Investigation of the effect nitrogen, boron, sulphur, and phosphor as doping elements on carbon dots, where boron-carbon dots performed good potential for bioimaging application with best optical properties specific targeting features.

Abstract Obesity is associated with a decrease in the levels of sirtuin 1 (SIRT1) and SIRT3 proteins. This reduction can impair activity SIRT1 SIRT3, leading to diminished antioxidant defense, increased oxidative stress, disrupted fatty acid oxidation, reduced energy expenditure. These changes contribute positive balance long-term weight gain. study aims investigate impact moderate-intensity exercise on enhancing obese women. The method used this research true-experimental design involving...

Introduction: Muscle damage can be triggered by other free radicals formed during intense physical activites and the low response of antioxidants. The antioxidants that plays a role in responding to is glutathione peroxidase. Objective: main purpose this study was analyze effects high-intensity moderate-intensity activities on muscle peroxidase (GPx) serum troponin I levels as markers damage. Methodology: used quantitative true experiment with post-test only group design. This conducted at...

Breast cancer is currently one of the most common causes death in women all over world. In breast cancer, proliferation and invasiveness cells are primarily regulated by hormone receptor-mediated signalling, including estrogen, progesterone, human epidermal growth factor receptors. The study aims to conduct an silico investigation using molecular docking dynamic simulation, as well determine cytotoxicity activity selectivity index (SI) 4-methyl-3-benzoyl allylthiourea anti-breast agent....

Insulin resistance is a frequent metabolic disorder in Polycystic Ovary Syndrome (PCOS). Moringa oleifera has been shown to increase insulin expres-sion and decrease the degree of diabetes mellitus, therefore it expected that could levels folliculogenesis PCOS.To prove effect leaf extract various doses might female PCOS-insulin resistant rats.The three month old white rat Wistar strain (Rattus norvegicus) 100-130 grams were divided into five groups (n=8) including normal control,...

Abstract
 Physical activity from many studies has proven to have a positive impact on mental health. But also intense physical over long period, induce athletes feel depressed actually harm Adolescent the load of undergoing special training and competition get high hours competition. Psychological stresses an emotional stress associated with intensive demands, until reduction in athletes' performance abilities skill levels when competing. be one failure reach peak achievement....

This study introduces heteroatom-doped carbon dots (CDs), namely boron-sulphur (BS-CDs) and nitrogen-phosphorus (NP-CDs), highlighting their potential as optical materials for sensitive histamine detection in sensor applications. Synthesized through facile pyrolysis of citric acid cores with non-metal dopants, resulting confirmed graphene-like structures uniform spheres crystal diameters below 3 nm BS-CDs NP-CDs. The properties exhibited blue fluorescence, emission wavelengths 280 (QY 0.08%)...

BACKGROUND: Distinguishing between Acute Coronary Syndrom (ACS) and SCAD (Stable Artery Disease) requires advanced laboratory instrument electrocardiogram. However, their availabilities in primary care settings developing countries are limited. Hematologic changes usually occur the ACS patient might be valuable to distinguish from SCAD.
 AIM: This study compares hematologic indices patients analyses its predictive value for ACS.
 MATERIAL AND METHODS: A total of 191 (79 112 SCAD)...

Objective: This study aimed to look into the therapeutic potential of rutinoside in reducing articular cartilage degeneration a rat model osteoarthritis generated by monosodium iodoacetate (MIA). Methods: We formed three groups male Wistar rats: OA, rutinoside, and control groups. Monosodium (3.0 mg) was injected intra-articularly knee joint cause osteoarthritis. For four weeks, oral administration at 100 mg/kg/day given that were treatment. Histological examination, immunohistochemistry,...

Endometriosis is a gynecological disorder characterized by chronic inflammation, anatomical changes, prolonged pain, and infertility. On the other hand, Phyllanthus niruri recognized for its pharmacological effects, which might be beneficial in managing endometriosis. The aim of study was to investigate effects P. as potential therapy endometriosis using an animal model. An experimental laboratory with randomized, controlled trial, pre-test, post-test design 40 female Wistar rats (Rattus...

Traditional Indonesian fermented foods have been studied as potential probiotics, for example dadiah from West Sumatera are made by fermenting buffalo milk in bamboo tubes. But the of halal probiotics isolated Air Dingin District, Sumatra (Indonesia) has not studied. The purpose this study was to determine probiotic lactic acid bacteria (LAB) Lactobacillus plantarum strain 8m-21 isolation Alahan Panjang Solok Regency against pathogenic and antimicrobial activity. Previously had isolationand...

Background: Extensive wound closure due to trauma, infection and post tumor excision often requires a skin graft procedure. One of the successful factors is good quality recipient tissue vascularization. Reactive oxygen species (ROS) factor that plays role in vascularization, an excessive accumulation ROS can interfere with process Administration antioxidant keep levels from being thus producing vascularization for graft. Propolis has effect antioxidant, inflammation immunomodulator,...

Streptozotocin (STZ)-induced free radical oxidant activity resulted in muscle wasting due to protein carbonyl (PC), glucose transporter-4 (Glut-4), and interleukin-6 (IL-6) alteration. Antioxidant ingredient the golden sea cucumber extract was found promising level inhibit activity.This study aimed investigate effect of on PC, IL-6, Glut-4 STZ-induced diabetes mouse.This performed using mice, which were grouped into non-diabetes, diabetes, diabetes-treated groups. The extracted 70% ethanol,...

This study aimed to analyze the effect of a single bout high-intensity intermittent exercise (HIIE) on serum adiponectin levels in sedentary overweight young adult women. A total 22 obesity women with BMI 23-24.9 m2/kg were enrolled this study. Subjects divided into 2 groups, control and HIIE. The was static cycling for 25 minutes (3 warming up, 20 HIIE, cooling down). HIIE held 10 sets intermittently ratio 1:1, 1 minute 80-90% HRmax, active resting 40 rpm cycling. data taken before hour...

Diabetes dance of Persadia 1 is the evolvement prior diabetes series with aerobic principle and belong to weight bearing exercise eccentric movement. The aim analyze effect on blood level IL-6.16 subjects healthy housewifes who was participated divided 2 groups, group control group. Exercise given 1, 3 times per week, while have unstructured activity. Blood IL-6 has been measured from each subject's that taken after 24 hours post single bout (acute-AE) repeated (chronic exercise-CE). Paired...

AbstrakThe contribution of women to the progress national sports is evidenced through achievement in world-class competitions. Achievements achieved certainly go a training process that not short-lived and health problems often occur as consequence. This study aims describe how much risk occurrence Female Athlete Triad (FAT) Syndrome students. research uses quantitative approach with survey data collection techniques. The respondents were 60 active students from 2014-2019 Faculty Sports...

Background: Pseudomonas aeruginosa is one of the bacteria that cause otitis media, leading to progressive structural damage middle ear mucosa due virulence factor, toxin, and enzyme produced. The excessive inflammatory process can oxidative stress, which will aggravate tissue damage, thus difficult cure. This study aimed assess effect ethanol extract propolis (EEP) in decreasing IL-8 expression blood MDA level media rat model induced by aeruginosa.Methods: A randomized controlled trial was...

This study was purposed to design gossypetin derivatives which have higher activity than the parent compound found in Hibiscus sabdariffa and find most potent as antibacterial agent.Twenty-five were designed by conjugation molecular structure of with acyl group from some natural phenolic acids. The predicted docking simulation on Escherischia coli DNA gyrase (PDB. 1KZN) performed Molegro Virtual Docker. Potency an agent evaluated based binding affinity, hydrogen bond, similarity pattern...

Lupus nefritis (LN) terkait dengan penebalan membran basal glomerulus. Pengendapan kompleks imun memicu kaskade respon inflamasi disertai aktivasi reactive oxygen species (ROS), kemudian menyebabkan fibrosis yang mendorong terjadinya kerusakan ginjal. Interleukin 17 merupakan sitokin sangat berperan pada reaksi tipe-lambat. Produksinya dipicu oleh peningkatan produksi kemokin sejumlah jaringan untuk merekrut monosit dan netrofil ke sisi inflamasi. IL-17 diproduksi sel Th17 diinduksi IL-23....

AbstrakSindroma Ovarium Polikistik (SOPK) merupakan endokrinopati paling umum pada perempuan yang sering dikaitkan dengan resistensi insulin, hyperandrogenemia, peradangan kronis, dan oxydative stress. Tingkat stress SOPK diamati secara signifikan berkorelasi obesitas, bahkan ditemukan memainkan peran penting dalam patogenesis kanker. Antioksidan adalah substansi diperlukan tubuh untuk menetralisir radikal bebas, penggunaan kelor (Moringa Oleifera) sebagai antioksidan perlu diteliti...