A5033080256- Escherichia coli research studies
- Hepatitis B Virus Studies
- Urinary Tract Infections Management
- Antibiotic Resistance in Bacteria
- Hepatitis C virus research
- Dermatological and COVID-19 studies
- CRISPR and Genetic Engineering
- SARS-CoV-2 and COVID-19 Research
- HIV Research and Treatment
- COVID-19 Clinical Research Studies
- Bacteriophages and microbial interactions
Tanta University
2019-2024
University of Missouri
2019
Abstract Background Uropathogenic Escherichia coli (UPEC) is the main etiological agent behind community-acquired and hospital-acquired urinary tract infections (UTIs), which are among most prevalent human infections. The management of UPEC becoming increasingly difficult owing to multi-drug resistance, biofilm formation, possession an extensive virulence arsenal. This study aims characterize isolates in Tanta, Egypt, with regard their antimicrobial phylogenetic profile, virulence, as well...
Moloney leukemia virus 10 (MOV10) is an RNA helicase that has been shown to affect the replication of several viruses. The effect MOV10 on Hepatitis B (HBV) infection not known and its role this poorly understood. We investigated down-regulation over-expression HBV in a variety cell lines, as well system using competent virus. report down-regulation, siRNA, shRNA, CRISPR/Cas9 gene editing technology, resulted increased levels DNA, pre-genomic RNA, core protein. In contrast, reduced These...
COVID-19 is an infectious disease caused by SARS-CoV-2 and has spread globally, resulting in the ongoing coronavirus pandemic. The current study aimed to analyze clinical epidemiological features of Egypt. Oropharyngeal swabs were collected from 197 suspected patients who admitted Army Hospital confirmation positivity was performed rRT-PCR assay. Whole genomic sequencing conducted using Illumina iSeq 100® System. average age participants 48 years, which 132 (67%) male. main symptoms...
Uropathogenic Escherichia coli (UPEC) is the primary etiologic agent of urinary tract infections (UTIs). This study aimed to investigate difference in antimicrobial susceptibility UPEC isolates planktonic and biofilm states. Important virulence factors were also evaluated. The minimum inhibitory concentrations (MICs) determined recorded as 0.5-64 μg/ ml for amikacin, cefotaxime, 0.25-64 cefepime, 0.25-16 meropenem, 0.125-32 ciprofloxacin. Biofilm-specific resistance was assessed using...