A5080650765- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Connective tissue disorders research
- Tendon Structure and Treatment
- Spinal Hematomas and Complications
- Medical Imaging and Analysis
National Cheng Kung University Hospital
2022-2025
ABSTRACT Background Previous studies have suggested that changes in the composition of extracellular matrix (ECM) play a significant role development ligamentum flavum hypertrophy (LFH) and histological differences between ventral dorsal layers hypertrophied flavum. Although LFH is associated with increased fibrosis layer, comprehensive research exploring characteristics ECM its mechanical properties both regions limited. Furthermore, distribution fibrosis‐associated myofibroblasts within...
Ligamentum flavum hypertrophy (LFH) is a major cause of lumbar spinal stenosis (LSS). In hypertrophic ligamentum (LF) cells, oxidative stress activates intracellular signaling and induces the expression inflammatory fibrotic markers. This study explored whether healthy LF cells respond differently to stress, via examining levels phosphorylated p38 (p-p38), inducible nitric oxide synthase (iNOS), α-smooth muscle actin (α-SMA). Furthermore, efficacy N-acetylcysteine (NAC), an antioxidant, in...
This video presents a case of L4-5 unstable spondylolisthesis treated with full-endoscopic transforaminal lumbar interbody fusion (Endo-TLIF), emphasizing the GUARD (Glider Used as Rotary Device) technique for nerve root protection. innovative approach involves controlled rotation cage glider before insertion to minimize risk injury, significant complication in Endo-TLIF procedures. The technique, validated previous cadaveric studies, provides enhanced safety during by protecting root. A...
Uniportal full-endoscopic transforaminal lumbar interbody fusion (FE-TLIF) carries a unique risk of nerve traction and abrasion injury during cage insertion. This study aims to evaluate the clinical efficacy GUARD technique delayed ligamentum flavectomy in reducing postoperative radicular pain neurapraxia patients undergoing uniportal FE-TLIF. A retrospective analysis was conducted on 45 with an average age 53.9±12.4 years who underwent either FE facet-sparing TLIF (FE fs-TLIF) or...