Cinthia D. Ortega

ORCID: 0000-0001-6013-8982
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Surgical Treatments
  • Colorectal and Anal Carcinomas
  • Radiomics and Machine Learning in Medical Imaging
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Treatments and Studies
  • Cervical Cancer and HPV Research
  • Medical Imaging Techniques and Applications
  • Pelvic floor disorders treatments
  • Pancreatic and Hepatic Oncology Research
  • Platelet Disorders and Treatments
  • Parasites and Host Interactions
  • Parasitic infections in humans and animals
  • Gynecological conditions and treatments
  • Genetic factors in colorectal cancer
  • Cancer Immunotherapy and Biomarkers
  • Gastric Cancer Management and Outcomes
  • Blood Coagulation and Thrombosis Mechanisms
  • Aortic aneurysm repair treatments
  • Parasitic Infections and Diagnostics
  • MRI in cancer diagnosis
  • Diagnosis and treatment of tuberculosis
  • Cardiac, Anesthesia and Surgical Outcomes
  • Intramuscular injections and effects
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Foreign Body Medical Cases

Universidade de São Paulo
2010-2025

Hospital Israelita Albert Einstein
2024

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2012-2024

Instituto do Câncer do Estado de São Paulo
2015-2024

Bellvitge University Hospital
2021

Institut d'Investigació Biomédica de Bellvitge
2021

Institute of Rural Management Anand
2017

Hospital Sírio-Libanês
2016

Hemochromatosis can be classified as (a) primary, when it originates from a genetic disturbance that promotes the increase of iron absorption, or (b) secondary, relates to chronic diseases multiple transfusions. The distribution accumulation differs between these two forms; therefore, they distinguished by using imaging methods in majority cases. Magnetic resonance (MR) is most sensitive and specific modality diagnosis hemochromatosis. susceptibility effect caused leads signal loss affected...

10.1148/rg.296095511 article EN Radiographics 2009-10-01

BACKGROUND: Selected patients with rectal cancer and complete clinical response after neoadjuvant chemoradiation have been managed nonoperatively acceptable outcomes. However, ≈20% of these will develop early tumor regrowth. Identification could select candidates for more intensive follow-up. OBJECTIVE: The purpose this study was to investigate the influence baseline radiological T classification on recurrences a chemoradiation. DESIGN: This retrospective review prospective collected...

10.1097/dcr.0000000000000830 article EN Diseases of the Colon & Rectum 2017-05-06

BACKGROUND: A variety of definitions for a clinical near-complete response after neoadjuvant (chemo) radiotherapy rectal cancer are currently used. This leads to inconsistency in practice, long-term outcome, and trial enrollment. OBJECTIVE: The aim this study was reach expert-based consensus on the definition radiotherapy. DESIGN: modified Delphi process, including systematic review, 3 surveys, 2 meetings, performed with an international expert panel consisting 7 surgeons 4 radiologists....

10.1097/dcr.0000000000003209 article ES Diseases of the Colon & Rectum 2024-05-02

Several pancreatic diseases may require surgical treatment, with most of these procedures classified as resection or drainage. Resection procedures, which are usually performed to remove tumors, include pancreatoduodenectomy, central pancreatectomy, distal and total pancreatectomy. Drainage treat chronic pancreatitis after the failure medical therapy Puestow Frey procedures. The type surgery depends not only on patient's symptoms location disease, but also expertise surgeon. Radiologists...

10.1148/rg.323105121 article EN Radiographics 2012-05-01

The observation of inferior oncologic outcomes after surgery for proximal colon cancers has led to the investigation alternative treatment strategies, including surgical procedures and neoadjuvant systemic chemotherapy in selected patients.The purpose this study was determine accuracy CT staging cancer detecting unfavorable pathologic features that may aid selection ideal candidates extended lymph node dissection and/or chemotherapy.This a retrospective consecutive series.Trained abdominal...

10.1097/dcr.0000000000001387 article EN Diseases of the Colon & Rectum 2019-03-19

BACKGROUND: Select patients with complete clinical response to chemoradiation have been managed without radical surgery. The presence of radiologic evidence nodal metastases at baseline could be a risk factor for local tumor regrowth, more advanced stage the time recurrence, and worse distant metastases-free survival. OBJECTIVE: purpose this study was compare outcomes node-positive node-negative cancer after neoadjuvant nonoperatively. DESIGN: This retrospective review consecutive...

10.1097/dcr.0000000000001337 article EN Diseases of the Colon & Rectum 2019-03-19

Abstract Background Neoadjuvant chemoradiation(nCRT) has been considered the preferred initial treatment strategy for distal rectal cancer. Advantages of this approach include improved local control after radical surgery but also opportunity organ preserving strategies (Watch and Wait-WW). Consolidation chemotherapy(cCT) regimens using fluoropyrimidine-based with or without oxalipatin following nCRT have demonstrated to increase complete response preservation rates among these patients....

10.1186/s12885-023-10984-2 article EN cc-by BMC Cancer 2023-06-14

Magnetic resonance imaging is a method with high contrast resolution widely used in the assessment of pelvic gynecological diseases. However, potential such to diagnose vaginal lesions still underestimated, probably due scarce literature approaching theme, poor familiarity radiologists diseases, some them relatively rare, and many peculiarities involved vagina. Thus, authors illustrate role magnetic evaluation diseases main relevant findings be considered clinical decision making process. A...

10.1590/0100-3984.2013.1726 article EN Radiologia Brasileira 2015-08-01

Developments in the multidisciplinary treatment of rectal cancer with advances preoperative magnetic resonance imaging (MRI), surgical techniques, neoadjuvant chemoradiotherapy, and adjuvant chemotherapy have had a significant impact on patient outcomes, increasing rates curative surgeries reducing pelvic recurrence. Patients recurrence worse prognoses, an morbidity mortality. Although local is more frequent within 2 years resection primary tumor, late may occur. Clinical manifestations can...

10.1186/s13244-024-01842-1 article EN cc-by Insights into Imaging 2024-11-11

Liver surgery may be a curative treatment option not only for primary liver neoplasms but also metastases in selected patients. The number of surgeries performed worldwide has increased, surgical morbidity associated with these remains significant. Therefore, radiologists need to understand the terminology, techniques, resectability and unresectability criteria, possible postoperative complications as are part decision-making process. Because vascular biliary variations common, an adequate...

10.1148/rg.210124 article EN Radiographics 2022-04-01

Abstract Aim Full‐thickness local excision after neoadjuvant chemoradiotherapy ( CRT ) for patients with rectal cancer and incomplete clinical response has been a treatment strategy organ preservation. Follow‐up of these is challenging since anatomic distortion postoperative changes may be clinically indistinguishable from tumour recurrence. MRI have role in detecting The aim this study was to describe the findings during follow‐up having following without Method data were collected...

10.1111/codi.13691 article EN Colorectal Disease 2017-04-24

e15503 Background: SCCAC is a rare disease. The standard of care treatment with curative intent chemoradiation (CRT) mitomycin (MMC) or cisplatin (CDDP) plus infusional 5-Fluoracil (5-FU). Capecitabine may replace 5-FU in MMC doublet. However, and pumps are frequently unavailable underdeveloped countries. CCDP capecitabine widely available, but there no prospective data about the feasibility efficacy this combination definitive CRT setting. Methods: A Prospective cohort study aimed to...

10.1200/jco.2024.42.16_suppl.e15503 article EN Journal of Clinical Oncology 2024-06-01

OBJECTIVE. The purpose of this study was to evaluate CT as a screening tool for determining high risk local recurrence rectal tumors in scenario limited MRI availability. MATERIALS AND METHODS. Data were retrospectively analyzed 180 consecutively registered patients with adenocarcinoma and no previous treatment who underwent baseline staging within 30 days each other. Two radiologists independently reviewed MR images. scans interpreted multiplanar reformation. High based on the reference...

10.2214/ajr.18.20929 article EN American Journal of Roentgenology 2019-04-17

3141 Background: Cervical and anal canal squamous cell carcinoma (SSC) are a significant health problem in underdevelopment countries. Definitive chemoradiation (CRT) is the standard-of-care (SOC) approach for curative treatment locally advanced disease. Due to common substantial local inflammation during CRT, conventional clinical image cannot identify non-responders early. In this scenario, evaluation of circulating tumor DNA (ctDNA) promising tool real-time response monitoring. Methods:...

10.1200/jco.2024.42.16_suppl.3141 article EN Journal of Clinical Oncology 2024-06-01

<title>Abstract</title> Background Localized Squamous Cell Anal Cancer (SCCAC) is a rare disease. The standard of care treatment with curative intent chemoradiation (CRT) mitomycin (MMC) or cisplatin (CDDP) plus infusional 5-Fluoracil (5-FU). Capecitabine may replace 5-FU in MMC doublet. However, and pumps are frequently unavailable underdeveloped countries. CCDP capecitabine widely available, but there no prospective data about the feasibility efficacy this combination definitive SCCAC CRT...

10.21203/rs.3.rs-4964999/v1 preprint EN 2024-10-17

Aims & Objectives: Patients with liver dysfunction are prone to metabolic complications of citrate accumulation when submitted continuous veno-venous hemodiafiltration (CVVHDF) regional anticoagulation (RCA). Methods: From May 2019 December 2022, 109/1970 (5.5%) patients admitted PICU were CVVHDF-RCA, where 53/109 (48.6%) had dysfunction. Data related minimum magnesemia was analyzed sensitize the results. Results: Clinical characteristics: age = 2.9 years (IQR:1-12.8); weight 12Kg (IQR:...

10.1097/01.pcc.0001086052.67088.1b article EN Pediatric Critical Care Medicine 2024-11-01
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