Michael Peirone

ORCID: 0000-0001-6058-0447
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Pancreatic function and diabetes
  • Prosthetics and Rehabilitation Robotics
  • Pluripotent Stem Cells Research
  • Muscle activation and electromyography studies
  • Stroke Rehabilitation and Recovery
  • Neuroscience and Neural Engineering
  • Tissue Engineering and Regenerative Medicine
  • Xenotransplantation and immune response

University of Victoria
2024

McMaster University
1998

Microencapsulation of recombinant “universal” cells with immunoprotective membranes is an alternate approach to somatic gene therapy. Therapeutic products secreted by these can be delivered different patients without immunosuppression or genetic modification the host's cells. The encapsulation mammalian cell types (epithelial cells, fibroblasts, and myoblasts) compared among three alginate-based microcapsules: (1) calcium-linked alginate microcapsules a solubilized core...

10.1002/(sici)1097-4636(19981215)42:4<587::aid-jbm15>3.0.co;2-x article EN Journal of Biomedical Materials Research 1998-12-15

An alternative and potentially cost-effective approach to somatic gene therapy is engineer a universal cell line secreting the desired product suitable for implantation into different patients without immune rejection. Encapsulating these cells in immunoprotective alginate microcapsules showed that this was effective treating murine models of human diseases. We now report also delivering recombinant products large animals. Canine MDCK encapsulated were able deliver growth hormone...

10.1089/hum.1998.9.2-195 article EN Human Gene Therapy 1998-01-20

Victoria Hand Project (VHP) is a Canadian charity with mission to provide 3D printed prosthetic arms people in-need across the world, by partnering care providers. This article explores journey of VHP, sharing insights, lessons learned, ongoing directions, and impact printing on for upper-limb amputation. Benefits such as affordability customization are explored, well challenges encountered, including quality control steep learning curve associated working in digital space. Through this...

10.33137/cpoj.v6i2.42142 article EN cc-by Canadian Prosthetics & Orthotics Journal 2024-01-12

Microencapsulation of recombinant "universal" cells with immunoprotective membranes is an alternate approach to somatic gene therapy. Therapeutic products secreted by these can be delivered different patients without immunosuppression or genetic modification the host's cells. The encapsulation mammalian cell types (epithelial cells, fibroblasts, and myoblasts) compared among three alginate-based microcapsules: (1) calcium-linked alginate microcapsules a solubilized core...

10.1002/(sici)1097-4636(19981215)42:4<587::aid-jbm15>3.3.co;2-o article EN Journal of Biomedical Materials Research 1998-12-15

We welcome the global community of professionals involved in care persons need prosthetic, orthotic, mobility and assistive devices to ISPO 18th World Congress! [View Programme Overview Oxford Abstracts](https://virtual.oxfordabstracts.com/#/e/ispo2021/program) I Abstract Book](https://journals.lww.com/poijournal/toc/2021/12001) | [HowToTreat Edition](https://360-ot.de/howtotreat/)

10.26226/morressier.614ca2d887a68d83cb5d5d0f preprint EN 2021-10-22
Coming Soon ...