A5024069939- Schizophrenia research and treatment
- COVID-19 and Mental Health
- Suicide and Self-Harm Studies
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Mental Health Treatment and Access
- Psychological Well-being and Life Satisfaction
- Genetic Associations and Epidemiology
- Eating Disorders and Behaviors
- Bipolar Disorder and Treatment
- Sleep and related disorders
- Digital Mental Health Interventions
- Health and Wellbeing Research
- Tryptophan and brain disorders
- Diverse Approaches in Healthcare and Education Studies
- Diet and metabolism studies
- Child Nutrition and Feeding Issues
- Obsessive-Compulsive Spectrum Disorders
- Health disparities and outcomes
- Advanced Neuroimaging Techniques and Applications
- Neurotransmitter Receptor Influence on Behavior
- COVID-19 Pandemic Impacts
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Treatment of Major Depression
Chonnam National University
2013-2025
Gwangmyeong Mental Health Welfare Center
2019-2025
Chonnam National University Hospital
2010-2022
Samsung Medical Center
2007-2017
Sungkyunkwan University
2006-2017
Ministry of Food and Drug Safety
2017
Catholic Kwandong University
2014
Chungnam National University
2013
National University College
2013
Wonkwang University
2013
We investigated the effect of coronavirus disease-2019 (COVID-19) pandemic on suicide trends in Korea via a time-series analysis. used Facebook Prophet to generate forecasting models based monthly numbers deaths between 1997 and 2018, validated by comparison with 2019 numbers, predicted suicides 2020. compared expected observed during COVID-19 pandemic. The total did not deviate from projections pre-pandemic period. However, number among women those under age 34 years significantly exceeded...
Abstract Background The aim of this study was to compare the results laparoscopy-assisted total gastrectomy with those open for early gastric cancer. Methods Patients cancer who underwent curative intent in three Korean tertiary hospitals between January 2003 and December 2010 were included multicentre, retrospective, propensity score-matched cohort study. Cox proportional hazards regression models used evaluate association operation method survival. Results A 753 patients There no...
These two cohorts were designed to examine the increasing burden of chronic diseases among Korean populations. The studies investigated determinants for stroke, osteoporosis, dementia and cancer middle-aged elderly Namwon Study baseline survey was performed between 2004 2007 (n = 10 667), followed up 4 years later 8157, follow-up rate 76.5%). Dong-gu administered over 2007–2010 9260), will be 2014 2015. Questionnaires included assessment cognitive function, psychiatric health lifestyle...
In this study, we aimed to develop a model predicting individuals with suicide ideation within general population using machine learning algorithm.Among 35,116 aged over 19 years from the Korea National Health & Nutrition Examination Survey, selected 11,628 via random down-sampling. This included 5,814 ideators and same number of non-suicide ideators. We randomly assigned subjects training set (n=10,466) test (n=1,162). set, forest was trained 15 features recursive feature elimination...
Pharmacogenetic studies on clozapine (CLZ) have provided meaningful insights but shown redundancies owing to wide interindividual variability and insufficient replication. The present study was designed validate hitherto suggested candidate genes CLZ pharmacokinetics pharmacodynamics explore new markers through an integrative study.Based a literature review, total of 127 variations in 27 were selected analyzed. Ninety-six schizophrenic patients Korean ethnicity with constant dosing...
This study aimed to investigate abnormalities in the gray matter and white (GM WM, respectively) that are shared between schizophrenia (SZ) bipolar disorder (BD). We used 3T-magnetic resonance imaging examine patients with SZ, BD, or healthy control (HC) subjects (aged 20–50 years, N = 65 each group). generated modulated GM maps through voxel-based morphometry (VBM) for T1-weighted images skeletonized fractional anisotropy, mean diffusion, radial diffusivity tract-based special statistics...
Abstract Background The risk of depression has risen in the general population during COVID-19 epidemic. This study was conducted to explore and protective factors associated with among uninfected by COVID-19. Methods A cross-sectional 1,500 representative South Korean citizens aged 19–65 years through an anonymous online survey. Depression defined as a Patient Health Questionnaire-9 score 10 or higher. Other questionnaires included one measuring psycho-behavioural social changes, stress,...
In this study, we investigated the impact of inflammatory cytokines on cognitive performance patients with schizophrenia. The included met criteria for schizophrenia spectrum disorder and were aged between 15 40 years, a duration illness ≤1 year. Plasma tumor necrosis factor (TNF)-α; interferon-γ; interleukin (IL)-1β, IL-6, IL-8, IL-10, IL-12 levels measured. A computerized neurocognitive battery, measures social function, clinical administered. total 174 first-episode psychosis enrolled....
This study investigated trends in hospital utilization by patients with schizophrenia during the first wave of COVID-19 outbreak Korea.The Prophet algorithm was used to predict monthly number 2020 based on medical insurance data between 2010 and 2019. The projected expectations were compared actual receiving outpatient inpatient treatment each month half 2020. We conduct interrupted time series analyses short-term determine significance recent changes trend visits schizophrenia.The...
Abstract Adverse effects of atypical antipsychotics (AAP) can include obsessive–compulsive (OC) symptoms. Based on biological evidence the relationship between glutamatergic system and both OC disorder AAP, this study aimed to determine whether DLGAP3 , coding a post‐synaptic scaffolding protein synapses, is associated with AAP‐induced Furthermore, we explored interactions previously reported susceptibility gene, glutamate transporter gene SLC1A1 regarding phenotype. Subjects were clinically...
This study investigates the clinical nature, prevalence rates, and associated factors of second-generation antipsychotic (SGA)–related tardive dyskinesia dystonia. To date, these subjects have not been thoroughly investigated. The were 80 non-elderly schizophrenic patients who received SGAs for more than 1 year without any previous exposure to first-generation antipsychotics. Multiple (≥2) direct assessments movement symptoms performed. Hospital records longer recent describing observed...
This study investigated whether resting-state functional connectivity is associated with long-term clinical outcomes of patients schizophrenia. Resting-state brain images were obtained from 79 outpatients schizophrenia and 30 healthy controls (HC), using a 3 T-MRI scanner. All 20–50 years old >3 years' duration illness appeared clinically stable. We assessed their psychopathology the 18-item Brief Psychiatric Rating Scale (BPRS-18) divided them into "good," "moderate," "poor" outcome (SZ-GO,...
Neuroinflammation contributes to the pathophysiology of various mental illnesses including schizophrenia. We investigated peripheral inflammatory cytokines as a biomarker for predicting symptomatic remission in patients with first-episode The study included 224 aged 15-60 years who fulfilled criteria schizophrenia spectrum disorder treatment duration ≤6 months. Serum levels tumor necrosis factor (TNF) -α, interferon-γ, interleukin (IL)-1α, IL-1β, IL-6, IL-8, IL-10, and IL-12 were measured....
Stigma influences perceptions of mental illness and novel diseases like coronavirus disease-2019 (COVID-19), often impeding healthcare access despite advancements in medical treatment. This study compares the stigma associated with COVID-19 to identify factors that could help reduce stigma. An online survey was conducted May 2023 among 1,500 participants aged 19 65 South Korea, using a panel from Embrain, an service. The assessed distress related validated questionnaire. It collected...
Objective Despite increasing research on digital technologies for psychiatric disorders, studies specifically examining self-monitoring of symptoms with smartphone applications by patients schizophrenia remain limited. This study aims to evaluate the validity and reliability using a application among at Mindlink, community-based early intervention center. Methods Fifty-three young spectrum disorders participated. They rated their across five domains—delusions, hallucinations, anxiety,...
Objective We designed a nationwide study with limited exclusion criteria to investigate the prevalence of metabolic syndrome (MetS) in Korea and its relationship antipsychotic medications. Methods This multicenter, cross-sectional, observational included patients diagnosed schizophrenia or schizoaffective disorder. Sixteen hospitals enrolled 845 aged 18 65 years prescribed any medication between August 2011 2013. MetS was using modified Adult Treatment Panel III National Cholesterol...
This study aimed to investigate cognitive impairment and psychological distress of critically ill patients at discharge from intensive care unit (ICU). included 30 who had neither pre-existing dementia nor ongoing delirium. At ICU discharge, they performed a screening test for (Mini-Cog test) completed questionnaires depression (Patient Health Questionnaire-2, PHQ-2) 4 stressful experiences during stay including nightmares, severe anxiety or panic, pain, trouble breathe feeling suffocation...
Background Findings from family studies and recent genome-wide association have indicated overlap in the risk genes between schizophrenia bipolar disorder (BD). After finding a linkage ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sicalyltransferase 2 gene) locus (15q26) mixed families with BD, several reported significant this gene or BD. We investigated genetic both BD Korean population. Methods A total of 582 patients schizophrenia, 339 502 healthy controls were included. Thirty-one...
Objectives: This study aimed to compare psychosocial distress in areas Korea with different prevalence of coronavirus disease 2019 (COVID-19) after validating a questionnaire on psychological experiences and stress associated the outbreak. Methods: Using an online-based survey, COVID-19 was investigated three regions, which were selected according their COVID-19. A total 1,500 people from online public panel regions participated study. The included sociodemographic information, experience...
We examined the effects of mass media usage on people's level knowledge about coronavirus disease 2019 (COVID-19), fear infection, prejudice towards infected people, and anxiety level. In addition, we investigated whether COVID-19 can reduce fear, prejudice, anxiety.
Korea has witnessed significant fluctuations in its suicide rates recent decades, which may be related to modifications death registration system. This study aimed explore the structural shifts trends, as well accidental and ill-defined deaths Korea, analyze patterns of these changes.