A5020916008- Environmental Toxicology and Ecotoxicology
- Pharmaceutical and Antibiotic Environmental Impacts
- Aquaculture disease management and microbiota
- Seaweed-derived Bioactive Compounds
- Aquaculture Nutrition and Growth
- Algal biology and biofuel production
- Marine Bivalve and Aquaculture Studies
- Nanoparticles: synthesis and applications
- Identification and Quantification in Food
- Marine Sponges and Natural Products
- Selenium in Biological Systems
- Vibrio bacteria research studies
- Biosensors and Analytical Detection
- Medical and Biological Ozone Research
- Pesticide and Herbicide Environmental Studies
- Animal testing and alternatives
- Dental materials and restorations
- Marine Biology and Environmental Chemistry
- Pharmacological Effects and Toxicity Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Meat and Animal Product Quality
- Echinoderm biology and ecology
- Insect and Pesticide Research
- Effects and risks of endocrine disrupting chemicals
- Chemistry and Chemical Engineering
Rudjer Boskovic Institute
2016-2025
University of Zagreb
1993-2014
University of Split
2008
Ericaria crinita and amentacea from the Adriatic Sea (Croatia) were investigated with respect to presence of less-polar compounds for first time after fractionation by solid-phase extraction (SPE). The composition fractions freeze-dried E. (FdEc) (FdEa) analyzed high-performance liquid chromatography–high-resolution mass spectrometry electrospray ionization (UHPLC-ESI-HRMS). major identified were: amides higher aliphatic acids (palmitoleamide, linoleamide, palmitamide, oleamide erucamide)...
Soft 3-amidoquinuclidine quaternary ammonium compounds (QACs) with dual antibacterial mode of action and reduced toxicity.
The endemic brown macroalga Fucus virsoides J. Agardh from the Adriatic Sea was in focus of present research. volatiles fresh (FrFv) and air-dried (DrFv) samples F. obtained by headspace solid-phase microextraction (HS-SPME) hydrodistillation (HD) were analyzed gas chromatography equipped with flame ionization detector mass spectrometry (GC-FID/MS). major HS-FrFv compound pentadecane (61.90–71.55%) followed pentadec-1-ene (11.00–7.98%). In HS-DrFv, not present, few lower aliphatic compounds...
The marine environment has a significant impact on life Earth. Organisms residing in it are vital for the ecosystem but also serve as an inexhaustible source of biologically active compounds. Herein, biodiversity two brown seaweeds, Dictyota dichotoma and fasciola from Adriatic Sea, was evaluated. aim study determination differences compound composition while comparing their activities, including antioxidant, antimicrobial, enzyme inhibition, connection to human digestion, dermatology,...
Abstract Amazonian wildfires in 2019 have raised awareness about rainforest burning due to increased emissions of particulate matter and carbon. In the context these emissions, by-products lignin thermal degradation (i.e. methoxyphenols) are often neglected. Methoxyphenols entering atmosphere may form intermediates with currently unknown reaction mechanisms toxicity. This study for first time provides a comprehensive insight into impact products [guaiacol, catechol], their nitrated...
Due to the lack of phytochemical composition data, major goals present study on Amphiroa rigida J.V. Lamouroux were to: (a) investigate and compare volatilome profiles fresh air-dried samples obtained by headspace solid-phase microextraction (HS-SPME) hydrodistillation (HD) followed gas chromatography mass spectrometry (GC/MS) analysis; (b) determine fatty acids profile with flame ionization detector (GC-FID); (c) obtain pigment semipurified extracts high performance liquid (HPLC) (d)...
Codium adhaerens from the Adriatic Sea (Croatia) was comprehensively investigated regarding less polar compounds for first time. Although there are several phytochemical studies on C. other regions, this is report volatile organic (VOCs) fresh (FrCa) and air-dried (DrCa) samples. The novelty also related to its targeted antioxidant potential in vitro vivo. main aims were to: (a) identify compare VOCs of FrCa DrCa obtained by headspace solid-phase microextraction (HS-SPME) hydrodistillation...
Multixenobiotic resistance (MXR) is an important mechanism of cellular efflux mediated by ATP binding cassette (ABC) transporters that bind and actively remove toxic substrates from the cell. This study was first to identify ABC transporter P-glycoprotein (P-gp/ABCB1) as a representative MXR phenotype in earthworm (Eisenia fetida). The identified partial cDNA sequence ABCB1 overlapped with homologues other organisms 58.5 % 72.5 %. We also studied effect five modulators (verapamil,...
Vibrio (Listonella) anguillarum is a pathogenic bacterium causing septicaemia in wide range of marine organisms and inducing severe mortalities, thus it crucial to conduct its accurate rapid identification. The aim this study was assess MALDI-TOF MS as method choice for identification clinical V. isolates from affected fish. Since the accuracy might be influenced by type medium used, well incubation conditions, we tested grown on standard media with without addition NaCl, cultured at three...
MALDI-TOF MS was tested for the identification of Photobacterium damselae subsp. piscicida on isolates grown two media, cultured at three incubation times and applied target plate by direct sample spotting (DS), on-target extraction (OTE) full (FE) method, in triplicates. The samples blood agar (BA) outperformed tryptic soya (TSA) 0.64% DS OTE. OTE gave highest scores both culture all replicates. Reliable 24-hr species 61.54%, 84.61% 53.85% TSA identified DS, FE, respectively. For BA, they...
The total synthesis of two new marine natural products, (±)-marinoaziridine B 7 and (±)-N-methyl marinoaziridine A 8, was accomplished. prepared in a six-step linear sequence with 2% overall yield. key steps our strategy were the preparation chiral epoxide (±)-5 using Johnson Corey Chaykovsky reaction, followed by ring-opening reaction Staudinger reaction. N,N-dimethylation compound (±)-7 gives 8. NMR spectra synthetized isolated product did not match. compounds are biologically...
The present work is the first study of Mediterranean scallop (Pecten jacobaeus) biochemical properties, antioxidant defenses, and free radical scavengers during yearly seasons in Northern Adriatic, off Istria. Scallop nutrient reserves (glucose, triglyceride, cholesterol) four tissues under examination were positively correlated predominant digestive gland gonad. muscle energy maxima correlation with maximum fall gonosomatic index (GSI), when diatoms coccolithophorids thrive. decrease GSI...