Inge A. Ivens

ORCID: 0000-0001-5506-363X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Hemophilia Treatment and Research
  • Toxic Organic Pollutants Impact
  • Carcinogens and Genotoxicity Assessment
  • Monoclonal and Polyclonal Antibodies Research
  • Blood Coagulation and Thrombosis Mechanisms
  • Biosimilars and Bioanalytical Methods
  • Protein purification and stability
  • Pesticide Exposure and Toxicity
  • Pharmacology and Obesity Treatment
  • Cancer Research and Treatments
  • Plant-based Medicinal Research
  • Immunotoxicology and immune responses
  • Blood transfusion and management
  • Platelet Disorders and Treatments
  • CAR-T cell therapy research
  • Nanoparticle-Based Drug Delivery
  • Forensic Toxicology and Drug Analysis
  • Transgenic Plants and Applications
  • Alcohol Consumption and Health Effects
  • Environmental Toxicology and Ecotoxicology
  • 3D Printing in Biomedical Research
  • Poisoning and overdose treatments
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Blood groups and transfusion
  • Toxin Mechanisms and Immunotoxins

Bayer (United States)
1998-2019

Bayer (Germany)
1989-1993

A set of four learning and memory tests (Morris Maze I for reference memory, Morris II working one-way active avoidance, passive avoidance) were employed to address the questions whether parathion impaired cognitive functions after low, long-term exposure could cause persistent changes in cognition. Motor activity general behavior investigated a functional observational battery. Parathion was administered rat food low doses which caused no clinical symptoms or borderline brain...

10.1093/toxsci/46.1.101 article EN Toxicological Sciences 1998-01-01

10.1016/0892-0362(90)90077-p article EN Neurotoxicology and Teratology 1990-11-01

BAY 94-9027 (Jivi) is a site-specifically PEGylated human B-domain-deleted (BDD) recombinant factor VIII (FVIII), with 60 kDa branched PEG molecule attached. The nonclinical safety of was evaluated in toxicology program that included 2 weeks intravenous (IV) toxicity studies rats and rabbits, juvenile study as well 26-week chronic rats. Doses 75, 750, or 2250 IU/kg given every other day for did not elicit any findings related to 94-9027. Specifically, no thrombus formation histological...

10.1177/0192623319852300 article EN cc-by-nc Toxicologic Pathology 2019-05-27
Coming Soon ...