A5026024865- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Wound Healing and Treatments
- Hernia repair and management
- Biliary and Gastrointestinal Fistulas
- Surgical site infection prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Surgical Treatments
- Intestinal and Peritoneal Adhesions
- Reconstructive Surgery and Microvascular Techniques
- Pelvic and Acetabular Injuries
- Appendicitis Diagnosis and Management
- Body Contouring and Surgery
- Pancreatic and Hepatic Oncology Research
- Inflammatory Bowel Disease
- Pancreatitis Pathology and Treatment
- Pressure Ulcer Prevention and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Surgical Sutures and Adhesives
- Aortic aneurysm repair treatments
- Diabetic Foot Ulcer Assessment and Management
- Esophageal and GI Pathology
- Foreign Body Medical Cases
- Venous Thromboembolism Diagnosis and Management
- Gastric Cancer Management and Outcomes
Bispebjerg Hospital
2013-2024
Frederiksberg Hospital
2010-2024
Copenhagen University Hospital
2017-2024
Skive Hospital
2024
University of Copenhagen
2012-2023
Capital Region of Denmark
2010-2016
Holbæk Sygehus
2014-2016
Aarhus University Hospital
2011
Wound Healing Society
2001-2006
Papworth Hospital
1997
In Brief Objective Clinical studies show that the incidence of postoperative wound complications is higher in smokers than nonsmokers. this study, we evaluated effect abstinence from smoking on incisional infection. Methods Seventy-eight healthy subjects (48 and 30 never-smokers) were included study followed for 15 weeks. first week smoked 20 cigarettes per day. Subsequently, they randomized to continuous smoking, with transdermal nicotine patch (25 mg day), or placebo patch. At end 4, 8, 12...
Several studies have examined the association between anastomotic leakage and intraoperative risk factors in colorectal surgery, but only a few taken patients' lifestyle into account. The aim of this study was to assess such as smoking habits alcohol consumption.Between January 1993 October 1996, 333 unselected consecutive patients one surgical department underwent colonic or rectal resection with anastomosis. clinical 24 variables related patient history, diagnosis surgery assessed...
<h3>Hypothesis</h3> A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings smoking as a factor wound complications and recurrence groin hernia, we studied whether is associated with hernia. <h3>Design</h3> Cohort study. Clinical follow-up study 33 to 57 months following laparotomy gastrointestinal disease. Variables predictive were assessed by multiple regression analysis. <h3>Setting</h3> Department Surgery,...
Surgical site infections and disruption of sutured tissue are frequent complications following surgery. We aimed to assess risk factors predictive wound in open gastrointestinal surgery.Data from 4855 unselected patients undergoing surgery 1995 through 1998 were recorded a clinical database validated. The embraced variables related patient history, preoperative condition, operative findings severity, the surgeon's training. Variables surgical infection dehiscence within 30 days after...
Smokers have a higher risk of complicated tissue and wound healing after surgery than nonsmokers. We tested the hypothesis that short-term pre-operative cessation smoking in colorectal decreases incidence postoperative complications.From February 1998 to March 2001, 60 patients, who smoked daily, undergoing resection were randomly assigned 2-3 weeks before scheduled either abstinence from smoking, counselling nicotine replacement therapy or maintenance daily habits. Postoperative...
ABSTRACT Delayed wound healing may explain postoperative tissue and dehiscence in smokers, but the effects of smoking cessation on cellular mechanisms remain unclear. Suction blisters were raised 48 smokers 30 never smokers. The fluid was retrieved epidermal roof excised. Transepidermal water loss (TEWL) measured after 2, 4, 7 days. Then, randomized to continuous or abstinence with a transdermal nicotine patch placebo by concealed allocation. sequence repeated 8, 12 weeks all abstainers 6...
Full-thickness 5 mm punch biopsy wounds were made lateral to the sacrum in 48 smokers and 30 never smokers. After 1 week, excised fixed. The then randomized continuous smoking or abstinence with a transdermal nicotine patch placebo patch. sequence of wounding excision was repeated after 4, 8, 12 weeks. All tissue stained hematoxylin-eosin immunohistochemically for macrophages (CD68), procollagen N-terminal propeptide (PINP) fibroblasts, endothelial cells (CD31). cellularity assessed scored...
The objectives for this study were to examine the associations between metabolic biomarkers of obesity including insulin resistance, vascular dysfunction, systemic inflammation, genetic susceptibility and ultrasound proven gallstone disease or cholecystectomy in a population-based cross-sectional study.A total 2650 participants included, whom 422 had disease. Associations selected estimated by multivariable logistic regression models expressed as odds ratio (OR) 95% confidence interval...
Soluble urokinase plasminogen activator receptor (suPAR) is a stable inflammatory biomarker. In patients, suPAR marker of disease presence, severity and prognosis. the general population, predictive development, such as diabetes cardiovascular and, in smokers, long-term lung cancer development. Whether smoking cessation impacts level unknown.Forty-eight smokers were randomized into three groups 16: (i) continued to smoke 20 cigarettes per day, (ii) refrained from used transdermal nicotine...