Steven D. Wexner

ORCID: 0000-0001-8046-5753
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Surgical Treatments
  • Anorectal Disease Treatments and Outcomes
  • Diverticular Disease and Complications
  • Pelvic floor disorders treatments
  • Colorectal Cancer Screening and Detection
  • Colorectal and Anal Carcinomas
  • Gastric Cancer Management and Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Inflammatory Bowel Disease
  • Hernia repair and management
  • Stoma care and complications
  • Microscopic Colitis
  • Genetic factors in colorectal cancer
  • Congenital gastrointestinal and neural anomalies
  • Gastrointestinal motility and disorders
  • Colorectal Cancer Treatments and Studies
  • Enhanced Recovery After Surgery
  • Appendicitis Diagnosis and Management
  • Intestinal and Peritoneal Adhesions
  • Gastrointestinal disorders and treatments
  • Diversity and Career in Medicine
  • Surgical Simulation and Training
  • Esophageal and GI Pathology
  • Minimally Invasive Surgical Techniques
  • Abdominal Surgery and Complications

Cleveland Clinic Florida
2016-2025

Health Affairs
2021-2025

Délégation Paris 6
2020-2024

Twitter (United States)
2022-2024

Kuwait Petroleum Corporation (Kuwait)
2023-2024

Hochschule Düsseldorf University of Applied Sciences
2020-2024

The Bronx Defenders
2024

Color (United States)
2024

Cleveland Clinic
2008-2023

Mount Sinai Hospital
2023

This goal of this research was to develop and evaluate the psychometrics a health-related quality life scale developed address issues related specifically fecal incontinence, Fecal Incontinence Quality Life Scale.The Scale is composed total 29 items; these items form four scales: Lifestyle (10 items), Coping/Behavior (9 Depression/Self-Perception (7 Embarrassment (3 items).Psychometric evaluation scales demonstrates that they are both reliable valid. Each demonstrate stability over time...

10.1007/bf02237236 article EN Diseases of the Colon & Rectum 2000-01-01

Constipation is a common complaint; however, clinical presentation varies with each individual. The aim of this study was to assess standard scoring system for evaluation constipated patients.All consecutive patients idiopathic constipation who were referred anorectal physiologic testing assessed. A subjective score calculated based on detailed questionnaire that included over 100 constipation-related symptoms. Based the questionnaire, scores ranged from 0 30, indicating normal and 30 severe...

10.1007/bf02056950 article EN Diseases of the Colon & Rectum 1996-06-01

IMPORTANCEEvidence about the efficacy of laparoscopic resection rectal cancer is incomplete, particularly for patients with more advanced-stage disease.OBJECTIVE To determine whether noninferior to open resection, as determined by gross pathologic and histologic evaluation resected proctectomy specimen.DESIGN, SETTING, AND PARTICIPANTS A multicenter, balanced, noninferiority, randomized trial enrolled between October 2008 September 2013.The was conducted credentialed surgeons from 35...

10.1001/jama.2015.10529 article EN JAMA 2015-10-06

The purpose of this research was to develop and evaluate a severity rating score for fecal incontinence, the Fecal Incontinence Severity Index.The Index is based on type x frequency matrix. matrix includes four types leakage commonly found in incontinent population: gas, mucus, liquid solid stool five frequencies: one three times per month, once week, twice day, day. developed using both colon rectal surgeons patient input specification weighting scores.Surgeons patients had very similar...

10.1007/bf02236199 article EN Diseases of the Colon & Rectum 1999-12-01

To assess readiness of general surgery graduate trainees entering accredited surgical subspecialty fellowships in North America.A multidomain, global assessment survey designed by the Fellowship Council research committee was electronically sent to all program directors. Respondents spanned minimally invasive surgery, bariatric, colorectal, hepatobiliary, and thoracic specialties. There were 46 quantitative questions distributed across 5 domains 1 or more reflective qualitative...

10.1097/sla.0b013e3182a191ca article EN Annals of Surgery 2013-08-09

BACKGROUND: Our primary objective was to demonstrate the utility and feasibility of intraoperative assessment colon rectal perfusion using fluorescence angiography (FA) during left-sided colectomy anterior resection. Anastomotic leak (AL) after colorectal resection increases morbidity, mortality, and, in cancer cases, recurrence rates. Inadequate may contribute AL. The PINPOINT Endoscopic Fluorescence Imaging System allows for anastomotic perfusion. STUDY DESIGN: This is a prospective,...

10.1016/j.jamcollsurg.2014.09.015 article EN cc-by-nc-sa Journal of the American College of Surgeons 2014-09-28

It should be recognized that these guidelines not deemed inclusive of all proper methods care or exclusive reasonably directed to obtaining the same results. The ultimate judgment regarding propriety any specific procedure must made by physician in light circumstances presented individual patient.

10.1007/bf02258291 article EN Diseases of the Colon & Rectum 2000-03-01

Although Seprafilm has been demonstrated to reduce adhesion formation, it is not known whether its usage would translate into a reduction in adhesive small-bowel obstruction.This was prospective, randomized, multicenter, multinational, single-blind, controlled study. This report focuses on those patients who underwent intestinal resection (n = 1,701). Before closure of the abdomen, were randomized receive or no treatment. applied adhesiogenic tissues throughout abdomen. The incidence and...

10.1007/s10350-005-0268-5 article EN Diseases of the Colon & Rectum 2005-11-30

A multicenter retrospective study was undertaken to assess the efficacy and safety of laparoscopy in colon rectal surgery. To minimize potential bias interpretation results, all data were registered with an independent observer, who did not participate any surgical procedures. Sixty-six patients underwent a laparoscopic procedure. Operations performed included sigmoid colectomy (19), right hemicolectomy (15), low anterior resection (6), ileal pouch-anal anastomosis (IPAA) (5),...

10.1007/bf02050298 article EN Diseases of the Colon & Rectum 1993-01-01

To determine the disease-free survival (DFS) and recurrence after treatment of patients with rectal cancer open (OPEN) or laparoscopic (LAP) resection.This randomized clinical trial (ACOSOG [Alliance] Z6051), performed between 2008 2013, compared LAP OPEN resection stage II/III cancer, within 12 cm anal verge (T1-3, N0-2, M0) in who received neoadjuvant chemoradiotherapy. The rectum mesorectum were resected using instruments for dissection (included hybrid hand-assisted laparoscopic) under...

10.1097/sla.0000000000003002 article EN Annals of Surgery 2018-08-03

Sacral nerve stimulation has been approved for use in treating urinary incontinence the United States since 1997, and Europe both fecal (FI) 1994. The purpose of this study was to determine safety efficacy sacral a large population under rigors Food Drug Administration-approved investigational protocol.Candidates SNS who provided informed consent were enrolled Institutional Review Board-approved multicentered prospective trial. Patients showing > or =50% improvement during test received...

10.1097/sla.0b013e3181cf8ed0 article EN Annals of Surgery 2010-02-19

Limited data have been published regarding the long-term results of sacral nerve stimulation, or neuromodulation, for severe fecal incontinence.The aim was to assess outcome stimulation with use precise tools and collection, focusing on durability therapy. Five-year were analyzed.Patients entered in a multicenter, prospective study incontinence followed at 3, 6, 12 months annually after device implantation.Patients chronic whom conservative treatments had failed who not candidates more...

10.1097/dcr.0b013e318276b24c article EN Diseases of the Colon & Rectum 2013-01-09

Abstract Background Complex perianal fistulas are a serious complication in patients with Crohn’s disease (CD). Darvadstrocel (DVS), suspension of expanded adult allogeneic adipose-derived mesenchymal stem cells, is approved Europe and Japan for treatment complex (CPF). The global ADMIRE-CD II phase 3 randomized double-blind placebo-controlled study evaluated the efficacy safety DVS CPF. Methods Patients aged 18–75 years clinically controlled, inactive or mildly active CD CPF (≤2 internal...

10.1093/ecco-jcc/jjad212.0018 article EN Journal of Crohn s and Colitis 2024-01-01

PURPOSE: This study was undertaken to determine the early experience of embers COST Study Group with colorectal cancer treated by laparoscopic approaches. METHOD: A retrospective review performed all patients laparoscopy before August 1994. Tumor site, stage, differentiation, procedure completion, presence recurrence (local, distant, trocar site), and cause death were analyzed. RESULTS: total 372 adenocarcinoma colon rectum approach between October 1991 1994 (170 men 192 women): right...

10.1007/bf02053806 article EN Diseases of the Colon & Rectum 1996-10-01

PURPOSE: The management of complex perianal fistulas with endorectal advancement flap is aimed at avoiding the risk sphincter injury associated traditional surgical methods. Long-term follow-up required to assess recurrence and continence outcomes this procedure. aim study was review our experience in treatment define predictors successful healing. METHODS: A retrospective chart all patients who underwent for between 1988 2000 performed. Follow-up established by telephone interview. RESULTS:...

10.1007/s10350-004-7248-z article EN Diseases of the Colon & Rectum 2002-12-01
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