- Multiple Myeloma Research and Treatments
- Health Literacy and Information Accessibility
- Mobile Health and mHealth Applications
- Social Media in Health Education
- Health and Medical Research Impacts
- Protein Degradation and Inhibitors
- Glycosylation and Glycoproteins Research
- Biomedical Ethics and Regulation
- Chronic Lymphocytic Leukemia Research
- Biomedical and Engineering Education
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Peripheral Artery Disease Management
- CAR-T cell therapy research
- Clostridium difficile and Clostridium perfringens research
- Chronic Disease Management Strategies
- Palliative Care and End-of-Life Issues
- Innovations in Medical Education
- Health Sciences Research and Education
- Diversity and Career in Medicine
- Peptidase Inhibition and Analysis
- Liver Disease Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Genomic variations and chromosomal abnormalities
- Sex and Gender in Healthcare
- Technology Use by Older Adults
Boston Scientific (United States)
2023-2024
Mayo Clinic
2013-2022
Mayo Clinic in Florida
2012-2022
Mayo Clinic in Arizona
2012-2022
Ocean Medical Center
2022
University Medical Center
2022
Hackensack Meridian Health
2022
WinnMed
2012-2021
National Cancer Institute
2016-2021
University of Mississippi Medical Center
2021
Objective: During the past decade, availability of health information online has increased dramatically. We assessed progress toward Healthy People 2020 (HP2020) communication and technology objective increasing proportion seekers who easily access online. Methods: used data from 4 administrations Health Information National Trends Survey (HINTS 2008-2017) (N = 18 103). conducted multivariable logistic regression analysis to evaluate trends over time in experiences with accessing examine...
Abstract Purpose The increase in use of health information technologies (HIT) presents new opportunities for patient engagement and self‐management. Patients rural areas stand to benefit especially from increased access care tools electronic communication with providers. We assessed the adoption 4 HIT over time by or urban residency. Methods Analyses were conducted using data 7 iterations National Cancer Institute's Health Information Trends Survey (HINTS; 2003‐2014). Rural/urban residency...
As the year 2020 approaches, there is a need to evaluate progress toward United States government's Healthy People (HP2020) health information technology and communication objectives establish baselines upon which 2030 can be based.The aim of this study was use National Cancer Institute's (NCI) Health Information Trends Survey (HINTS) benchmark HP2020 goals related increasing internet access using broadband, assess state digital divide for various sociodemographic groups.We merged analyzed...
Public understanding of the role genetics in disease risk is key to appropriate prevention and detection. This study assessed current extent awareness use genetic testing US population. Additionally, identified characteristics subgroups more likely be at for low literacy.The used data from National Cancer Institute's 2017 Health Information Trends Survey, including measures awareness, applications usage. Multivariable logistic regression models estimated associations between...
To determine the prognosis of patients with non-secretory myeloma.We studied 124 diagnosed multiple myeloma who had no monoclonal protein detected on serum and urine immunofixation at diagnosis all subsequent follow-up testing (non-secretory myeloma). The overall survival (OS) was compared 6953 typical seen during same time period in whom a diagnosis.One hundred twenty-four met criteria for myeloma. median 102 months (range, 1-204 months). progression-free initial therapy 28.6 months, OS...
In the United States, national incentives for offering access to electronic personal health records (ePHRs) through means are geared toward creating a culture of patient engagement. One group patients who stand benefit from online ePHRs is growing population with multiple chronic conditions (MCC). However, little known about current availability and use portals among those managing MCC.The aim was determine associations between number sociodemographic characteristics usage ePHRs, assess how...
Objectives. To examine prevalence and predictors of digital health engagement among the US population. Methods. We analyzed nationally representative cross-sectional data on 7 behaviors, as well demographic socioeconomic predictors, from Health Information National Trends Survey (HINTS 5, cycle 2, collected in 2018; n = 2698-3504). fitted multivariable logistic regression models using weighted survey responses to generate population estimates. Results. Digitally seeking information (70.14%)...
We examined four clinically assessed cytogenetic subtypes (t(11;14), t(4;14), monosomy 13/del13q and 17/del17p in 292 black patients with newly diagnosed multiple myeloma (MM) from medical centers, who had fluorescent situ hybridization testing results available their records. then compared the prevalence of these abnormalities a previously characterized Mayo Clinic cohort 471 MM. found significant difference t(11;14) immunoglobulin heavy chain (IgH) translocation between blacks whites, 6.5%...
Artificial intelligence (AI) is the most recent development in a long series of disruptive technological innovations radiology. Medical imaging began late 1800s after discovery X-ray, but exploded 1900s with availability computers to create, analyze, and store digital images. Future speculation about radiology includes widespread AI involvement; however, thus far, translation clinical has been limited. The historical context for artificial applications falls at intersection radiographic...
Abstract Translational stories range from straightforward to complex. In this commentary, the story of rapid and successful translation rituximab therapy for treatment non‐Hodgkin's lymphoma (NHL) is examined. Development monoclonal antibody began in late 1980s. 1994, received its first approval NHL by United States Food Drug Administration (FDA). Rituximab has since been approved additional indications transformed medical practice. However, social political implications these successes are...
The contemporary healthcare system can help improve health literacy outcomes in two ways: first, by nurturing the skills and motivations needed for patients to be actively engaged their own decisions; and, second, creating a prepared proactive that adapts patients' capacities needs efficacious ways. In 2001, National Cancer Institute launched Health Information Trends Survey (HINTS) as way researchers planners understand how public is interacting with rapidly changing information...
Healthy People 2020 (HP2020) aims to improve population health outcomes through several objectives, including communication and information technology. We used 7 administrations of the Health Information National Trends Survey examine HP2020 goals toward access Internet broadband mobile devices (N = 34 080). conducted descriptive analyses obtained predicted marginals, also known as model-adjusted risks, estimate association between demographic characteristics use devices. The target (7.7% US...
Objectives/Hypothesis: To investigate the relationship between expression of FOXM1, CEP55, and HELLS in oropharyngeal squamous cell carcinoma to human papillomavirus (HPV), smoking, tumor stage. Study Design: Retrospective cohort study. Methods: Transcriptome data were analyzed from matched tumor-normal samples taken patients with carcinoma. Data previously generated using deep-sequencing techniques (mRNA-Seq). Transcript levels all three genes validated NanoString nCounter system a larger...
The introduction of novel immunomodulatory drugs (IMiDs) has dramatically improved the survival patients with multiple myeloma (MM). While it been shown that specific cytogenetic subtypes, namely t(4;14), have best outcomes when treated bortezomib-based regimens, relationship between subtypes and response to IMiDs remains unclear. Using DNA synthesis assays, we investigated subtype lenalidomide in a representative panel human cell lines (HMCLs). We examined HMCL protein expression levels...