Neelu Singh

ORCID: 0000-0001-5830-2018
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Nematode management and characterization studies
  • Nanoparticles: synthesis and applications
  • Nanoplatforms for cancer theranostics
  • Pharmacological Effects of Medicinal Plants
  • Computational Drug Discovery Methods
  • Advanced Drug Delivery Systems
  • Graphene and Nanomaterials Applications
  • Elbow and Forearm Trauma Treatment
  • Advanced biosensing and bioanalysis techniques
  • Electrospun Nanofibers in Biomedical Applications
  • Synthesis and biological activity
  • Bone fractures and treatments
  • Monoclonal and Polyclonal Antibodies Research
  • Orthopedic Surgery and Rehabilitation
  • Phytochemicals and Antioxidant Activities
  • Dermatologic Treatments and Research
  • Biodiesel Production and Applications
  • Wound Healing and Treatments
  • Plant-Derived Bioactive Compounds
  • Ethnobotanical and Medicinal Plants Studies
  • Advancements in Transdermal Drug Delivery
  • Synthesis and Characterization of Heterocyclic Compounds
  • Essential Oils and Antimicrobial Activity
  • Free Radicals and Antioxidants

Babasaheb Bhimrao Ambedkar University
2017-2025

Jawaharlal Nehru University
2019-2024

Indian Council of Forestry Research and Education
2024

Tropical Forest Research Institute
2021-2024

Dr. Hari Singh Gour University
2015-2023

Manipur University
2023

Babasaheb Bhimrao Ambedkar Bihar University
2023

Norwegian Polar Institute
2022

National Institute of Technology Rourkela
2021

Baba Raghav Das Medical College
2020

Several studies have documented that plastic pollution is affecting one of the most remote and pristine regions our planet, Antarctica. Plastics different size polymeric composition been retrieved in Antarctic sea ice, surface waters sediments, with microplastics (mostly fibers) found both terrestrial marine organisms. Such evidence raises concerns about potential detrimental effects on biodiversity ecosystem functions. The present review aims to report up-to-date knowledge occurrence...

10.1016/j.watbs.2022.100034 article EN cc-by Water Biology and Security 2022-03-19

The study was conducted on 20 Holstein X Sahiwal cross bred dairy cows, with an average milk production of 2,752±113.79liters in 284±5.75days during a single lactation, that were divided to two groups 10 animals.We investigated the oxidative stress and antioxidant status transition period cows.In this study, plasma level MDA considered as indicator lipid peroxidation SOD, catalase, GSH GSHPx antioxidants.The significantly (p<0.001) higher cows early lactation compared advanced pregnancy.A...

10.5713/ajas.2011.10220 article EN cc-by Asian-Australasian Journal of Animal Sciences 2011-02-23

Abstract: Infected wounds that do not heal are a worldwide problem is worsening, with more people dying and money being spent on care. For any disease to be managed effectively, its root cause must addressed. Effective wound care becomes bigger when various traditional healing methods products may only fail promote good healing. Still, it also hinder the process, causing stay open longer. Progress in tissue regeneration has led developing three-dimensional scaffolds (3D) or constructs can...

10.2174/1381612829666230816100631 article EN Current Pharmaceutical Design 2023-08-16

The New drugs and Clinical trials rules 2019 (New rules) was introduced on 19th March by Government of India. have set specific requirements for ethics committee (EC). EC is required to follow as per forward their report Central Licensing Authority (CLA). This document divided into different sections like definitions applicable chapter & schedules EC; changes related registration clinical studies biomedical health research; constitution, functions, proceedings, responsibility trial;...

10.4103/picr.picr_208_19 article EN cc-by-nc-sa Perspectives in Clinical Research 2020-01-01

Gout is a painful disorder which does not have an efficient delivery system for its treatment.Development and in vitro, vivo evaluation of allopurinol-loaded nonionic surfactant-based niosomes was envisaged.Niosomes were prepared with Span 20 Tween (1:1 molar ratio) using ether injection method. The formulations screened entrapment efficiency, particle size analysis, zeta potential, release kinetics, activity, stability studies.Stable, spherical vesicles average 304 nm zeta-potential...

10.1080/08982104.2016.1174943 article EN Journal of Liposome Research 2017-01-09

A novel class of phthalimides functionalized with privileged scaffolds was designed, synthesized and evaluated as potential inhibitors plasmepsin 2 (Ki: 0.99 ± 0.1 μM for 6u) 4 3.3 0.3 6t), enzymes found in the digestive vacuole plasmodium parasite considered crucial drug targets. Three compounds were identified candidates further development. The listed also assayed their antimalarial efficacy against chloroquine (CQ) sensitive strain (3D7) Plasmodium falciparum. Assay twenty seven...

10.1371/journal.pone.0139347 article EN cc-by PLoS ONE 2015-10-26

With the advancement of nanotechnology, nano-sized particles make an imprint on our daily lives.The present investigation revealed that biomolecules in seed exudates Vigna radiata are responsible for synthesis AuNPs, confirmed by routine characterization techniques. Anticancer efficacy showed AuNPs might be due to release phytochemicals exudate which is being adsorbed surface referencing their anticancer against tested breast cancer cell lines. Inhibition clonogenicity and cycle arrest at...

10.1016/j.btre.2021.e00612 article EN cc-by-nc-nd Biotechnology Reports 2021-03-27

Designing a metal catalyst that addresses the major issues of solubility, stability, toxicity, cell uptake, and reactivity within complex biological milieu for bioorthogonal controlled transformation reactions is highly formidable challenge. Herein, we report an organoiridium nontoxic capable uncaging allyloxycarbonyl-protected amines under biologically relevant conditions living cells. The potential applications this chemistry have been demonstrated by generation diagnostic therapeutic...

10.1021/acs.inorgchem.1c01790 article EN Inorganic Chemistry 2021-08-15

The current anticancer therapies are limited by their lack of controlled spatiotemporal release at the target site action. We report a novel drug delivery platform that provides on-demand, real-time, organelle-specific and monitoring upon photoactivation. system is comprised model doxorubicin, an alkyltriphenylphosphonium moiety to mitochondria in cancer cells, hydroxycinnamate photoactivatable linker covalently attached mitochondria-targeting moieties such it can be phototriggered either UV...

10.1021/acs.jmedchem.1c00956 article EN Journal of Medicinal Chemistry 2021-12-10

We report a photoactivatable o -hydroxycinnamate–gemcitabine prodrug that shows an efficient drug release with real-time monitoring, and dose- temporally-controlled photocytotoxicity upon visible (one-photon) or NIR (two-photon) light irradiation.

10.1039/d2md00438k article EN RSC Medicinal Chemistry 2023-01-01

The present study is aimed at formulating Genipin crossed curcumin loaded sericin NPs (Cur-SNPs) for the biomedical application in terms of anti-inflammatory and antioxidant potential. Cur-SNPs were prepared by employing modified desolvation method crosslinking using genipin (Gn) optimization particle size, drug entrapment loading. optimized (Opt-Cur-SNPs) exhibited size (263±3.5 nm), efficiency (85.7 ± 1.20%), loading (47.0 1.23%) zeta potential (-25.65 mV). in-vitro release data revealed...

10.1016/j.fhfh.2021.100029 article EN cc-by-nc-nd Food Hydrocolloids for Health 2021-01-01
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