A5101451899- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
- Traumatic Brain Injury Research
- Patient-Provider Communication in Healthcare
- Traumatic Brain Injury and Neurovascular Disturbances
- Intensive Care Unit Cognitive Disorders
- Palliative Care and End-of-Life Issues
- Patient Satisfaction in Healthcare
- Medical and Health Sciences Research
- Empathy and Medical Education
- Clinical practice guidelines implementation
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Simulation-Based Education in Healthcare
- Clinical Reasoning and Diagnostic Skills
- Emergency and Acute Care Studies
- Non-Invasive Vital Sign Monitoring
- Healthcare professionals’ stress and burnout
- Health and Medical Studies
- Healthcare cost, quality, practices
- Long-Term Effects of COVID-19
- Healthcare Decision-Making and Restraints
- Health Systems, Economic Evaluations, Quality of Life
- Neuroscience of respiration and sleep
- Protein Kinase Regulation and GTPase Signaling
University Hospital of Basel
2017-2025
University of Basel
2018-2025
Deutsche Gesellschaft für Urologie
2011-2025
Marie Curie
2025
University College London
2025
Hospital Base
2022-2023
Faculty (United Kingdom)
2023
Kantonsspital Aarau
2022
Kantonsspital Baselland
2022
University of Göttingen
2020
The existence of an intracellular pool fatty acid translocase (FAT/CD36), 88-kDa membrane transporter for long-chain acids (FAs), and the ability insulin to induce translocation events prompted us investigate direct effects on cellular uptake FA by heart. Insulin (0.1 nmol/l higher) increased isolated rat cardiac myocytes 1.5-fold. This insulin-induced increase in was completely blocked phloretin, sulfo-N-succinimidylpalmitate (SSP), wortmannin, indicating involvement FAT/CD36 dependence...
Sleepiness whilst driving constitutes a road safety risk. Sleep-related breathing disorders are the most frequent medical cause of daytime sleepiness, and untreated patients with this condition have been shown to be at higher risk having accidents while driving. This study addressed question extent which treatment sleep-disordered by nasal continuous positive airway pressure (nCPAP) is related changes in patient's accident Seventy eight male requiring sleep-related nCPAP were enrolled study....
Using isolated rat cardiomyocytes we have examined: 1) the effect of insulin on cellular distribution glucose transporter 4 (GLUT4) and GLUT1, 2) total amount these transporters, 3) co-localization GLUT4, secretory carrier membrane proteins (SCAMPs) in intracellular membranes. Insulin induced 5.7- 2.7-fold increases GLUT4 GLUT1 at cell surface, respectively, as determined by nonpermeant photoaffinity label...
Background Due to the dramatic measures accompanying isolation and general uncertainty fear associated with COVID-19, patients relatives may be at high risk for adverse psychological outcomes. Until now there has been limited research focusing on prevalence of distress factors in COVID-19 their relatives. The objective our study was assess 30 days after hospital discharge. Methods In this prospective observational cohort two Swiss tertiary-care hospitals we included consecutive adult...
Abstract Patients discharged from intensive care are at risk for post-intensive syndrome (PICS), which consists of physical, psychological, and/or neurological impairments. This study aimed to analyze PICS 24 months follow-up, identify potential factors PICS, and assess health-related quality life in a long-term cohort adult cardiac arrest survivors. prospective included survivors admitted the unit Swiss tertiary academic medical center. The primary endpoint was prevalence defined as...
COVID-19 causes psychological distress for patients and their relatives at short term. However, little research addressed the longer-term outcomes in this population. Therefore, we aimed to prospectively assess clinically relevant hospitalized with 90 days after hospital discharge.This exploratory, prospective, observational cohort study included consecutive adult two Swiss tertiary-care hospitals between March June 2020 confirmed relatives. The primary outcome was defined as symptoms of...
Abstract Background The PROLOGUE score (PROgnostication using LOGistic regression model for Unselected adult cardiac arrest patients in the Early stages) is a novel prognostic prediction of neurological outcome after arrest, which showed exceptional performance internal validation. aim this study to validate an independent cohort unselected and compare it thoroughly validated Out-of-Hospital Cardiac Arrest (OHCA) Hospital Prognosis (CAHP) scores. Methods This included consecutive admitted...
AIMS OF THE STUDY: Interprofessional ward rounds are a cornerstone of patient-centred care for medical inpatients and offer opportunities to discuss coordinate patient treatment further management. We aimed identify factors associated with lower satisfaction efficiency interprofessional rounds, as reported by physicians nurses. METHODS: An anonymous Swiss nationwide online survey nurses was conducted in 28 internal medicine inpatient departments between 9 August 19 October 2023. Analyses...
Abstract Background Time to treatment is a significant predictor of mortality in emergency department (ED) patients with bacterial sepsis. Strategies for the early detection infection and sepsis are lacking. Clinical gestalt tool assessing synthesizing entire clinical picture, focusing on first impression at presentation. Objective This study aimed assess ED physicians’ prediction presenting signs symptoms infection. Design Prospective, observational 30-day follow-up. Participants Patients...
Abstract Background This study aimed to evaluate whether a blended learning course improves medical students’ communication skills compared face-to-face only lecture. Methods After completing lecture on skills, 2nd year students were gender-matched and randomized either an intervention receiving interactive video-based online module covering the content of previous including knowledge assessment or control group assessment. The primary endpoint was about techniques assessed by predefined...
Introduction Intensive care unit patients are at risk for post-intensive syndrome (PICS), which includes psychological, physical and/or cognitive sequelae after their hospital stay. Our aim was to investigate PICS in adult with out-of-hospital cardiac arrest (OHCA). Methods In this prospective observational cohort study, we assessed risks 3 and 12-month follow-up within the following domains: a) impairment (EuroQol [EQ-5D-3L]), b) functioning (Cerebral Performance Category [CPC] score >1,...