A5085574396- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Wound Healing and Treatments
- Facial Rejuvenation and Surgery Techniques
- Body Image and Dysmorphia Studies
- Digital Imaging in Medicine
- Botulinum Toxin and Related Neurological Disorders
- Reconstructive Facial Surgery Techniques
- Mesenchymal stem cell research
- Dermatologic Treatments and Research
- Body Contouring and Surgery
- Breast Cancer Treatment Studies
- Social Media in Health Education
- Nerve injury and regeneration
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Anatomy and Medical Technology
- Pressure Ulcer Prevention and Management
- 3D Printing in Biomedical Research
- Orthopedic Surgery and Rehabilitation
- Biomedical Ethics and Regulation
- Diversity and Career in Medicine
- Tissue Engineering and Regenerative Medicine
- COVID-19 and healthcare impacts
- Hair Growth and Disorders
University College London
2016-2025
Royal Free London NHS Foundation Trust
2015-2025
The Royal Free Hospital
2016-2025
Nottingham University Hospitals NHS Trust
2025
Queen's Medical Centre
2025
National Health Service
2025
Manipal University College Malaysia
2025
Royal London Hospital
2016-2024
British Association of Plastic, Reconstructive and Aesthetic Surgeons
2023-2024
Roland Hill (United Kingdom)
2002-2024
Abstract Development of biosynthetic conduits carrying extracellular matrix molecules and cell lines expressing neurotrophic growth factors represents a novel promising strategy for spinal cord peripheral nerve repair. In the present in vitro study, compatibility growth‐promoting effects (i) alginate hydrogel, (ii) hydrogel complemented with fibronectin, (iii) matrigel were compared between olfactory ensheathing cells (OECs), Schwann (SCs), bone marrow stromal (BMSCs). Neurite outgrowth from...
Schwann cell (SC) transplantation has been proposed to encourage peripheral nerve regeneration, but an optimal SC-carrying matrix would be needed. The aim of this study was characterize how the addition fibronectin alginate affect outcome regeneration promoted by cells embedded in matrix. Genetically labeled rat SCs were obtained lacZ gene transduction. suspended hydrogel with/without liquid fibronectin, and their viability growth different types matrices assessed vitro AlamarBlue assay. In...
In Brief Summary: Autologous nerve grafts are the current criterion standard for repair of peripheral injuries when transected ends not amenable to primary end-to-end tensionless neurorrhaphy. However, donor-site morbidities such as neuroma formation and permanent loss function have led tremendous interest in developing an alternative this technique. Artificial conduits therefore emerged autologous grafting short defects less than 30 mm; however, they do yet surpass clinically. A thorough...
This study aimed to assess the burden and economic impact of disease associated with plastic reconstructive surgery in United Kingdom. We calculated a value per statistical life year £60,000 person Kingdom ($75,510 U.S. dollars). found that 2019, estimated age-standardized incident rates, death disability-adjusted years surgery-related conditions were 361.47 100,000, 19.5 100,000 551.0 respectively. Burn emerged as leading contributor overall burden, accounting for 32%, followed by decubitus...
Abstract Transplantation of Schwann cells (SCs) is a promising treatment modality to improve neuronal regeneration. Identification the transplanted an important step when studying development this method. Genetic labeling most stable and reliable method cell identification, but it still unclear whether has deleterious effect on SC characteristics. Our aim was achieve population SCs transduced with lacZ gene at high frequency using retroviral vector in vitro, follow labeled vitro assess their...
Augmented reality (AR) is defined as "a technology that superimposes a computer-generated image on user's view of the real world, thus providing composite view."1 This case report describes how emerging AR telesurgery technologies may be used to facilitate international surgeon-surgeon collaboration and training. Here, we illustrate remote surgeon in Beirut, Lebanon, was able offer assistance Gaza, Palestine, during complex hand reconstruction following bomb-blast injury an 18-year-old male....
The use of bioresorbable conduits supplemented with Schwann cells (SCs) is a promising tissue engineering technique to replace nerve grafting. Alginate hydrogel (AH), as SC matrix, has many advantages over previously used matrices but not been evaluated for this purpose. In study, the viability and proliferation SCs together function in AH was vitro. AlamarBlue™ cell assay monitor compared collagen gel, fibrin glue, hyaluronic acid, Matrigel®, standard culture plate 5 days culture. results...
Abstract Chronic, nonhealing diabetic foot ulcers (DFU) are increasing in prevalence and often unresponsive to conventional therapy. Adipose tissue, containing adipose‐derived stem cells, platelet rich plasma (PRP) regenerative therapies growth factors which may provide a solution chronic wound healing. This study aimed assess the feasibility of conducting definitive randomised controlled trial (RCT) investigate efficacy these for treatment DFU. was single centre, feasibility, three‐arm,...
Hand microsurgery is an important advancement of the speciality that has improved outcomes in hand trauma and surgical conditions. This bibliometric analysis aims to identify 75 most cited articles explore their relevance contemporary practice. The Web Science core collection database was used screen top most-cited relevant microsurgery. VOSviewer 1.6.18 CiteSpace 6.2.R4 software were analyse visualise occurrences, authorship, countries, institutions, journals, keywords, Evidence Level...
Abstract Background Botulinum toxin is widely used in aesthetic medicine, with numerous studies examining its efficacy and safety. Objectives This bibliometric analysis aims to describe research trends assess the methodological quality of highest-impact botulinum applications. Methods The authors this study identified 100 most-cited publications on aesthetics using Web Science, covering all available journal years (from inception October 2024). Oxford Centre for Evidence-Based Medicine Level...