A5000171148- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Sulfur Compounds in Biology
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Synthesis and Characterization of Heterocyclic Compounds
- Analytical Chemistry and Sensors
- Analytical Chemistry and Chromatography
- Metal complexes synthesis and properties
- Electrochemical Analysis and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Covalent Organic Framework Applications
- Mesoporous Materials and Catalysis
- Synthesis and properties of polymers
- Chemical and Physical Studies
- Free Radicals and Antioxidants
- Synthesis and biological activity
- Pharmacy and Medical Practices
- Multicomponent Synthesis of Heterocycles
- Conducting polymers and applications
- Microfluidic and Capillary Electrophoresis Applications
- Photochromic and Fluorescence Chemistry
- Organic Light-Emitting Diodes Research
- Nanocluster Synthesis and Applications
Hunan City University
2009-2024
University of South China
2015
Hunan University
2011-2015
University of Jinan
2015
Jinan University
2015
State Key Laboratory of Chemobiosensing and Chemometrics
2015
Cicatelli Associates
2012
Shaanxi Research Association for Women and Family
2005
Hunan Normal University
2005
Based on a new coumarin-BODIPY platform, compound 4 was rationally designed and synthesized as novel ratiometric fluorescent sensor for fluoride anions. The exhibited large red shift (88 nm) in absorption drastic response (I(472)/I(606) = 17.4) to Density function theory time-dependent density calculations were conducted rationalize the optical of sensor.
A novel highly reactive ratiometric fluorescent cyanide probe was judiciously designed based on 2-formylacrylonitrile moiety as a new reaction site. DFT study conducted to rationalize the extremely high reactivity nature of probe.
A new family of boron difluoride-rigidified dyes, phenanthro[9,10-d]imidazole-quinoline difluoride (PQBD), with solid-state fluorescence has been designed and synthesized. The novel series PQBD are advantageous over the typical dyes such as BODIPYs in terms large Stokes shift red solid state.
Single probe, multiple targets: The design and synthesis of a new probe is described that can readily discriminate Zn2+ Cd2+ with different fluorescence signals (see figure). studies Job's plot, mass spectroscopy, DFT calculations, 1H NMR spectroscopy reveal the has possible distinct binding modes to Cd2+. This work may open up opportunities for development single fluorescent probes sense targets interest. Detailed facts importance specialist readers are published as "Supporting...
Abstract Dual‐excitation ratiometric fluorescent probes allow the measurement of fluorescence intensities at two excitation wavelengths, which should provide a built‐in correction for environmental effects. However, most small‐molecule dual‐excitation that have been reported thus far shown rather limited separation between wavelengths (20–70 nm) and/or very small molar absorption coefficient one wavelengths. These shortcomings can lead to cross‐excitation and errors in ratios. Herein, we...
We have designed and synthesized the highly selective reversible fluorescent chemosensor 1 for Au(3+) by modifications on copper chemodosimeter 2, we further demonstrated that could be employed to image in living cells.
Abstract Hemicyanine dyes, with a tunable optical site and high wavelength tailorability, are of significant importance in the fields sensing diagnosis. Following discovery near-infrared (NIR) (650–900 nm) fluorescent dyes Changsha (CS) Huda (HD) by our group, remarkable progress has been made development hemicyanine-based probes for vivo imaging detecting. In this review, we summarize key contributions group developing long-wavelength (650–1700 hemicyanines utilizing them to construct...
Abstract A rhodamine/coumarin‐based ratiometric fluorescent Fe 3+ sensor has been designed and synthesized. The exhibits a good response to ions with high sensitivity, selectivity large shift in the emission spectra (>100 nm), which shows ‐induced FRET OFF–ON PET ON–OFF behavior. Copyright © 2015 John Wiley & Sons, Ltd.
A turn-on fluorescent probe Coumarin-SO2 based on a nucleophilic addition reaction was developed for the rapid detection of SO3(2-) in aqueous media. The displays excellent water solubility, fast response, highly sensitivity and selectivity over other biological related species. More importantly, living cell imaging experiments indicate feasibility using systems.
We propose a practical strategy to design series of NIR wavelength xanthene-quinoline salt-based heavy-atom-free synergistic photosensitizers by simply replacing the indole salt xanthene Changsha with quinoline salt.
A near-infrared fluorescent probe NIR-Hg, for the detection of Hg2+ ion, has been synthesized directly by condensing Changsha dye with 4-Phenyl-3-thiosemicarbazide and structure fully characterized 1HNMR, 13CNMR, ESI-MS. The designed on basis reaction that ion promotes thiosemicarbazide to oxazole in aqueous media had induced produce turn-on fluorescence via an irreversible spirolactam ring-opening process. NIR-Hg exhibited fast response (1 min), high sensitivity 44-fold intensity...
Abstract Compounds Rh6G-1 and RhB-2 with a novel receptor composed of tri-oxygen atoms amide groups were designed synthesized as new reversible fluorescent sensors for Fe 3+ . The prominent features the sensor include large fluorescence turn-on response in essentially pure water at room temperature, high sensitivity, selectivity, limit detection, cell membrane permeability, low cytotoxicity. These desirable attributes enable us to successfully employ bioimaging living cells.
Abstract Review: 50 refs.