A5014416157- Cardiac electrophysiology and arrhythmias
- S100 Proteins and Annexins
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Receptor Mechanisms and Signaling
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac Arrhythmias and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Cardiomyopathy and Myosin Studies
- Axon Guidance and Neuronal Signaling
- Acute Ischemic Stroke Management
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Signaling Pathways in Disease
- Heart Failure Treatment and Management
Hôpital Louis Pradel
2023-2025
Université Claude Bernard Lyon 1
2024-2025
Hospices Civils de Lyon
2022-2025
Laboratoire CarMeN
2024
Abstract Ventricular fibrillation (VF)-induced cardiac arrest frequently complicates ST-segment elevation myocardial infarction (STEMI). Although larger infarct sizes (IS) correlate with a higher risk of VF, the influence VF itself on IS has remained poorly investigated. To address this knowledge gap, we analyzed effect in patients and two experimental models. From prospective cohort, 30 STEMI were matched 1:2 without common determinants IS. The primary endpoint was IS, assessed using 48-h...
Background Cardiac adrenergic receptor gene polymorphisms have the potential to influence risk of developing ventricular fibrillation (VF) during ST-segment-elevation myocardial infarction, but no previous study has comprehensively investigated those most likely alter norepinephrine release, signal transduction, or biased signaling. Methods and Results In a case-control study, we recruited 953 patients with infarction without cardiac history, 477 primary VF, 476 controls genotyped them for...
Introduction: Despite progress in the field, risk stratification for sudden death patients with hypertrophic cardiomyopathy (HCM) remains challenging. Although ventricular arrhythmias (VA) account most of these events, mechanisms responsible cardiac arrest HCM are not understood. Hypothesis: Abnormalities myocardial perfusion may create an arrhythmogenic substrate patients. Methods/ Results: A 12-year-old boy was admitted to our department after out-of-hospital arrest, documented...