- Dementia and Cognitive Impairment Research
- Parkinson's Disease Mechanisms and Treatments
- Technology Use by Older Adults
- Frailty in Older Adults
- Cognitive Functions and Memory
- Alzheimer's disease research and treatments
- Traumatic Brain Injury Research
- Autism Spectrum Disorder Research
- Health, Environment, Cognitive Aging
- Traumatic Brain Injury and Neurovascular Disturbances
- Health Systems, Economic Evaluations, Quality of Life
- Neurological disorders and treatments
- Stroke Rehabilitation and Recovery
- Neurobiology of Language and Bilingualism
- Health disparities and outcomes
- Assistive Technology in Communication and Mobility
- Geriatric Care and Nursing Homes
- Pain Management and Placebo Effect
- Impact of Technology on Adolescents
- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Older Adults Driving Studies
- Aging and Gerontology Research
- Psychosomatic Disorders and Their Treatments
- Mental Health Treatment and Access
Baylor Scott & White Health
2013-2025
Bryan College
2019-2025
The University of Texas at Austin
2021-2024
The University of Texas Health Science Center at Houston
2023-2024
University of Florida Health
2022
University of Florida
2022
Baylor Scott & White Medical Center - Temple
2014-2021
University of Pennsylvania
2021
Neurosciences Institute
2014-2021
Baylor Medical Center at Garland
2015-2021
Clinicians and researchers who measure cognitive dysfunction often use the Alzheimer's Disease Assessment Scale--Cognitive Subscale (ADAS-Cog), Mini-Mental State Examination (MMSE), or Clinical Dementia Rating scale (CDR-SOB). But, of different measures can make it difficult to compare data across patients studies. What is needed a simple chart that shows how scores on these three important correspond each other.Using from 1709 participants Neuroimaging Initiative item response theory-based...
Abstract Blast injury is common in current warfare, but little known about the effects of blast-related mild traumatic brain (mTBI). Profile analyses were conducted investigating differences self-reported postconcussive (PC) symptoms 339 veteran outpatients with mTBI histories reporting based on mechanism (blast only, nonblast or both blast and nonblast), number injuries, distance from blast. Veterans any history younger reported higher posttraumatic stress than veterans nonblast-related...
A decline in the ability to perform daily intentions-known as prospective memory-is a key driver of everyday functional impairment dementia. In absence effective pharmacological treatments, there is need for developing, testing, and optimizing behavioral interventions that can bolster memory functioning. We investigated feasibility efficacy smartphone-based strategies persons with cognitive impairment.Fifty-two older adults (74.79 ± 7.20 years) meeting diagnostic criteria mild or dementia...
Veterans with a history of mild traumatic brain injury (mTBI) are reporting postconcussive symptoms (PCSx) in addition to experiencing postdeployment physical and emotional comorbidities. The Health Administration has mandated specialized evaluation treatment for veterans mTBI suggested widespread use the Neurobehavioral Symptom Inventory (NSI) as measure PCSx. This study evaluated NSI's factor structure assessed impact posttraumatic stress (PTS) on scale at item levels.Five hundred...
Abstract Objective An increasing focus in Alzheimer’s disease and aging research is to identify transitional cognitive decline. One means of indexing change over time serial evaluations calculate standardized regression-based (SRB) indices. This paper includes development preliminary validation SRB indices for the Uniform Data Set 3.0 Neuropsychological Battery, as well base rate data aid their interpretation. Method The sample included 1341 cognitively intact older adults with assessments...
<i>Background/Aims:</i> The Alzheimer’s Disease Assessment Scale-cognitive (ADAS-cog) is regularly used to assess cognitive dysfunction in disease (AD) clinical trials. Yet, little known about how the instrument and its subscales measure cognition across spectrum of AD. current investigation item response theory (IRT) analyses measurement properties ADAS-cog range <i>Methods:</i> We IRT-based establish relationship between probability obtaining observed scores on each...
The Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog) is a commonly used measure for assessing cognitive dysfunction in patients with disease (AD). has 11 subscales, each of which captures an important aspect AD. Traditional scoring the ADAS-cog involves adding up scores from subscales without regarding their varying difficulty or strength relationship to AD-associated dysfunction. present article analyzes problems associated this approach and offers solutions gaining measurement...
Abstract Objective: The goals of this study were to (1) specify the factor structure Uniform Dataset 3.0 neuropsychological battery (UDS3NB) in cognitively unimpaired older adults, (2) establish measurement invariance for model, and (3) create a normative calculator scores. Methods: Data from 2520 intact adults submitted confirmatory analyses testing across sex, age, education. Additionally, subsample dataset was used examine over time using 1-year follow-up data ( n = 1061). With...
Digital technologies permit new ways of performing instrumental activities daily living (iADLs) for older adults, but these approaches are not usually considered in existing iADL measures. The current study investigated how a sample adults report using digital versus analog iADLs.
Objective: We developed the Technology in Caring Questionnaire (TCQ) to assess use of technology-based strategies by dementia caregivers. Methods: One hundred caregivers completed a survey that included TCQ items along with measures technology proficiency and patient caregiver-centered outcomes. Results: The final 34-item scale had adequate excellent internal consistency (raw Cronbach alpha = 0.75; standardized 0.95; Guttman lambda-6 0.97). scores demonstrated modest convergent associations...
Abstract Cognitive and affective complaints are common in patients with primary hyperparathyroidism (PHPT), but few studies have used psychometric testing to document these symptoms their response parathyroidectomy. The current study sought clarify the nature of cognitive impairments PHPT changes postparathyroidectomy. One hundred eleven underwent neuropsychological evaluation prior parathyroidectomy 68 returning for an early postsurgical evaluation. Changes cognition were assessed using...
Low neuropsychological test scores are commonly observed even in cognitively healthy older adults. For batteries designed to assess for and track cognitive decline adults, documenting the multivariate base rates (MBRs) of low is important differentiate expected from abnormal score patterns. Additionally, it our understanding mild impairment preclinical declines determine how such patterns predict future clinical states.
Objective: In the current pandemic, tele-screening of neuropsychological status has become a necessity. Instruments developed for telephone screening are not as well validated traditional measures. Therefore, study presents preliminary validation version Montreal Cognitive Assessment (T-MoCA) in individuals with Parkinson's disease (PD).Method: Twenty-one persons PD completed T-MoCA along battery. Diagnostic accuracy presence PD-related mild cognitive impairment (MCI) and correlations...
Delays in seeking care compromise diagnosis, treatment options, and outcomes ischemic strokes. This study identified factors associated with time between stroke symptom onset emergency department (ED) arrival at a private nonprofit medical center serving large rural catchment area central Texas, the goal of identifying symptomatic, demographic, historical that might influence care.Demographic clinical data from tertiary center's Get With The Guidelines (GWTG) database were evaluated 1874...
Objective Compare the construct validity and predictive utility of cognitive intraindividual variability (IIV) in a sample community-dwelling Hispanic non-Hispanic white (NHW) older adults.
Smartphones have potential as cognitive aids for adults with impairments. However, little is known about how patients and their care partners utilise smartphones in day-to-day lives. We collected self-reported smartphone utilisation data from referred neuropsychological evaluations (N = 53), 44), an Amazon Mechanical Turk control sample 204). Patient participants were less likely to own a than controls, increasing age associated of features all groups. Of the who owned smartphones,...
Abstract Objective An increasing focus in Alzheimer’s disease and aging research is to identify transitional cognitive decline. One means of indexing change over time serial evaluations calculate standardized regression-based (SRB) indices. This paper includes the development preliminary validation SRB indices for Uniform Data Set 3.0 Neuropsychological Battery, as well base rate data aid their interpretation. Method The sample included 1,341 cognitively intact older adults with assessments...
Purpose: To evaluate whether certain preinduction clinical characteristics may influence the success rate of induction. Methods: We prospectively enrolled and attempted inductions on 51 patients who were suspected to have psychogenic nonepileptic events based grounds. In addition careful examination reported ictal semiology, we administered a battery four psychological instruments our patients. Key Findings: found that among 42 cases successful induction, 92.9% (n = 39) these successfully...
To meet a diagnosis for particular personality disorder (PD), among other requirements, person must exhibit specified minimum number of the features outlined that PD, otherwise referred to as diagnostic threshold. Despite many years research on DSM PDs, there is little empirical basis chosen thresholds. The present study used mechanisms item response theory (IRT) link thresholds six PDs their corresponding level latent PD pathology. Consistent with our hypothesis, analyses data from 41,227...