Adverse childhood experiences (ACEs) have a significant impact on person's psychological development and predispose them to various harmful consequences in adulthood, such as different forms of aggression. Contrarily, positive (PCEs) operate protective factors, buffering against the adverse effects ACEs promoting adaptive behaviors well-being. However, role PCEs relationship between aggression remains relatively unexplored.

Pleasure-seeking reasons are the main drivers of pornography use (PU), but regulation unpleasant states, namely distraction from or suppression negative emotions and stress relief, other potential predictors this behavior.Our objective is to develop an explanatory model problematic PU, assessing difficulties in emotion regulation, loneliness, perceived stress, as well age gender predictors.A cross-sectional study was conducted that included a total 340 participants (M = 28.50 years, SD...

Pancreatic panniculitis is a rare complication of pancreatic disease occurring in 2% to 3% all patients, most commonly those with acute or chronic pancreatitis.We report the case associated pancreatitis 63-year-old man. He presented 2-day history multiple tender subcutaneous nodules, followed by nausea, vomiting, severe epigastric pain and loss appetite, hours before admission. Laboratory radiologic findings revealed pancreatitis. Histopathological examination from skin biopsy specimen taken...

The understanding of how individuals manage their emotional experiences has flourished dramatically over the last decades, including assessing emotion (dys)regulation. Difficulties in Emotion Regulation Scale (DERS) is a well-validated and extensively used self-report instrument for regulation problems. Despite wide use DERS both clinical research settings, its length potentially increases fatigue frustration respondents limits inclusion brief protocols. Consequently, short-form version...

Immune reconstitution inflammatory syndrome (IRIS) is a recently described entity in which severely immunodepressed HIV patients, after being started on HAART, develop reactions to several pathogens. We present patient who developed extensive Molluscum Contagiosum (MC) lesions shortly HAART. With the progression of immunoreconstitution, healed spontaneously. contagiosum are presumably common IRIS but underreported. point out this case for its striking clinical picture and well-documented...

Abstract Background Morphea is a rare chronic inflammatory disease that involves skin and subcutaneous tissues, causing sclerosis. Generalized morphea characterized by extensive cutaneous involvement poor response to therapy. Although the pathophysiology for not completely understood, abnormal signaling through platelet‐derived growth factor transforming beta axes seems play major role in sclerotic process. Imatinib, tyrosine kinase inhibitor, interferes with both pathways. Recent studies...

Patients with HIV infection have a higher propensity for infectious, inflammatory, neoplastic and metabolic disorders. The link psoriasis vulgaris is explained by well-known pathophysiological phenomena can be observed at any stage of infection. aim our study was to characterize the clinical spectrum in group 50 patients HIV. Our findings showed particular presentations those patients, suggesting predilection scalp lesions, palmoplantar keratoderma flexural involvement, as well trend towards...

Methylmethacrylate was first reported in 1941 as a cause of contact dermatitis. Since then, occupational allergies to acrylates dentistry, orthopedic surgery, printing industry and have been reported, but few reports are found the literature consequence with sculptured artificial acrylic nails which increasingly popular. We describe here 3 patients allergy nails. Patch tests were performed Portuguese baseline series allergens an extended applied. In particular, we tested three female...

The main objective of the current study was to analyze mediating role perceived stress on relationship between childhood trauma and sleep disturbances among adult population. sample this cross-sectional composed 987 Portuguese adults with disturbances, who completed a self-administered questionnaire about trauma, stress. results analyses found that in model included variables stress, both were predictors disturbances; however, strongest predictor. Regarding subtypes maltreatment, only...

Laurus nobilis is a common plant in the Mediterranean area, and used several cosmetic products remedies due to its claimed analgesic, antioxidant anti-inflammatory effects (1).Laurel oil contains cineol, pinene, citral, terpineol, sesquiterpene lactones (2).Contact allergy laurel has been mostly

Fungal invasive infections are rare in general population but an emergent cause of infection the immunocompromized population, especially solid organ transplant recipients. Herein authors report a clinical case liver transplanted patient suffering cutaneous co-existent with A. alternata as well infectoria. To our knowledge this is first concomitant due to those two species reported not only Portugal also worldwide. The was treated surgical excision lesions and oral itraconazol without relapse.

Dermatofibromas are common benign skin neoplasms.The authors report the clinical, dermoscopic and histopathological features of a hemosiderotic dermatofibroma mimicking melanoma in an 85-year-old woman.Atypical patterns may prove difficult to differentiate from melanocytic lesions, because its polymorphic, melanoma-like presentation, definite diagnosis can be reached by examination.

Objectives: To analyze the association between difficulties in emotion regulation and problematic pornography use (PPU) test mediating effect of loneliness. Methods: All 339 participants (M = 28.53 years, SD 10.32) completed online self-report scales assessing regulation, PPU, Results: Difficulties are positively correlated with PPU. Loneliness partially mediates relationship Gender intimate status had moderating effects on tested mediation model. Conclusions: Greater have a significant...

Introduction: Several preservatives are currently allowed in cosmetic products the EU. However, only a few of them strongly represented on market: formaldehyde, parabens, formaldehyde releasers and methylchoroisothiazolinone/methylisothiazolinone (MCI/MI). MCI/MI has been widely used during recent years for preservation aqueous systems cosmetics, toiletries several industrial applications.

Granuloma annulare is a granulomatous skin disease of unknown aetiology. It more common in women and has disseminated form 10–15% patients. A small portion these patients have an associated such as diabetes mellitus, viral infection, vaccine reaction or cancer. Haematological neoplasms adenocarcinomas are those most frequently found.1 The authors present the case 68-year-old man with recent diagnosis hepatocellular carcinoma (figure 1). Simultaneously diagnosis, he referred to appearance...

Sex offenders who cross over in victims’ age, gender and relationship usually have a greater number of victims, which is associated with sexual recidivism. This investigation aimed to examine the prevalence crossover index offending Portugal, explore predictive ability sociodemographic criminological variables on this outcome. A retrospective sample 247 male individuals incarcerated for sex offenses Portuguese prison was drawn from official records. From those multiple victims ( n = 94), 48%...