A5054763394- Multisensory perception and integration
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Ophthalmology and Visual Impairment Studies
- Neurological disorders and treatments
- Tactile and Sensory Interactions
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Glaucoma and retinal disorders
- Olfactory and Sensory Function Studies
- Genetic Neurodegenerative Diseases
- Autism Spectrum Disorder Research
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Neuroscience and Music Perception
- Motor Control and Adaptation
- Parkinson's Disease Mechanisms and Treatments
- Vestibular and auditory disorders
- Neuroscience and Neural Engineering
- Antioxidant Activity and Oxidative Stress
- Differential Equations and Numerical Methods
- Advanced Numerical Methods in Computational Mathematics
- Genetics and Neurodevelopmental Disorders
Albert Einstein College of Medicine
2012-2024
Trinity College Dublin
2002-2024
Montefiore Medical Center
2015-2024
Sligo University Hospital
2024
Technological University Dublin
2018-2024
Temple Street Children's University Hospital
2021
Toronto Rehabilitation Institute
2020
University Health Network
2020
University of Toronto
2020
California Baptist University
2019
Congruent audiovisual speech enhances our ability to comprehend a speaker, even in noise-free conditions. When incongruent auditory and visual information is presented concurrently, it can hinder listener's perception cause him or her perceive that was not either modality. Efforts investigate the neural basis of these effects have often focused on special case discrete syllables are spatially temporally congruent, with less work done natural, continuous speech. Recent electrophysiological...
Successful integration of auditory and visual inputs is crucial for both basic perceptual functions higher-order processes related to social cognition. Autism spectrum disorders (ASD) are characterized by impairments in cognition associated with abnormalities sensory processes. Several groups have reported that individuals ASD impaired their ability integrate socially relevant audiovisual (AV) information, it has been suggested this contributes the cognitive deficits observed ASD. However,...
Self-motion through an environment involves a composite of signals such as visual and vestibular cues. Building upon previous results showing that combine in statistically optimal fashion, we investigated the relative weights cues during self-motion. This experiment was comprised three experimental conditions: alone, alone (with four different standard heading values), visual–vestibular combined. In combined cue condition, inter-sensory conflicts were introduced (Δ = ±6° or ±10°)....
The simultaneous presentation of a stimulus in one sensory modality often enhances target detection another modality, but the neural mechanisms that govern these effects are still under investigation. Here, we test hypothesis proposed neurophysiological literature: auditory facilitation visual-target operates through cross-sensory phase reset ongoing oscillations (Lakatos et al., 2009). To date, measurement limitations have prevented this potentially powerful mechanism from being directly...
Even simple tasks rely on information exchange between functionally distinct and often relatively distant neuronal ensembles. Considerable work indicates oscillatory synchronization through phase alignment is a major agent of inter-regional communication. In the brain, different phases correspond to low- high-excitability states. Optimally aligned (or states) promote Studies have also shown that sensory stimulation can modulate or reset ongoing cortical oscillations. For example, auditory...
Clinical relevance This study demonstrates an association between myopia and smartphone data usage. Youths now spend more time participating in near tasks as a result of poses additional risk factor for development/progression is important research question relation to potential management strategies.Background Children are exposed another possible environmental – smartphones. investigates the amount students on their smartphones patterns usage from perspective.Methods Primary, secondary...
Abstract Purpose The Myopia Outcome Study of Atropine in Children (MOSAIC) is an investigator‐led, double‐masked, randomized controlled trial investigating the efficacy and safety 0.01% atropine eye drops for managing myopia progression a predominantly White, European population. Methods aged 6–16 years with were randomly allocated 2:1 to nightly or placebo both eyes 2 years. primary outcome was cycloplegic spherical equivalent (SE) at 24 months. Secondary outcomes included axial length (AL)...
Background Adult onset idiopathic isolated focal dystonia presents with a number of phenotypes. Reported prevalence rates vary considerably; well‐characterized cohorts are important to our understanding this disorder. Aim To perform nationwide epidemiological study adult in the Republic Ireland. Methods Patients were recruited from multiple sources. Diagnosis was based on assessment by neurologist an expertise movement disorders. When consent obtained, clinical features including family...
Abstract Purpose With the increasing prevalence in myopia there is growing interest active prevention. This study aims to increase our understanding of parental attitudes development and control, as a means inform future health planning policy. It evaluates, for first time, attitude parents its associated risks, well assessing exposure Irish children environmental factors that may influence their risk profile development. Methods Parents 8–13 year old eight participating schools completed...
An emerging neuropathological theory of Autism, referred to here as "the neural unreliability thesis," proposes greater variability in moment-to-moment cortical representation environmental events, such that the system shows general instability its impulse response function. Leading evidence for this thesis derives from functional neuroimaging, a methodology ill-suited detailed assessment sensory transmission dynamics occurring at millisecond scale. Electrophysiological assessments thesis,...
The frequency of environmental vibrations is sampled by two the major sensory systems, audition and touch, notwithstanding that these signals are transduced through very different physical media entirely separate epithelia. Psychophysical studies have shown manipulating in or touch can a significant cross-sensory impact on perceived other system, pointing to intimate links between senses during computation frequency. In this regard, vibratory event be thought as multisensory perceptual...
This paper discusses the technical issues that were required to adapt a KUKA Robocoaster for use as real-time motion simulator. Within this context, addresses physical modifications and software control structure needed have flexible safe experimental setup. It also delays transfer function of system. The is divided into two sections. first section describes safety structures MPI Motion Simulator. second shows measurements latencies frequency responses results show Simulator compare...
Certain features of objects or events can be represented by more than a single sensory system, such as roughness surface (sight, sound, and touch), the location speaker (audition sight), rhythm duration an event (by all three major systems). Thus, these properties said to sensory-independent amodal. A key question is whether common multisensory cortical regions process amodal features, does each system contain its own specialized region(s) for processing features? We tackled this issue...
Abstract Self-motion through an environment stimulates several sensory systems, including the visual system and vestibular system. Recent work in heading estimation has demonstrated that cues are typically integrated a statistically optimal manner, consistent with Maximum Likelihood Estimation predictions. However, there been some indication cue integration may be affected by characteristics of stimulus. Therefore, current experiment evaluated whether presenting optic flow stimuli...