A5070976984- Advanced NMR Techniques and Applications
- Solid-state spectroscopy and crystallography
- Electron Spin Resonance Studies
- Nuclear Physics and Applications
- Atomic and Subatomic Physics Research
- Nuclear physics research studies
- Magnetism in coordination complexes
- Particle accelerators and beam dynamics
- Synthesis and Properties of Aromatic Compounds
- Radiation Therapy and Dosimetry
- Quantum Chromodynamics and Particle Interactions
- Superconducting Materials and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Organic and Molecular Conductors Research
- Particle Accelerators and Free-Electron Lasers
- NMR spectroscopy and applications
- Advanced Chemical Physics Studies
- Inorganic Fluorides and Related Compounds
- Textile materials and evaluations
- Diamond and Carbon-based Materials Research
- Force Microscopy Techniques and Applications
- Dark Matter and Cosmic Phenomena
- Radiation Detection and Scintillator Technologies
- Crystallography and Radiation Phenomena
- Photocathodes and Microchannel Plates
RIKEN
2018-2025
RIKEN Nishina Center
2013-2023
Pioneer (Japan)
2019-2023
Osaka University
2010-2014
Anan National College of Technology
2010
Sanyo (Japan)
2005
Dynamic nuclear polarization (DNP), a means of transferring spin from electrons to nuclei, can enhance the (hence NMR sensitivity) in bulk materials at most 660 times for (1)H spins, using electron spins thermal equilibrium as polarizing agents. By photo-excited triplet states instead, DNP overcome above limit. We demonstrate 34%, which gives an enhancement factor 250,000 0.40 T, while maintaining sample (∼ 0.6 mg, ∼ 0.7 × 1 mm(3)) containing >10(19) room temperature. Room temperature...
Singlet fission (SF), converting a singlet excited state into spin-correlated triplet-pair state, is an effective way to generate spin quintet in organic materials. Although its application photovoltaics as exciton multiplier has been extensively studied, the use of unique degree freedom largely unexplored. Here, we demonstrate that polarization multiexcitons generated by SF improves sensitivity magnetic resonance water molecules through dynamic nuclear (DNP). We form supramolecular...
Triplet dynamic nuclear polarization (triplet-DNP) is a technique that can obtain high under moderate conditions. However, in order to practically useful polarization, large single crystals doped with polarizing agent must be strictly oriented respect the magnetic field sharpen electron spin resonance (ESR) spectra, which fatal problem prevents its application truly biomolecular targets. Instead of this conventional physical approach controlling crystal orientation, here, we propose chemical...
Triplet dynamic nuclear polarization (triplet-DNP), a method to enhance magnetic resonance (NMR) and imaging (MRI) sensitivity using photoexcited triplet electrons, has great potential hyperpolarize spins at room temperature. Since the first report of room-temperature triplet-DNP in 1990, pentacene been only best option polarizing agent. However, poor air stability severely limited applicability triplet-DNP. We example agents with significant as well high ability comparable pentacene. The...
Dissolution dynamic nuclear polarization (DNP) has recently gained attention as a method to enhance the sensitivity of liquid NMR spectroscopy and MRI. We demonstrate dissolution sample hyperpolarized by DNP using photoexcited triplet electrons in 0.38 T at room temperature. The achieved 0.8% is 6100 times high that thermal equilibrium under condition. result an important step for become widely used chemical biomedical research.
While dynamic nuclear polarization based on photoexcited triplet electrons (triplet-DNP) has the potential to hyperpolarize spins of target substrates in low magnetic field at room temperature, there been no triplet-DNP system offering structural rigidity and substrate accessibility. Here, we report first example nanoporous metal–organic frameworks. Accommodation a carboxylate-modified pentacene derivative partially deuterated ZIF-8 (D-ZIF-8) results clear 1H NMR signal enhancement over...
The first example of triplet dynamic nuclear polarization crystalline ice is demonstrated by developing a water-soluble polarizing agent.
Dynamic nuclear polarization utilizing photoexcited triplet electrons (triplet-DNP) has great potential for room-temperature hyperpolarization of spins. However, the transfer to molecules interest remains a challenge due fast spin relaxation and weak interaction with target at room temperature in conventional host materials. Here, we demonstrate first example DNP guest porous material around by induced-fit-type structural transformation crystalline yet flexible metal-organic framework (MOF)....
Triplet dynamic nuclear polarization (triplet-DNP) achieves spin at moderate temperatures by using of photoexcited triplet electrons. The applications triplet-DNP for biomolecules have been hampered because acenes, the only polarizing agents used so far, tend to aggregate and lose their in biomolecular matrices. Here, we report first time use porphyrins as propose a new concept aggregation-tolerant agents. Sodium salts tetrakis(4-carboxyphenyl)porphyrin (TCPPNa) can be dispersed amorphous...
Utilizing photoexcited triplet electrons, dynamic nuclear polarization (DNP) has achieved, in a glassy matrix at 0.40 T and 120 K, 1H spin of 1.45 %, which is 4250 times larger than the thermal polarization. In matrix, various molecules interest, including 2,3,4-trifluorobenzoic acid 5-fluorouracil can be co-doped with polarizing agents; these co-dopants DNP was also successful.
Polarized electron spins in photoexcited triplet states enable dynamic nuclear polarization (DNP) at high temperatures, leading to increased sensitivity magnetic resonance imaging (MRI). For a practical of 10%, single crystals must be precisely oriented field generate spin resonances narrow range that satisfies conditions for transfer. However, this is not realistic medical applications. Substituted fullerenes as polarizing agents have enabled 1H polarizations above even random molecular...
Dynamic nuclear polarization (DNP) using transient electron spin generated by photoexcitation can improve magnetic resonance (NMR) sensitivity far beyond the thermal equilibrium limit for analysis in life science and drug discovery. However, DNP of liquid water at room temperature remains an important challenge. Here, we propose a new method called hyperpolarization relay, which nonequilibrium spins is transferred to proton nanocrystals then bulk water. Molecular doped with polarizing agent...
The generation of spin polarization is key in quantum information science and dynamic nuclear polarization. Polarized electron spins with long spin–lattice relaxation times (T1) at room temperature are important for these applications but have been difficult to achieve. We report the realization spin-polarized radicals extremely T1 a metal–organic framework (MOF) which azaacene chromophores densely integrated. Persistent generated MOF by charge separation after photoexcitation. Spin triplet...
Dynamic electron polarization (DEP), induced by quenching of photoexcited species stable radicals, can hyperpolarize spins in solution at room temperature. Recently, development technologies based on spin such as dynamic nuclear (DNP) has been progressing, where it is important to design molecules that achieve long-lasting DEP addition high DEP. Hybridization linking dyes and radicals a promising approach for efficient DEP, but strong interactions between neighboring often result the rapid...
Dynamic nuclear polarization with photo-excited triplet electrons (Triplet-DNP) is demonstrated using 6,13-diphenylpentacene (DPPentacene). DPPentacene soluble in various organic solvents, while pentacene, which used most of the triplet-DNP experiments, has limited solubility. An enhancement factor 81 obtained for 1H spins glass ethanol-d6 : water = 80 20 (w/w) doped 0.1 mM at 90 K 0.67 T.
Room-temperature triplet dynamic nuclear polarization (triplet-DNP) of nanocrystals dispersed in water is achieved for the first time.
The spin-polarized triplet state generated by light irradiation has potential for applications such as dynamic nuclear polarization (triplet-DNP). Recently, we have reported free-base porphyrins versatile and biocompatible polarizing agents triplet-DNP. However, the electron of is not very high, dilemma that high metalloporphyrins accompanied a too short spin–lattice relaxation time to be used We report here introduction electron-withdrawing fluorine groups into Zn enables long enough (>1...
We propose a scalable and practical implementation of spin amplification which does not require individual addressing nor specially tailored network. have demonstrated gain 140 in solid-state nuclear system the polarization has been increased to 0.12 using dynamic with photoexcited triplet electron spins. Spin higher opens door single measurement for readout quantum computers as well applications magnetic resonance spectroscopy infinitesimal samples concealed by thermal noise.
Formation of supramolecular complexes with cyclodextrins improves the dispersibility pentacene derivatives in polar matrices, resulting first triplet dynamic nuclear polarization an important bioprobe, pyruvate.
Photoangeregte Triplettelektronen ermöglichten in einer Glasmatrix bei 0.40 T und 120 K eine dynamische Kernpolarisation (DNP), die 4250-mal größere 1H-Spinpolarisation als unter thermischen Bedingungen ergab. Interessierende Moleküle wie 2,3,4-Trifluorbenzoesäure 5-Fluoruracil können der mit polarisierenden Reagentien codotiert werden, Polarisierung dieser Co-Dotanden DNP gelang ebenfalls. As a service to our authors and readers, this journal provides supporting information supplied by the...
In dynamic nuclear polarization (DNP) experiments applied to organic solids for creating nonequilibrium, high (1)H spin polarization, an efficient buildup of is attained by partially deuterating the material interest with appropriate concentration. such a dilute system, it shown that diffusion rate and thereby efficiency can further be enhanced continually applying radiofrequency irradiation deuterium decoupling during DNP process. As experimentally confirmed in this work, electron...
Differential cross sections of |$p$|–|$\mathrm{^6He}$| elastic scattering were measured in inverse kinematics at an incident energy 200 |$A \mathrm{MeV}$|, covering the high momentum transfer region 1.7–2.7 |$\mathrm{fm^{-1}}$|. The sensitivity low and transfers to density distribution was investigated quantitatively using relativistic impulse approximation calculations. In region, where present data taken, differential section has order magnitude higher inner part |$\mathrm{^6He}$|...
The lifetimes and spin–lattice relaxation time of photo-excited triplet electron pentacene doped in p-terphenyl at room temperature have been investigated. Values previously reported ESR studies are inconsistent with each other. In this paper, we determined these constants based on proton signals enhanced by dynamic nuclear polarization using the electrons (Triplet-DNP). combined analysis dependences signal intensities delay transfer laser pulse structure allows us to disentangle...