/ligustrazine (TMP) on survival rate adipose-derived stem cell (ADSC) transplantation. Methods Human ADSCs were cultured and subcultured. Detection growth was performed using CCK8 kit. A total 12 BALB/c nude mice including 4 groups (group 1: ADSC–hyaluronic acid [HA] + phosphate-buffered saline [PBS]; group 2: ADSC-HA TMP injection; 3: soaking; 4: injection soaking) used for animal experiments. Furthermore, hematoxylin-eosin...

High levels of VEGF and excessive angiogenesis contribute significantly to hypertrophic scar (HS) formation. Our study aimed preliminarily investigate the effect axitinib, a selective receptor tyrosine kinase inhibitor, on HS explore its possible mechanism in rabbit ear model.Ten male New Zealand white rabbits were used establish models then randomised control axitinib groups. The tissues two groups injected with or normal saline, they evaluated after one month treatment. Macroscopic...

摘要: 近年来直播水稻在江苏等地区扩展迅速,但其栽培和育种的专项研究很少。本研究对江苏省苏中地区直播稻生产力水平进行了调查,在此基础上进一步实施水稻直播栽培模式下氮肥施用量和运筹比例试验,探讨直播水稻群体生长和产量形成对氮肥施用的反应特征。调查结果显示,苏中地区普通农户直播水稻的产量平均为7 710 kg hm-2,显著低于机插和人工移栽稻,直播稻氮肥施用量一般在270 N hm-2之上,氮肥不合理施用的现象普遍存在。小区试验表明,施氮量和氮肥运筹比例均对直播稻产量有显著影响,氮肥施用量主要通过有效穗数和每穗粒数对产量发挥作用,而氮肥运筹比例主要对每穗粒数产生影响。在本试验条件下,氮肥施用量270 hm-2,基肥∶分蘖肥∶穗肥=4∶3∶3的产量最高。在上述施肥条件下,直播水稻群体结构较为合理,个体和群体的物质生产量均处于较高水平,结实期物质生产能力较强,经济系数表现合理的较高水平(0.53左右),同时有相对较好的抗倒性能。对直播水稻的增产途径和高产群体特征进行了较深入的讨论。

Beijing Synchrotron Radiation Facility is a partly dedicated synchrotron radiation source operated in either parasitic or mode. The 3B1A beamline, extracted from bending magnet, was originally designed as soft x-ray beamline for submicro lithography with critical lateral size just below 1μm 1988 and no change has been made since it built. But later the required resolution of changed sub-micrometre to nanometre size. This can longer more meet requirement nano be modified fit purpose.

Abstract Background Radiation-induced injuries (RII) mainly result from reactive oxygen species (ROS), which are harmful compounds that can damage DNA. Asiaticoside (AC), one of the main functional components extracted Centella asiatica, has potent pharmacological effects such as anti-inflammatory and anti-oxidant activity. However, its role in RII remains unclear. Purpose The purpose current study is to investigate whether AC mitigate vitro vivo . Material Methods Cell model was...

Background: Kartogenin is a heterocyclic compound able to promote the proliferation, migration, and differentiation of various cell types induce cartilage-like tissue regeneration. However, role kartogenin in hair follicles (HFs), remains unknown. We therefore investigated effects on regulation growth cycle transition. Methods: The status, migration primary human outer root sheath cells (ORSCs) were evaluated by MTS assay, flow cytometry, Transwell® scratch assays, respectively. exposed...

Objective Our research was carried out to provide a clinical reference for the application of nonsurgical therapy in newborns with congenital auricular deformities east China. Methods A retrospective study consecutive using noninvasive ear molding conducted Hangzhou China's Zhejiang Province. The demographic and information photographs before after treatment were taken. diagnosis each deformity identified, outcome evaluated. Results total 224 patients including 356 anomalies received...