Xudong Wen

ORCID: 0000-0001-5969-1326
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About
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Research Areas
  • Gallbladder and Bile Duct Disorders
  • Pancreatic and Hepatic Oncology Research
  • Pediatric Hepatobiliary Diseases and Treatments
  • High Altitude and Hypoxia
  • RNA modifications and cancer
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pancreatitis Pathology and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Medicinal Plants and Bioactive Compounds
  • Cancer-related molecular mechanisms research
  • Biliary and Gastrointestinal Fistulas
  • Electromagnetic wave absorption materials
  • Liver physiology and pathology
  • Cancer, Stress, Anesthesia, and Immune Response
  • Astrophysical Phenomena and Observations
  • Pulsars and Gravitational Waves Research
  • Vagus Nerve Stimulation Research
  • Tissue Engineering and Regenerative Medicine
  • Supercapacitor Materials and Fabrication
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease Diagnosis and Treatment
  • Monetary Policy and Economic Impact
  • Tryptophan and brain disorders
  • Advanced Sensor and Energy Harvesting Materials
  • Retinal Diseases and Treatments

Chengdu University of Traditional Chinese Medicine
2022-2024

First Affiliated Hospital of Chengdu Medical College
2020-2024

Chengdu University
2024

Huaqiao University
2024

Southwest Jiaotong University
2022-2024

Nanjing Forestry University
2024

Beijing Normal University
2023

Integrated Chinese Medicine (China)
2023

Army Medical University
2016-2022

Chengdu Women's and Children's Central Hospital
2022

Abstract With the development of modern medicine, importance continuous and reliable pulse wave monitoring has increased significantly in physiological evaluation disease diagnosis. Among them, 3D reconstruction is indispensable, needs rely on ultra‐high resolution sensor arrays, that is, high spatial resolution, temporal force resolution. Herein, a flexible high‐density 32 × tactile array based pressure‐sensitive tunneling mechanism develpoed. Conformal graphene nanowalls ( GNWs ) pattern...

10.1002/adfm.202406022 article EN Advanced Functional Materials 2024-06-10

AIM:To investigate the efficacy and safety of adjuvant sorafenib after curative resection for patients with Barcelona Clinic Liver Cancer (BCLC)-stage C hepatocellular carcinoma (HCC).METHODS: Thirty-four HCC patients, classified as BCLC-stage C, received highrisk tumor recurrence hepatectomy at a tertiary care university hospital.The study group was compared case-matched control 68 who during period in 1:2 ratio. RESULTS:The rate markedly lower (15/34, 44.1%) than (51/68, 75%, P =...

10.3748/wjg.v22.i23.5384 article EN cc-by-nc World Journal of Gastroenterology 2016-01-01

Homeobox B7 (HOXB7) has been identified associated with poor prognosis of hepatocellular carcinoma (HCC). However, the specific mechanism by which HOXB7 promotes malignant progression HCC remains to be determined.Immunohistochemistry (IHC) was used detect expression level in 77-paired tissue samples, and correlation between assessed. The location confirmed immunofluorescence. Cell Titer-Blue assay assess proliferation hepatoma cells. stem-like properties cells were analysed sphere formation...

10.1186/s13046-017-0559-4 article EN cc-by Journal of Experimental & Clinical Cancer Research 2017-06-24

Diabetic cardiomyopathy (DCM) is one of the most common complications diabetes without effective treatment options. Its pathogenesis complex and remains unclear. Long non-coding RNA (lncRNA) MIAT allele has been reported to be enriched in DCM patients activate a pyroptosis program hypoxia-induced H9c2 cells. Thus, whether played role clarified. In study, expression was found elevated serum diabetic patients, as well high-glucose induced cardiomyocytes mice. Further, levels CASP1 correlation...

10.1016/j.isci.2021.103518 article EN cc-by-nc-nd iScience 2021-11-26

Hepatocellular carcinoma is associated with high mortality, and tumor metastasis an important reason for poor prognosis. However, has not been effectively prevented in clinical therapy the mechanisms underlying have fully characterized. CCAAT/enhancer-binding protein-α (C/EBPα) a transcriptional regulator essential role metastasis. We used short-activating RNAs (saRNA) to enhance expression of C/EBPα. Intravenous injection C/EBPα-saRNA nude mouse liver orthotopic xenograft model inhibited...

10.1371/journal.pone.0153117 article EN cc-by PLoS ONE 2016-04-06

Colorectal cancer (CRC) is the third most diagnosed worldwide. Progesterone associated with a decreased risk of CRC and leads to favourable prognosis. However, specific mechanism by which progesterone suppresses malignant progression remains be elucidated. In present study, level was first analysed in 77 patients CRC, immunohistochemistry performed detect expression receptor (PGR) paired specimens. The correlations between progesterone, PGR prognosis were assessed. A Cell Counting Kit‑8...

10.3892/or.2021.8046 article EN cc-by-nc-nd Oncology Reports 2021-04-09

The promotion of liver regeneration is crucial to avoid failure after hepatectomy. Angelica sinensis polysaccharide (ASP) and Astragalus membranaceus (AMP) have been identified as being associated with hepatoprotective effects. However, their roles specific mechanisms in remain be elucidated. In the present study, it suggested that respective use ASP or AMP strikingly promoted hepatocyte proliferation vitro a wide range concentrations (from 12.5 μg/mL 3200 μg/mL), stronger promoting effect...

10.3390/molecules27227890 article EN cc-by Molecules 2022-11-15

Individual tree canopy extraction plays an important role in downstream studies such as plant phenotyping, panoptic segmentation and growth monitoring. Canopy volume calculation is essential part of these studies. However, existing methods based on LiDAR or UAV-RGB imagery cannot balance accuracy real-time performance. Thus, we propose a two-step individual volumetric modeling method: first, use RGB remote sensing images to obtain the crown information, then spatially aligned point cloud...

10.3390/f15081375 article EN Forests 2024-08-06

Phyllanthus emblica Linn. fruit that primarily contains many polyphenols, have been considered homologous food for centuries and used as a remedy variety of ailments, including maintaining brain function. It is, however, unclear what is the mechanism protective action polyphenols (PEFPs) against cognitive impairment anxiety induced by acute paradoxical sleep deprivation (SD). Behavioral abnormalities SD were effectively alleviated PEFPs, which also prevented histopathological morphological...

10.1016/j.jff.2023.105884 article EN cc-by Journal of Functional Foods 2023-11-01

Diabetic cardiomyopathy (DCM), a common complication of diabetes, is defined as ventricular dysfunction in the absence underlying heart disease. Noncoding RNAs (ncRNAs), including long noncoding (lncRNAs) and microRNAs (miRNAs), play crucial role development DCM. Weighted Gene Co-Expression Network Analysis (WGCNA) was used to identify key modules DCM-related pathways. miRNA-mRNA network ceRNA were constructed by miRNA-seq hub genes these modules. We identified five that are associated with...

10.1038/s41598-023-37378-5 article EN cc-by Scientific Reports 2023-06-24

Purpose: High-altitude environment mainly with hypobaric hypoxia could induce pathological alterations in ocular tissue. Previous studies have mostly focused on sporadic case reports and simulated high-altitude experiments. This aim of this study was to explore the proteomic morphological changes tissue mice at real altitude environment. Methods: In study, were flown from Chengdu (elevation: 500 m) Lhasa 3600 m). After exposure for 1day, 3, 6, 10, 20, 30, 40days, euthanatized obtain blood...

10.2147/jir.s361174 article EN cc-by-nc Journal of Inflammation Research 2022-05-01
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