A5083496196- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Advanced NMR Techniques and Applications
- Soft Robotics and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Surgical Simulation and Training
- Electrospun Nanofibers in Biomedical Applications
- Moyamoya disease diagnosis and treatment
- Solid-state spectroscopy and crystallography
- Aortic aneurysm repair treatments
- Tissue Engineering and Regenerative Medicine
- Electron Spin Resonance Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Quantum Computing Algorithms and Architecture
- Quantum Information and Cryptography
- Acute Ischemic Stroke Management
- Meningioma and schwannoma management
- Teleoperation and Haptic Systems
- Anatomy and Medical Technology
- 3D Printing in Biomedical Research
- Cardiovascular Health and Disease Prevention
- Aortic Disease and Treatment Approaches
- Neurosurgical Procedures and Complications
- Atomic and Subatomic Physics Research
Osaka University
2015-2025
National Institutes for Quantum Science and Technology
2020-2024
Quantum (Australia)
2024
Japan Science and Technology Agency
2009-2022
Ichinomiya Kenshin College
2015-2021
Nishijin Hospital
2018
The University of Tokyo
2015-2017
Neurological Surgery
2015
Hokkaido University
2015
NTT Medical Center
2015
We propose a classical-quantum hybrid algorithm for machine learning on near-term quantum processors, which we call circuit learning. A driven by our framework learns given task tuning parameters implemented it. The iterative optimization of the allows us to circumvent high-depth circuit. Theoretical investigation shows that can approximate nonlinear functions, is further confirmed numerical simulations. Hybridizing low-depth and classical computer learning, proposed paves way toward...
Dynamic nuclear polarization (DNP), a means of transferring spin from electrons to nuclei, can enhance the (hence NMR sensitivity) in bulk materials at most 660 times for (1)H spins, using electron spins thermal equilibrium as polarizing agents. By photo-excited triplet states instead, DNP overcome above limit. We demonstrate 34%, which gives an enhancement factor 250,000 0.40 T, while maintaining sample (∼ 0.6 mg, ∼ 0.7 × 1 mm(3)) containing >10(19) room temperature. Room temperature...
$Q\phantom{\rule{0}{0ex}}u\phantom{\rule{0}{0ex}}a\phantom{\rule{0}{0ex}}n\phantom{\rule{0}{0ex}}t\phantom{\rule{0}{0ex}}u\phantom{\rule{0}{0ex}}m$ $r\phantom{\rule{0}{0ex}}e\phantom{\rule{0}{0ex}}s\phantom{\rule{0}{0ex}}e\phantom{\rule{0}{0ex}}r\phantom{\rule{0}{0ex}}v\phantom{\rule{0}{0ex}}o\phantom{\rule{0}{0ex}}i\phantom{\rule{0}{0ex}}r$...
In this paper, we propose a new prototype model of serial-parallel type active micro catheter (MAC) with two bending degrees freedom. It is 4 Fr, 5 Fr and 6 (1 Fr=1/3 mm) in diameter consist 3 units incorporating SMA wires lumina as the servo actuator. The motion, direction angle MAC have been measured by application electricity air physiological saline solution. We also modeled MAC. Experimental results show that reasonable for practical applications. By using simulators (conditions similar...
Minimum invasive surgery that supports doctors and reduces patient's physical pain has attracted attention. We consider a new intravascular neurosurgery system. There are two problems in neurosurgery: one is doctor's exposure to x-ray, another the lack of skilled doctors. developed remote control system by using master-slave solve these problems. In this paper, we describe development slave device construct catheter operation with safety. To overcome some encountered on previous (2000),...
In this paper, we propose a new prototype model of micro-catheter with active guide wire that has two bending degrees freedom. The design and fabrication methods micro catheters (MAC) are described. Prototype models 3Fr, 4Fr, 6Fr (1Fr=1/3 mm) in diameter consist catheter tube ionic conducting polymer film actuator on its front end as the servo actuator. characteristics MAC have been measured by application electricity physiological saline solution. We also modeled for characteristic...
Background: Computer-based simulation is necessary to clarify the hemodynamics in brain aneurysm. Specifically for endovascular treatments, effects of indwelling intravascular devices on blood stream need be considered. The most recent technology used cerebral aneurysm treatment related use flow diverters reduce amount entering To verify differences reduction, we analyzed multiple Enterprise stents and two kinds diverters. Materials Methods: In this research, virtually modeled three...
<h3>Objectives:</h3> The aim of this study was to identify risk factors for rupture unruptured cerebral aneurysms (UCAs) in elderly Japanese patients aged 70 years or older. <h3>Methods:</h3> participants included all age older 3 prospective studies Japan (the Unruptured Cerebral Aneurysm Study [UCAS Japan], UCAS II, and the at Jikei University School Medicine). A total 1,896 with 2,227 UCAs were investigated. median mean follow-up periods 990 802.7 days, respectively. <h3>Results:</h3>...
We employ so-called quantum kernel estimation to exploit complex dynamics of solid-state nuclear magnetic resonance for machine learning. propose map an input a feature space by input-dependent Hamiltonian evolution, and the is estimated interference evolution. Simple learning tasks, namely one-dimensional regression tasks two-dimensional classification are performed using proton spins which exhibit correlation over 10 spins. also numerical simulations evaluate performance without noise...
We propose a method for learning temporal data using parametrized quantum circuit. use the circuit that has similar structure as recurrent neural network, which is one of standard approaches employed this type machine task. Some qubits in are utilized memorizing past data, while others measured and initialized at each time step obtaining predictions encoding new input datum. The proposed approach utilizes tensor product to get nonlinearity with respect inputs. Fully controllable, ensemble...
Solution-state nuclear magnetic resonance spectroscopy (NMR) is a powerful method for the analysis of intermolecular interactions within biomolecular system. However, low sensitivity one major obstacles NMR. We improved solution-state 13C NMR observation between protein and ligand using hyperpolarized solution samples at room temperature. Eutectic crystals composed 13C-salicylic acid benzoic doped with pentacene were by dynamic polarization photoexcited triplet electrons, 0.72 ± 0.07% was...
Abstract Background In order to reduce fluoroscope usage in endovascular surgery, there is a need develop autonomous catheter insertion systems. Methods We propose system for tracking the position and speed of using magnetic motion capture sensor provide feedback catheter‐driving mechanism, perform major vasculature. Catheter control path reconstruction experiments were performed with inside silicone model vasculature simulate surgery. Results The controlled speeds 6.14 mm/s reproduced...
The clinical presentations, findings of neuroradiological examinations, laboratory findings, pathological diagnoses, methods treatment, and results follow-up 43 cases pineal tumor collected at the Nagoya University Hospital from 1958 to 1979 are reviewed. definitions calcification body given. There is a significant difference in incidence between teratomas germinomas. Although there 100% rate germinoma, very low teratoma; appears only small percentage teratoma mixed with germinoma or...
Dissolution dynamic nuclear polarization (DNP) has recently gained attention as a method to enhance the sensitivity of liquid NMR spectroscopy and MRI. We demonstrate dissolution sample hyperpolarized by DNP using photoexcited triplet electrons in 0.38 T at room temperature. The achieved 0.8% is 6100 times high that thermal equilibrium under condition. result an important step for become widely used chemical biomedical research.
OBJECTIVE: To revascularize ischemic territories of both the anterior cerebral artery(ACA) and middle artery (MCA), a simple effective combined bypass operation was performed in 36 pediatric patients with moyamoya disease during past 8 years. METHODS: The branches superficial temporal (STA) were used to ACA MCA territories. In children older than 5 years, parietal branch STA usually for an end side anastomosis cortical MCA. who younger encephaloduroarteriosynangiosis instead direct...
A 34-year-old woman with primary choroid plexus papilloma occurring in the suprasellar region is reported. No connection ventricular system was found during intraoperative observations. The findings of pathological examinations such as hematoxylin and eosin staining, transthyretin (prealbumin) immunoreactivity, electron microscopy were consistent papilloma. Radiologically, it extremely difficult to differentiate from tuberculum sellae meningioma. To our knowledge, this first case location...
We propose an in vitro patient-specific anatomical model of the human cerebral artery and its simulation endovascular intervention, a potent treatment modality for cerebrovascular diseases. Our proposed reproduces 3-dimensional vasculature lumen, using computed tomography (CT) magnetic resonance (MR) fluoroscopic information, within thin artery-like membranous configuration having material properties close to arterial tissue. This exceedingly realistic surgical feel, dynamic vascular...
In this paper, we propose an in vitro patient-tailored biological model of human cerebral artery, innovative platform for simulating intravascular neurosurgery to evaluate medical robots and devices. This anatomically accurate reproduces 3-dimensional configuration individual arteries with artery-like thin membranous structure made silicone elastomer. Its modeling resolution is 13 /spl mu/m. Presented methodology also allows constructing any hollow structure, which suitable robot...
Abstract Background Quantification of medical skills is a challenge, particularly simulator‐based training. In the case endovascular intervention, it desirable that simulator accurately recreates morphology and mechanical characteristics vasculature while enabling scoring. Methods For this purpose, we propose cyber‐physical system composed optical sensors for catheter's body motion encoding, magnetic tracker capture an operator's hands, opto‐mechatronic measuring interaction catheter tip...
Utilizing photoexcited triplet electrons, dynamic nuclear polarization (DNP) has achieved, in a glassy matrix at 0.40 T and 120 K, 1H spin of 1.45 %, which is 4250 times larger than the thermal polarization. In matrix, various molecules interest, including 2,3,4-trifluorobenzoic acid 5-fluorouracil can be co-doped with polarizing agents; these co-dopants DNP was also successful.