Debajit Thakur

ORCID: 0000-0001-5942-4818
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About
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Research Areas
  • Microbial Natural Products and Biosynthesis
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Genomics and Phylogenetic Studies
  • Fungal Biology and Applications
  • Cancer-related molecular mechanisms research
  • Mycorrhizal Fungi and Plant Interactions
  • Advanced biosensing and bioanalysis techniques
  • Nanoparticles: synthesis and applications
  • Carbon and Quantum Dots Applications
  • Microbial Metabolism and Applications
  • Plant Pathogens and Resistance
  • Antibiotic Resistance in Bacteria
  • Plant Disease Resistance and Genetics
  • Actinomycetales infections and treatment
  • Bacteriophages and microbial interactions
  • Quantum Dots Synthesis And Properties
  • Nematode management and characterization studies
  • Electrochemical sensors and biosensors
  • Plant tissue culture and regeneration
  • Biosensors and Analytical Detection
  • Nanocluster Synthesis and Applications
  • Antimicrobial Resistance in Staphylococcus
  • Legume Nitrogen Fixing Symbiosis
  • Salivary Gland Disorders and Functions

Institute of Advanced Study in Science and Technology
2016-2025

Academy of Scientific and Innovative Research
2025

Gauhati University
2025

Dr. Yashwant Singh Parmar University of Horticulture and Forestry
2024

Ministry of Science and Technology
2022

Cotton University
2020

Asian Institute of Technology
2015

Indian Institute of Technology Guwahati
2014

Tea Research Association
2009-2011

North East Institute of Science and Technology
2004-2009

Plant growth promoting rhizobacteria (PGPR) are studied in different agricultural crops but the interaction of PGPR tea crop is not yet well. In present study, indigenous were isolated from seven estates Darjeeling located West Bengal, India. A total 150 rhizobacterial isolates screened for antagonistic activity against six fungal pathogens i.e. Nigrospora sphaerica (KJ767520), Pestalotiopsis theae (ITCC 6599), Curvularia eragostidis 6429), Glomerella cingulata (MTCC 2033), Rhizoctonia...

10.1371/journal.pone.0182302 article EN cc-by PLoS ONE 2017-08-03

A mesophilic actinomycete strain designated as PB-52 was isolated from soil samples of Pobitora Wildlife Sanctuary Assam, India. Based on phenotypic and molecular characteristics, the identified Nocardia sp. which shares 99.7% sequence similarity with niigatensis IFM 0330 (NR_112195). The is a Gram-positive filamentous bacterium rugose spore surface exhibited wide range antimicrobial activity against bacteria including methicillin resistant Staphylococcus aureus (MRSA), Gram-negative yeasts....

10.3389/fmicb.2016.00347 article EN cc-by Frontiers in Microbiology 2016-03-18

Actinobacteria are often known to be great producers of antibiotics. The rapid increase in the global burden antibiotic-resistance with concurrent decline discovery new antimicrobial molecules necessitates search for novel and effective metabolites from unexplored ecological niches. present study investigated producing actinobacterial strains isolated soils two microbiologically forest ecosystems, viz. Nameri National Park (NNP) Panidehing Wildlife Sanctuary (PWS), located Eastern Himalayan...

10.1186/s12866-018-1215-7 article EN cc-by BMC Microbiology 2018-07-11

Abstract Actinobacteria is a goldmine for the discovery of abundant secondary metabolites with diverse biological activities. This study explores antimicrobial biosynthetic potential and diversity actinobacteria from Pobitora Wildlife Sanctuary Kaziranga National Park Assam, India, lying in Indo-Burma mega-biodiversity hotspot. A total 107 were isolated, which 77 exhibited significant antagonistic activity. 24 isolates tested positive at least one polyketide synthase type I, II or...

10.1038/s41598-020-60968-6 article EN cc-by Scientific Reports 2020-03-05

Plant associated endophytic actinobacteria may contribute to plant growth and defense by direct or indirect methods. Our aim was evaluate the promoting antifungal activities of with Camellia spp. related genera, Eurya find potent strains that could be applied in future microbe based bioformulations. We isolated 46 on morphological characteristics isolates. 16S rRNA gene sequence analysis showed represented nine actinobacterial Nocardia, Amycolatopsis, Streptomyces, Pseudonocardia, Kribbella,...

10.3389/fmicb.2020.00318 article EN cc-by Frontiers in Microbiology 2020-02-28

In the present study, 217 rhizobacterial isolates were obtained from six different tea estates of Assam, India and subjected to preliminary in vitro plant growth promotion (PGP) screening for indole acetic acid (IAA) production, phosphate solubilization, siderophore production ammonia production. Fifty showed all PGP traits five did not exhibit any traits. These 50 potential further analyzed quantitative estimation along with aminocyclopropane-1-carboxylate (ACC) deaminase, protease...

10.3389/fmicb.2015.01252 article EN cc-by Frontiers in Microbiology 2015-11-10

Tea (Camellia sinensis (L.) O. Kuntze) is an economically important caffeine‐containing beverage crop with massive plantation in the Northeast corner of agroclimatic belt India. The main aim work was to isolate, identify and characterize native plant growth promoting endophytes associated tea for future microbe based bioformulation. A total 129 endophytic bacteria were isolated characterized traits such as indole‐3‐acetic acid (IAA), phosphate solubilization, ammonia production, biocontrol...

10.1111/jam.14356 article EN Journal of Applied Microbiology 2019-06-19

Endophytes are well-acknowledged inoculants to promote plant growth, and extensive research has been done in different plants. However, there is a lacuna about the endophytes associated with tea clones their benefit growth. The present study focuses on isolating characterizing beneficial endophytic bacteria (EnB) prevalent commercially important cultivated North Eastern India as growth promoters. Diversity of culturable EnB microbiome, vitro traits for promotion (PGP), applicability potent...

10.3389/fmicb.2021.738058 article EN cc-by Frontiers in Microbiology 2021-09-30

In this work, we report a smart stimuli-responsive drug delivery system (DDS) that can release depending upon the amount of pathogen (MRSA) present in target. A greater MRSA will lead to more and vice versa. Carbon-dot-coated novel alginate beads (CA-CD) exhibiting superior stability was successfully used as vehicle. Garlic extract (GE), which contains allicin, taken model demonstrate phenomena. It observed GE loading 19 78% with CA CA-CD, respectively. CA-CD-GE shows pH-dependent controlled...

10.1021/acsami.6b10914 article EN ACS Applied Materials & Interfaces 2016-12-01

Mutagenic and Carcinogenic substances are a threat to any living organism, its detection is of paramount importance. In this work, we fabricate for the first time DNA-carbon dots based electrochemical biosensor sensitive selective mutagenic nitrosamines like N-nitrosodimethylamine (NDMA) N-nitrosodiethanolamine (NDEA). At first, on glassy carbon electrode (GCE), chitosan dot was deposited, then, DNA electro-statically immobilizing surface sensing (DNA/chiCD/GCE modified electrode). presence...

10.1021/acsabm.0c00073 article EN ACS Applied Bio Materials 2020-02-17

A biopolymer-based formulation for robust and active food packaging material was developed. This consisted of a blend three biopolymers (guar gum–sodium alginate–i-carrageenan) reinforced by cellulose nanocrystals (CNC) alongside the integration silver nanoparticles (AgNPs) with varying sizes. The CNC utilized in this process derived from cloth waste lint (CWL) generated household dryer machine. synthesis underwent series solvent treatments to yield used composite. AgNPs were incorporated...

10.1021/acs.biomac.3c01076 article EN Biomacromolecules 2024-02-20

Introduction. Cold atmospheric plasma (CAP) has emerged as a promising technology for neutralizing microbes, including multidrug-resistant strains. This study investigates CAP's potential an alternative to traditional antimicrobial drugs microbial inactivation.Hypothesis/Gap Statement. In the era of increasing resistance, there is persistent need strategies. CAP exerts its effects by generating reactive oxygen and nitrogen species (RONS), but comparative efficacy against requires further...

10.1099/jmm.0.001965 article EN Journal of Medical Microbiology 2025-01-29

Hypertension, a significant global health issue, is particularly prevalent in low- and middle-income countries, such as India, where it affects approximately 25-30% of the population. The rising incidence hypertension largely attributed to urbanization, lifestyle changes, an aging demographic. Among various antihypertensive treatments, diuretics, especially thiazide remain cornerstone management due their proven efficacy, cost-effectiveness, accessibility. Clinical practice guidelines from...

10.35629/4494-100211381149 article EN 2025-02-01
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