A5086963365- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Adolescent and Pediatric Healthcare
- Intimate Partner and Family Violence
- Family Support in Illness
- Maternal Mental Health During Pregnancy and Postpartum
- Statistical Methods and Inference
- Reproductive System and Pregnancy
- Statistical Methods and Bayesian Inference
- Child Abuse and Trauma
- Endometriosis Research and Treatment
- Posttraumatic Stress Disorder Research
- Marine animal studies overview
- Adolescent Sexual and Reproductive Health
- Wildlife Ecology and Conservation
- Uterine Myomas and Treatments
- Health disparities and outcomes
- Healthcare professionals’ stress and burnout
- Insurance, Mortality, Demography, Risk Management
- Cerebral Palsy and Movement Disorders
- Statistical Methods in Clinical Trials
- Spinal Cord Injury Research
- Economic and Environmental Valuation
- Resilience and Mental Health
- Food Security and Health in Diverse Populations
University of Guelph
2012-2021
University of Michigan
2000-2009
National Institute of Population and Social Security Research
2006-2009
Statistics Canada
2005
Ann Arbor Center for Independent Living
2003
Newcastle University
1999
West Cumberland Hospital
1976-1977
Bipolar disorder is highly heritable and therefore longitudinal observation of children affected parents important to mapping the early natural history.To model developmental trajectory bipolar based on latest findings from an ongoing prospective study offspring with well-characterised disorder.A total 229 families in which 1 parent had confirmed 86 control were prospectively studied for up 16 years. High-risk divided into subgroups parental long-term response lithium. Offspring clinically...
The present study examines the early development of marriage for a representative sample urban white couples and black couples. We are interested in predicting stability these marriages over first 14 years marriage. First, we assess whether objective social economic conditions account divorce time. These factors focus on oppressive conditions, lower status positions society, challenges parenthood family responsibilities. Next, concentrate perceived interactive processes between spouses that...
Although there is growing interest in mental health problems university students limited understanding of the scope need and determinants to inform intervention efforts.To longitudinally examine extent persistence symptoms importance psychosocial lifestyle factors for student academic outcomes.Undergraduates at a Canadian were invited complete electronic surveys entry completion their first year. The baseline survey measured important distal proximal risk follow-up assessed well-being....
As part of the World Health Organization's cross-national research effort, we investigated relationship between various health indicators and experience intimate partner violence (IPV), which included emotional, physical, sexual abuse, among women in Yokohama, Japan.We used multivariate logistic negative binomial regression to examine status IPV a stratified cluster sample 1371 aged 18 49 years.In 9 11 examined, odds experiencing health-related problems were significantly higher (P < .05)...
The purpose of this prospective study was to investigate the effects Boot Camp Survival Training for Navy Recruits—A Prescription (BOOT STRAP) intervention on stress, depression, situational events, interpersonal factors, and recruit training performance. Divisions recruits were randomly selected 801 participated 9 weeks their training. Recruits "at risk" depression assigned or nonintervention groups, remaining served as comparison group. at-risk who received BOOT STRAP significantly...
Summary Biochemical and cytogenetic experiments have led to the hypothesis that eukaryotic chromatin is organized into a series of distinct domains are functionally independent. Two expectations this are: (i) adjacent genes more frequently co‐expressed than expected by chance; (ii) neighbouring often related. Here we report over 10% Arabidopsis thaliana within large, chromosomal regions. per cent (497/22 520) highly ( r > 0.7), about five times number chance. These fall 226 groups...
Abstract Aim Exposure to parental bipolar disorder ( BD ) early in life may increase the risk of developing a mood disorder. However, impact parent–child relationships when parent is affected and how this impacts an offspring's remains unclear. The primary objective study was determine association between offspring parents with and, secondly, interaction temperament stress on association. Methods Two hundred thirty‐three completed annual clinical assessments following K iddie S chedule for A...
Atrial fibrillation (AF) shortens the atrial effective refractory period (ERP) and predisposes to further episodes of AF. The acute changes in refractoriness may be related tachycardia-induced intracellular calcium overload. purpose this study was determine whether digoxin, which increases calcium, potentiates effects AF on humans.In 38 healthy adults, ERP measured at basic drive cycle lengths (BDCLs) 350 500 ms after autonomic blockade. Nineteen patients had been treated with digoxin for 2...
Abstract Title. Creating case scenarios or vignettes using factorial study design methods. Aim. This paper is a report of conducted to develop clinical an adaptation incomplete methodology. Background. In health care, cases are core problem‐based learning, common in practice guideline development processes, and increasingly being used patient care‐giver studies chronic life‐threatening illnesses. A large number behavioural, psycho‐social factors can be relevant such decision problems....
Bipolar disorder is a highly heritable illness that onsets in adolescence and young adulthood. We examined gene expression (mRNA) protein levels of candidate immune neurotrophic markers well-characterized offspring bipolar parents order to identify reliable indicators risk status the early clinical stages development. measured mRNA (TNF-α, IL-1β, IL-10, IFN-δ) (brain-derived factor (BDNF)) from plasma. High-risk were identified families which one parent had confirmed disorder. Control...
Introduction Over 30% of Canadians between the ages 16 and 24 years attend university. This period life coincides with onset common mental illnesses. Yet, data to inform university-based health prevention early intervention initiatives are limited. The U-Flourish longitudinal study based out Queen’s University, Canada involving Oxford University in UK, is a student informed funded by Canadian Institute for Health Research Strategy Patient Oriented (CIHR-SPOR). primary goal research examine...
Objective: To assess associations between female and male factors the risk of recurring Candida vulvovaginitis. Methods: A prospective cohort study 148 women with vulvovaginitis 78 their sexual partners was conducted at two primary care practices in Ann Arbor, Michigan, area. Results: Thirty-three developed least one further episode albicans within 1 year follow-up. Cultures species from various sites woman (tongue, feces, vulva, vagina) her partner urine, semen) did not predict recurrences....
Most studies of physical activity predictors in people with disability have lacked a guiding theoretical framework. Identifying theory-based is important for developing activity-enhancing strategies.To use the World Health Organization's International Classification Functioning, Disability and (ICF) framework to identify leisure time among spinal cord injury (SCI).Six hundred ninety-five persons SCI (M age=47; 76% male) completed measures Body Functions Structures, Activities Participation,...
Bipolar disorder is highly heritable and typically onsets in late adolescence or early adulthood. Evidence suggests that immune activation may be a mediating pathway between genetic predisposition onset of mood disorders. Building on prior study mRNA protein levels high-risk offspring published this Journal, we conducted preliminary examination methylation profiles candidate genes from subsample well-characterized emergent adult (mean 20 years) bipolar parents the Canadian Flourish cohort....
The purpose of this survey was to learn the situation obtaining in several states relative certification requirements for school psychologists. An inspection returns from 42 state departments education shows that only 7 certify (PsycINFO Database Record (c) 2012 APA, all rights reserved)
Attentional ability in 19 survivors of acute lymphoblastic leukaemia and sibling controls was assessed using a neuropsychological model attention. Analysis revealed that children who had received treatment for exhibited significantly poorer performance on measures the "focus encode" execute" elements attention to respond external cues feedback. No significant differences were found sustained shift These results indicate have may experience highly specific attentional deficits could an impact...
During the secretory phase of menstrual cycle, a natural killer (NK) cell subset expressing cluster differentiation (CD)56bright appears in decidualizing uterus and remains until onset menses. If pregnancy occurs, decidual NK cells increase to become predominant uterine lymphocytes early pregnancy. To elucidate mechanisms CD56bright recruitment uterus, an vitro adhesion assay was used assess effect as well cycle-associated hormones on adhesive properties human lymphocytes. Adhesion...
Abstract Background Gastrointestinal illness is an important global public health issue, even in developed countries, where the morbidity and economic impact are significant. Our objective was to evaluate demographic determinants of acute gastrointestinal Canadians. Methods We used data from two population-based studies conducted select communities between 2001 2003. Together, comprised 8,108 randomly selected respondents; proxies were for all respondents under 12 years 19 at discretion...
We consider the problem of predicting achievement successful pregnancy, in a population women undergoing treatment for infertility, based on longitudinal measurements adhesiveness certain blood lymphocytes. A goal analysis is to provide, each woman, an estimated probability becoming pregnant. discuss various existing approaches, including multiple t-tests, mixed models, discriminant and two-stage models. use joint model developed by Wange et al. (2000), consisting linear effects data...