Krithika Murali

ORCID: 0000-0001-5581-2039
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About
Contact & Profiles
Research Areas
  • Healthcare professionals’ stress and burnout
  • Advances in Oncology and Radiotherapy
  • Cancer Genomics and Diagnostics
  • COVID-19 and healthcare impacts
  • Ovarian cancer diagnosis and treatment
  • Testicular diseases and treatments
  • Pancreatic and Hepatic Oncology Research
  • Innovations in Medical Education
  • Genomic variations and chromosomal abnormalities
  • Prenatal Screening and Diagnostics
  • Health and Medical Research Impacts
  • COVID-19 and Mental Health
  • Genomics and Rare Diseases
  • Health Systems, Economic Evaluations, Quality of Life
  • Paleopathology and ancient diseases
  • Cervical Cancer and HPV Research
  • Colorectal Cancer Screening and Detection
  • Gestational Trophoblastic Disease Studies
  • COVID-19 epidemiological studies
  • Defense, Military, and Policy Studies
  • Operations Management Techniques
  • Advanced Manufacturing and Logistics Optimization
  • Economic and Financial Impacts of Cancer
  • BRCA gene mutations in cancer
  • Vaccine Coverage and Hesitancy

Victorian Clinical Genetics Services
2021-2025

Royal Children's Hospital
2021-2025

Murdoch Children's Research Institute
2021-2025

Royal Marsden NHS Foundation Trust
2018-2022

Royal Marsden Hospital
2018-2022

Austin Health
2019-2021

Austin Hospital
2020

Institute of Cancer Research
2018

Cornell University
2018

Memorial Sloan Kettering Cancer Center
2018

•This is the first global report of well-being in oncology professionals since coronavirus disease 2019 (COVID-19) pandemic.•In this survey 1520 professionals, 67% reported a change professional duties COVID-19.•About 25% had risk distress (poor well-being), 38% felt burnout, and 66% were not able to perform their job compared with pre-COVID-19 period.•Well-being performance COVID-19 (JP-CV) correlated crude mortality rate country practice.•The main predictors well-being, JP-CV resilience...

10.1016/j.esmoop.2021.100058 article EN cc-by-nc-nd ESMO Open 2021-02-06

•Risk of distress/burnout amongst oncology professionals continues to worsen since COVID-19 despite improved job performance.•Female and younger (≤40 years old) colleagues continue be at higher risk poor well-being feeling burnout.•Job demands have increased, with nearly half now overwhelmed workload.•Concerns regarding career development/training, security, international fellowship opportunities remain high.•A quarter reported considering changing their career, including leaving the...

10.1016/j.esmoop.2021.100374 article EN cc-by-nc-nd ESMO Open 2021-12-17

The European Society for Medical Oncology (ESMO) Resilience Task Force (RTF) was established to address burnout and well-being issues among oncology professionals. In this article, we present findings on shared perceptions recommendations support improve professionals' health at work. Inductive thematic analysis of qualitative responses from three global ESMO RTF surveys (2020-2021) conducted using Braun Clarke's six-step approach. Open-ended questions elicited suggestions, including...

10.1016/j.esmoop.2025.104298 article EN cc-by-nc-nd ESMO Open 2025-03-01

The COVID-19 pandemic has resulted in significant changes to professional and personal lives of oncology professionals globally. European Society for Medical Oncology (ESMO) Resilience Task Force collaboration aimed provide contemporaneous reports on the impact lived experiences well-being oncology.This online anonymous survey (July-August 2020) is second a series global surveys launched during course pandemic. Longitudinal key outcome measures including well-being/distress (expanded...

10.1016/j.esmoop.2021.100199 article EN cc-by-nc-nd ESMO Open 2021-07-01

Abstract We aimed to determine whether SNP-microarray genomic testing of saliva had a greater diagnostic yield than blood for pathogenic copy number variants (CNVs). selected patients who underwent CMA both and from 23,289 21,857 samples. Our cohort comprised 370 individuals both, 224 with syndromic intellectual disability (ID) 146 isolated ID. Mosaic CNVs or aneuploidy were detected in but not 20/370 (4.4%). All 20 ID, accounting 9.1% the ID sub-cohort. Pathogenic large size (median 46 Mb),...

10.1038/s41431-022-01232-5 article EN cc-by European Journal of Human Genetics 2022-11-29

The Australian Pancreatic Cancer Screening Program (APCSP) offers endoscopic ultrasound surveillance for individuals at increased risk of pancreatic ductal adenocarcinoma (PDAC) with all participants requiring assessment by a Familial Service before or after study enrolment. Individuals aged 40-80 years (or 10 younger than the earliest PDAC diagnosis) were eligible APCSP entry if they had 1) ≥ two blood relatives (at least one first-degree association); 2) clinical genetic diagnosis...

10.1186/s13053-021-00190-1 article EN cc-by Hereditary Cancer in Clinical Practice 2021-08-16

COVID-19 has led to unprecedented challenges and requires local global efforts for its mitigation. Poor marginalized populations are more vulnerable the health, social economic effects of pandemic. The objective this study was know about knowledge, attitude practices towards among poor communities in central India factors associated with them so that effective risk communication messages can be designed community engagement needs strategies identified. A cross-sectional survey conducted...

10.1371/journal.pone.0264639 article EN cc-by PLoS ONE 2022-04-06

1521 Background: It has previously been reported that 6-7% of clear cell (CC) and endometrioid (E) ovarian cancers are MMR deficient (MMRd). The prevalence MMRd in other histological subtypes correlation with germline (g) (Lynch Syndrome) mutations unselected non-serous EOC pts is less clear. solid tumors associated enhanced response to immunotherapy, hence knowledge status therapeutic familial implications. We aimed study the implications gMMRd EOC. Methods: Routine immunohistochemistry...

10.1200/jco.2019.37.15_suppl.1521 article EN Journal of Clinical Oncology 2019-05-20

10.5694/mja12.10731 article The Medical Journal of Australia 2013-02-01

among men, and from 0.09 to 5.99 percent women.In some countries (Denmark, Switzerland, women in Eastern European countries) the increase is leveling off. ConclusionsThe impact of obesity on life expectancy increasing over time Europe, especially men.The off as observed western could potentially point successful anti-obesity public health initiatives.

10.1093/eurpub/ckx187.734 article EN European Journal of Public Health 2017-10-20

Abstract We aimed to determine whether SNP-microarray genomic testing of saliva had a greater diagnostic yield than blood for pathogenic copy number variants (CNVs). selected patients who underwent CMA both and from 23,289 21,857 samples. Our cohort comprised 370 individuals both, 224 with syndromic intellectual disability (ID) 146 isolated ID. Mosaic CNVs or aneuploidy were detected in but not 20/370 (4.4%). All 20 ID, accounting 9.1% the ID sub-cohort. Pathogenic large size (median 46 Mb),...

10.21203/rs.3.rs-2041176/v1 preprint EN cc-by Research Square (Research Square) 2022-09-14
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