A5064377405- Ethnobotanical and Medicinal Plants Studies
- Angiogenesis and VEGF in Cancer
- Natural Antidiabetic Agents Studies
- Plant Toxicity and Pharmacological Properties
- Congenital heart defects research
- Botanical Research and Chemistry
- Cancer, Hypoxia, and Metabolism
- Ubiquitin and proteasome pathways
- Botany, Ecology, and Taxonomy Studies
- Drug-Induced Hepatotoxicity and Protection
- Cancer-related molecular mechanisms research
- Middle East and Rwanda Conflicts
- Consumer Behavior in Brand Consumption and Identification
- Pregnancy and preeclampsia studies
- Indigenous Knowledge Systems and Agriculture
- Phytochemicals and Medicinal Plants
- Regional Socio-Economic Development Trends
- Sugarcane Cultivation and Processing
- Food Science and Nutritional Studies
- Fungal and yeast genetics research
- Cerebrovascular and Carotid Artery Diseases
- Cultural Differences and Values
- Phytochemistry and Biological Activities
- Hibiscus Plant Research Studies
- Cultural Heritage Management and Preservation
University of California, Riverside
2015-2022
Loma Linda University
2010-2013
Walla Walla University
2008
Background: The information of therapeutic medicinal plants used by ethnic/indigenous communities in the south India is constrained at best. These ethnomedicinal treatments constitute a critical local healthcare resource and potential for expanding research on phytomedicines India. present study aims to document evaluate traditional knowledge as well compare distribution examine where efforts are concentrated order gain glimpse current needs future possibilities region.Methods: This...
Background: Local people of the Kumrat Valley, district Upper Dir in Northwest Khyber Pakhtunkhwa, Pakistan rely on wild food plants (WFP) for nutrition, medicine, and monetary value. The present study aimed to accomplish a detailed investigation local their therapeutic importance identify innovative organic products that show potential marketing through use prevalence Methods: Semi-structured interviews group discussion, were conducted from May September 2019. In field survey, 78...
Chronic hypoxia increases vascular endothelial growth factor (VEGF) and thereby promotes angiogenesis. The present study explores the hypothesis that hypoxic in VEGF also remodel artery wall structure contractility through phenotypic transformation of smooth muscle. Pregnant nonpregnant ewes were maintained at sea level (normoxia) or 3,820 m (hypoxia) for final 110 days gestation. Common carotid arteries harvested from term fetal lambs adults denuded endothelium studied vitro....
The present study explores the hypothesis that arterial smooth muscle cells are organized into layers with similar phenotypic characteristics vary relative position between lumen and adventitia due to transmural gradients in vasotrophic factors. A corollary is vascular endothelial growth factor (VEGF) a helps establish variations phenotype. Organ culture of endothelium-denuded ovine carotid arteries 3 ng/ml VEGF-A 165 for 24 h differentially significantly influenced potassium-induced (55%...
Recent studies suggest that vascular endothelial growth factor (VEGF) can modulate smooth muscle phenotype and, consequently, the composition and function of arteries upstream from microcirculation, where angiogenesis occurs. Given hypoxia potently induces VEGF, present study explores hypothesis that, in fetal arteries, VEGF contributes to hypoxic remodeling through changes abundance, organization, contractile proteins. Pregnant ewes were acclimatized at sea level or altitude (3,820 m) for...
This ethnopharmacological investigation aims to collect, identify, and document distinguishable medicinal plant species remedies used by the local people for management of diabetes in Maidan valley district Dir Lower, Khyber Pakhtunkhwa, Pakistan. The have relied on botanical antidiabetic herbal formulations. ethnobotanical interviews, questionnaires, inquiries, group discussions were conducted from March 2019–January 2022 obtain traditional knowledge people. Quantitatively, data analysed...
Aim/Background: Boraginaceae is famous for the production of PAs and some these are carcinogenic, also cause liver failure. So aim present study was to identify presence or absence hepatotoxic pyrrolizidine alkaloids in tribe Lithospermea (Boraginaceae). If any found, it may indicate excluding members this from herbal formulation use on patients with problems. Materials Methods: Plant samples Onosma hispida Wall. ex G. Don, paniculatum Bureau & Franch., hookeri var. longiflorum (Duthie)...
Background: Traditional knowledge and practice prevalence is on an overall decline. In this study, we examine preservation strategies reported in the literature, follow-up measures, categories of traditional conservation practices that are being attempted by non-profit organizations. Methods: To answer these questions, reviewed literature for keywords related to TKP also searched databases organizations with missions preserve such knowledge. We found a range categorized, provide state...
Background: Berberis lycium Royle is a well-known medicinal plant, belonging to the family Berberidaceae, and widely distributed in Lower Dir, Pakistan. Parts of B. like rhizomes berries are used by local people as medicine food.This research work focused on two major aspects regarding lycium. Firstly, determine various traditional uses Secondly, document its monetary value at markets study area.Methods: Semi-structured open-ended ethnobotanical interviews, market inquiries, field...
Histone post‐translational modifications (PTMs) plays a vital role in directing the fate of gene silencing direction either normal cell development and differentiation or aberrant permanent silencing/activation cancer‐related genes. To accurately quantify histone one specific line cancer tissue becomes essential for study epigenetic alteration diseases. Currently, Western‐blot is widely used to assess global while ChIP ChIP‐on‐Chip analysis at location. Mass spectrometry has been recently...
Aim/Background: Trichodesma indicum (L.) Lehm. is a prominent medicinal plant in Pakistan. Various indigenous Pakistani communities use this orally to treat various human ailments. The present study carried out with the aim investigate leaves of T. for presence or absence toxic pyrrolizidine alkaloids (PAs). If these are found, then should be used more precaution. Materials and Methods: For this, dried leaf samples were collected from Northern Pakistan brought Beijing Normal University...
UbpA, a homolog of yeast Ubp14 and human IsoT, is required for multicellular development Dictyostelium . When cells starve, they initiate program whereby aggregate form fruiting bodies. ubpA − are unable to make this growth‐to‐development transition. Starved accumulate ubiquitin‐containing species which may include proteins that must be degraded occur. To identify these proteins, we purified by S5a‐affinity chromatography. MuDPIT mass spec analysis identified 134 more than one peptide 26...