- Hypothalamic control of reproductive hormones
- Diet, Metabolism, and Disease
- Neuropeptides and Animal Physiology
- Inflammasome and immune disorders
- Drug Transport and Resistance Mechanisms
- Tryptophan and brain disorders
- Liver Disease Diagnosis and Treatment
- Sperm and Testicular Function
- Heme Oxygenase-1 and Carbon Monoxide
- Antibiotics Pharmacokinetics and Efficacy
- Ovarian function and disorders
- Endoplasmic Reticulum Stress and Disease
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Phytochemicals and Antioxidant Activities
Karadeniz Technical University
2022-2024
Kisspeptin is an important hormone involved in the stimulation of hypothalamo-pituitary gonadal (HPG) axis. The HPG axis can be suppressed certain conditions such as stress, which gives rise to activation hypothalamo-pituitary-adrenal (HPA) However, physiological role kisspeptin interaction and HPA not fully understood yet. This study was conducted investigate possible effects central injection on well activity. Adult male Wistar rats were randomly divided into seven groups followed: sham...
The purpose of this study was to investigate the effects gentamicin (GEN) on testis and whether quercetin (QUE) has any protective effect.Twenty-four adult male Sprague-Dawley rats were divided into equal four groups: control (0.9% saline solution), GEN (80 mg/kg GEN), QUE (50 QUE) GEN+QUE + 50 QUE).Histopathological (HP) evaluation performed, epididymal sperm parameters analyzed oxidative status evaluated.The use improved HP findings, such as decrease in germinal epithelial thickness...
Aims: Prolonged Endoplasmic Reticulum Stress(ERS) is involved in the pathogenesis of metabolic syndrome, including type-2 diabetes mellitus, cardiovascular diseases, atherosclerosis, obesity, and fatty liver disease. There have been significant efforts to discover molecules treat ERS and/or ameliorate associate symptoms. In this study, we investigated effect 7,8-Dihydroxyflavone(7,8-DHF) on pancreas tissues a cafeteria(CAF) diet induced syndrome model.Main methods: Male C57BL/6 mice were fed...